A Novel Risk Factor for Cardiovascular Disease: The Insomnia-Short Sleep Phenotyp
A Novel Risk Factor for Cardiovascular Disease: The Insomnia-Short Sleep Phenotyp
批准号:
8987442
负责人:
Christopher Edward Kline
金额:
$16.66万
依托单位国家:
美国
项目类别:
财政年份:
2014
资助国家:
美国
项目状态:
已结题
起止时间:
2014-01-01 至 2018-12-31
关键词:
AccountingAddressAdultAffectAreaArousalAttenuatedBedsBehavior TherapyBehavioralCardiovascular DiseasesCardiovascular systemClinicalCognitive TherapyCombined Modality TherapyDataDevelopmentDiagnosisDiagnostic and Statistical Manual of Mental DisordersDietDisease MarkerElectroencephalographyEpidemiologic StudiesEpidemiologyExerciseExhibitsFoundationsFrequenciesGoalsHigh PrevalenceHydrocortisoneHypertensionInsulin ResistanceK-Series Research Career ProgramsLinkMeasurementMeasuresMediatingMental DepressionMetabolicMorbidity - disease rateMyocardial InfarctionNeurosecretory SystemsObstructive Sleep ApneaParticipantPhenotypePhysiologicalPopulationPrognostic MarkerRandomized Controlled TrialsResearchResearch PersonnelRiskRisk FactorsRoleSafetySamplingSeveritiesSleepSleep Apnea SyndromesSleep DisordersSleep disturbancesSleeplessnessTestingTimeTrainingTreatment EfficacyWorkbrachial arterycardiovascular disorder riskcareerclinically relevantdesignexercise trainingexperienceheart rate variabilityimprovedindexinginsulin sensitivitymeetingsmortalitynovelphysical inactivitypopulation basedprimary outcomepublic health relevancesecondary outcomeurinary
中文摘要
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英文摘要
DESCRIPTION (provided by applicant): Cardiovascular disease (CVD) is the world's leading cause of morbidity and mortality, and evidence is mounting that sleep disturbance-which is chronically experienced by approximately one-third of the adult population-may be a prominent risk factor. The majority of research thus far has focused on the cardiovascular consequences of sleep disordered breathing, though there is compelling epidemiologic evidence that insomnia, particularly insomnia with short sleep duration, may be associated with increased CVD risk. Identification of increased CVD risk for this sleep phenotype would have significant
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