Integrated Training in Quantitative and Experimental Cancer Systems Biology

项目概要 迫切需要一支由经过深度培训、数量丰富、经验丰富的肿瘤科医生组成的国家骨干队伍 在癌症的生物学方面和计算工具方面，以进一步了解和治疗。在 根据拟议的培训计划，OHSU 将利用其癌症计划的优势，从基本的 从科学到翻译，及其计算能力，从基因组学到机械建模。俄勒冈州立大学 最近在自然指数中被评为世界生命科学研究领域顶尖的年轻大学。一把钥匙 培训计划的强度需要定量和湿实验室基础或临床的共同指导 师资队伍。具有生物学或计算专业知识的博士后学员将获得广泛的 互补领域的培训，包括教学培训和研究培训。研究生学员将涉足这两个领域 从第一天起，就以现有课程和既定的教师专业知识为基础，专门设计课程， 以生物医学工程系和细胞、发育与癌症系为中心 生物学。培训教师在指导和研究生产力方面拥有出色的记录， 并辅之以一批健康的初级教师，以保持项目的长期生存能力。近40 最初将向受训人员提供教师，平均每年超过 80 万美元的研究经费。

Project Summary There is an outstanding need for a national cadre of quantitatively sophisticated oncologists, with deep training in both biological aspects of cancer and computational tools to further understanding and treatment. In the proposed training program, OHSU will leverage the strengths of both its cancer program, ranging from basic science to translation, and its computational capacity, spanning from genomics to mechanistic modeling. OHSU was recently ranked as the top young university in life sciences research in the world in the Nature Index. A key strength of the training program will be required co-mentorship by both quantitative and wet-lab basic or clinical faculty. Post-doctoral trainees arriving with expertise in either biology or computation will receive extensive training in the complementary field, both didactic and research-based. Graduate trainees will engage both fields from day one in a specially designed curriculum building on existing courses and established faculty expertise, centered in the Departments of Biomedical Engineering and the Department of Cell, Developmental & Cancer Biology. The training faculty have outstanding track records in mentorship and research productivity, complemented by a healthy cohort of junior faculty to maintain program viability over the long term. Nearly 40 faculty will initially be available to trainees, with an average of >$800,000/year in research funding.