Clinical Research Design, Epidemiology, and Biostatistics Core

临床研究设计、流行病学和生物统计学（CRDEB） KCA将通过创建一个鼓励创新临床和转化研究的协调基础设施以及加强对新老研究人员的培训，在实现加速将科学发现转化为改善健康的ctrl - in目标方面发挥关键作用。大多数MWRC合作机构认识到，从最初的研究设计到数据分析和结果的有效沟通，临床研究设计、流行病学和生物统计学对调查至关重要。因此，在整个MWRC中，这些领域存在许多独立的努力，并且在某种程度上是自主运作的。然而，对一些研究人员来说，获取信息存在多重障碍。虽然许多成功和有名望的研究人员可以进入这些小组，但其他研究人员的访问可能是有限和偶然的，特别是对更初级的研究人员。此外，没有向调查人员提供这种支持的协调系统。此外，西部山区的断裂性质和地理障碍也削弱了临床研究设计、流行病学和生物统计学支持、合作和培训的有效整合和传播。为了克服这些障碍，ctrl - In将为临床和转化研究人员提供当地和中央联络点，这些研究人员在制定研究设计、生物统计方法和流行病学设计方面需要帮助。这将为临床和转化研究营造一个充满活力和富有成效的氛围，并促进所有研究者，包括新研究者和初级研究者的研究。

The Clinical Research Design, Epidemiology, and Biostatistics (CRDEB) KCA will play a crucial role in achieving the CTR-IN goal of accelerating the translation of scientific discovery into improved health by creating a coordinated infrastructure encouraging innovative clinical and translational research and enhancing our training of new and established researchers. The majority of MWRC partner institutions recognize that clinical research design, epidemiology, and biostatistics are critical to investigation, from initial study design through data analysis and the effective communication of results. As a result, a number of independent efforts in these areas exist throughout the MWRC and operate somewhat autonomously. However, multiple barriers to access exist for some researchers. While many successful and established researchers have access to these groups, other investigator's access may be limited and haphazard, particularly for more junior researchers. In addition, there is no coordinated system that provides such support to investigators. Also, the fractured nature and geographical barriers of the Mountain West have impaired the effective integration and dissemination of clinical research design, epidemiology, and biostatistics support, collaboration, and training. In order to overcome these barriers, the CTR-IN will provide local and central contact points for clinical and translational researchers who need assistance in developing study design, biostatistical methods, and epidemiological design. This will foster an energetic and productive climate for clinical and translational research and facilitate research for all investigators, including new and junior investigators.