Biostatistics & Biomedical Informatics Core

生物统计学

基本信息

批准号：
9271885
负责人：
Bryan Earl Shepherd
金额：
$ 30.18万
依托单位：
VANDERBILT UNIVERSITY MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9271885
关键词：
AIDS/HIV problem Acquired Immunodeficiency Syndrome Award Biometry Caring Clinic Clinical Clinical Research Clinical Sciences Collaborations Consultations Data Data Collection Data Linkages Data Science Data Set Databases Development Distributed Databases Doctor of Philosophy Epidemiologist Epidemiology Faculty Funding Goals Growth HIV Health Housing Informatics Institution Instruction International Journals Leadership Link Location Mentors Methods National Institute of Allergy and Infectious Disease Output Patients Primary Health Care Records Research Research Design Research Personnel Resource Informatics Resources Risk Factors Role Site Statistical Data Interpretation Statistical Methods Tennessee Time Training Training Support Translational Research Universities Walking biomedical informatics cohort experience improved informatics training innovation medical schools method development mid-career faculty novel population based professor programs research and development statistics synergism tool tool development

项目摘要

Biostatistics/Biomedical Informatics – PROJECT SUMMARY Thoughtful study design, data collection, statistical analysis, and tool development are essential to high quality HIV/AIDS research. The over-arching goal of the Tennessee Center for AIDS Research (TN-CFAR) Biostatistics and Biomedical Informatics Core (BBIC) is to elevate the quality of HIV/AIDS research. The BBIC will provide statistical and biomedical informatics support to HIV/AIDS investigators at Meharry Medical College (MMC), Vanderbilt University (VU), and the Tennessee Department of Health (TDH). Specific support includes a weekly biostatistics/biomedical informatics walk-in clinic rotating its location between the 3 institutions to maximize exposure and usage, consultation for all Development Core Award applicants prior to submission and guaranteed statistics/biomedical informatics coverage for award recipients, and active collaboration with TN-CFAR investigators. We also propose to develop novel resources, tools, and methods to enhance HIV/AIDS research at the participating institutions and beyond. As a major initiative, the BBIC will link databases at TDH, create a research-ready clinical database at MMC, and harmonize these databases with existing databases at Vanderbilt that will permit integrated HIV research across the TN-CFAR. The BBIC will also develop tools for data harmonization and record counting to allow efficient real-time queries across distributed databases, and develop statistical methods that incorporate subsets of validated data into estimation. Finally, the BBIC will support training by actively participating in seminars and journal clubs, sponsoring biostatistics/biomedical informatics seminars, and providing topic- specific instruction at walk-in clinics. The BBIC team has broad HIV research experience, including leadership roles in coordinating centers for large cohorts of HIV-infected patients, extensive collaborations with HIV investigators, and proven track records of developing novel methods and tools motivated by and beneficial to HIV research.

生物统计学/生物医学信息学 - 项目摘要周到的研究设计，数据收集，统计分析和工具开发是必不可少的高质量的艾滋病毒/艾滋病研究。田纳西州艾滋病中心的整理目标研究（TN-CFAR）生物统计学和生物医学信息学核心（BBIC）是提升艾滋病毒/艾滋病研究的质量。 BBIC将提供统计和生物医学信息范德比尔特大学Meharry医学院（MMC）的艾滋病毒/艾滋病调查员的支持（VU）和田纳西州卫生部（TDH）。具体支持包括每周一次生物统计学/生物医学信息信息诊所在这三个机构之间旋转其位置最大化暴露和使用，对所有开发核心奖励申请的咨询提交和保证的统计/生物医学信息信息覆盖颁奖者，以及与TN-CFAR研究人员的积极合作。我们还建议开发新的资源，工具和方法来增强参与机构及其他地区的艾滋病毒/艾滋病研究。作为一项重大计划，BBIC将在TDH上链接数据库，创建准备研究的临床 MMC的数据库，并将这些数据库与Vanderbilt的现有数据库协调将允许整个TN-CFAR的综合艾滋病毒研究。 BBIC还将为数据协调和记录计数以允许跨分布式的有效实时查询数据库，并开发统计方法，将经过验证的数据子集纳入估计。最后，BBIC将通过积极参与半货人来支持培训期刊俱乐部，赞助生物统计学/生物医学信息的半手，并提供主题 - 步入式诊所的具体指导。 BBIC团队拥有广泛的HIV研究经验，包括大量艾滋病毒感染患者的协调中心中的领导角色，与艾滋病毒调查人员的广泛合作，并经过验证的发展新颖的记录由艾滋病毒研究动机和有益的方法和工具。