Disentangling subclinical cardiovascular risk associated with insomnia, short sleep duration, and their combination

解开与失眠、睡眠时间短及其组合相关的亚临床心血管风险

• 批准号: 9808185
• 负责人: Christopher Edward Kline
• 金额: $ 7.78万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-10 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9808185
• 关键词: Address; Adult; Anxiety; Attention; Behavior Therapy; Behavioral; Cardiovascular Diseases; Clinical; Comorbidity; Data; Diagnosis; Diet; Exhibits; Goals; Grant; Health; High Prevalence; Hour; Individual; Knowledge; Link; Measures; Mediating; Mental Depression; Morbidity - disease rate; Patients; Physiologic pulse; Prognostic Marker; Psychiatric Diagnosis; Public Health; Reporting; Research; Research Project Grants; Risk Factors; Sampling; Sampling Studies; Sleep; Sleep Apnea Syndromes; Sleep Deprivation; Sleep disturbances; Sleeplessness; Smoking; Subgroup; Uncertainty; Work; base; brachial artery; cardiovascular disorder risk; cardiovascular risk factor; clinical Diagnosis; design; epidemiology study; indexing; insulin sensitivity; mortality; physical inactivity; population based; primary outcome; public health relevance; targeted treatment

PROJECT SUMMARY/ABSTRACT Cardiovascular disease (CVD) is the world’s leading cause of morbidity and mortality, and evidence is mounting that poor sleep may be a significant behavioral risk factor for CVD. Although the majority of current research has focused on the CVD risk associated with sleep disordered breathing (SDB), an emerging body of evidence suggests that insomnia, short sleep duration, and, most prominently, the combination of insomnia and short sleep, may also confer significant CVD risk. Identification of insomnia, short sleep duration, and/or their combination as a behavioral risk factor for CVD would have significant

项目总结/摘要 心血管疾病（CVD）是世界上发病率和死亡率的主要原因，证据越来越多 睡眠不足可能是心血管疾病的一个重要行为风险因素。尽管目前的大多数研究都 关注与睡眠呼吸障碍（SDB）相关的心血管疾病风险， 提示失眠，睡眠时间短，最突出的是，失眠和睡眠时间短的组合， 睡眠，也可能带来显著的CVD风险。失眠、睡眠时间短和/或其 作为CVD的行为风险因素，