Air Quality, Child, and Adult Health in Homes Where E-Cigarettes Are Smoked
Air Quality, Child, and Adult Health in Homes Where E-Cigarettes Are Smoked
批准号:
9412238
负责人:
Terry Gordon
金额:
$50.16万
依托单位国家:
美国
项目类别:
财政年份:
2017
资助国家:
美国
项目状态:
已结题
起止时间:
2017-09-15 至 2021-08-31
关键词:
AcuteAdolescentAdoptedAdoptionAdultAerosolsAirAir PollutantsAreaBiological MarkersBloodBlood PressureCD40 LigandCarbon MonoxideCardiopulmonaryCardiovascular DiseasesCardiovascular PhysiologyChemicalsChildChronicChronic DiseaseCigaretteClinicalCommunity HealthConsumptionDangerousnessElectronic cigaretteEnvironmental Tobacco SmokeEpithelial CellsExposure toFibrinogenFlavoringFrightFutureGlycerolHandHarm ReductionHealthHeatingHome environmentHouseholdIndividualLeadLung diseasesMainstreamingMorbidity - disease rateNasal cavityNicotineOral cavityP-SelectinParticulate MatterPhysiologicalPoisonPropylene GlycolsPublic HealthResearchResearch DesignRiskRisk FactorsSmokeSmokerSourceSpirometrySystemTestingTimeTobaccoTobacco smokingTobacco useTrace ElementsVascular Cell Adhesion Molecule-1cardiovascular disorder riskcigarette smokingcigarette smokingheart rate variabilityindexingintercellular cell adhesion moleculemortalitynon-smokingpolicy implicationpollutantpulmonary functionsmoking cessationtobacco exposuretranscriptomicsvaping
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Abstract
Electronic cigarettes (e-cigs), were introduced to the US market only 10 years ago, and are markedly different
from traditional cigarettes. Traditional cigarettes contain tobacco and are smoked through combustion, thereby
exposing the smoker and those nearby (secondhand smoke; SHS) to thousands of potentially dangerous
tobacco and combustion-related agents. In contrast, E-cigs are “vaped” rather than smoked, and the resultant
aerosols produced contain a far smaller number of potentially toxic chemicals, such as nicotine and flavorings,
as well as byproducts caused by the heating of propylene glycol, and glycerin. Thus, they are widely believed
and marketed as a safer alternative to cigarette smoking, yet the actual dangers posed by the use of these e-
cigarettes remains largely unexplored. Many see the widespread adoption of this alternative nicotine delivery
system as holding great promise in helping people quit or reduce cigarette use, and thus are seen as having
profoundly positive effects as harm reduction agents. Others fear that their use may lead adolescents (the
group most likely to begin using cigarettes) to transition from their use to the use of cigarettes. To date, missing
from this debate is the potential biologic harm of mainstream and secondhand e-cig aerosols in homes where
these agents are used, and how such exposure compares to mainstream and SHS from cigarettes. Our overall
hypothesis is that e-cig vaping in homes leads to exposure to aerosols containing a number of pollutants and
that this exposure is associated with decrements in cardiopulmonary function and increases in biomarkers for
risk of future pulmonary and cardiovascular disease both in the e-cig vaper and non-smoking/non-vaping
children and adults in such homes. Findings from this study will have very significant research and public
health implications by enhancing understanding of the potential dangers of e-cigs, which are rapidly increasing
in use and which many believe is a safe alternative to cigarette smoking and an aid to helping tobacco smoking
cessation.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
The adverse chronic effects of e-cigarettes: puff profiles, sex, genetics, and flavorings as modifying factors
-
批准号:9789228
-
项目类别:
-
资助金额:$36.57万
-
财政年份:2018
-
负责人:Terry Gordon
-
依托单位:
The adverse chronic effects of e-cigarettes: puff profiles, sex, genetics, and flavorings as modifying factors
-
批准号:9994260
-
项目类别:
-
资助金额:$37.71万
-
财政年份:2018
-
负责人:Terry Gordon
-
依托单位:
The adverse chronic effects of e-cigarettes: puff profiles, sex, genetics, and flavorings as modifying factors
-
批准号:10471771
-
项目类别:
-
资助金额:$36.95万
-
财政年份:2018
-
负责人:Terry Gordon
-
依托单位:
U.S.-Indo Air Quality and Health Workshop
-
批准号:9253924
-
项目类别:
-
资助金额:$1.5万
-
财政年份:2016
-
负责人:Terry Gordon
-
依托单位:
Strategies for Setting Occupational Exposure Limits for Engineered Nanomaterials
-
批准号:8396928
-
项目类别:
-
资助金额:$1.97万
-
财政年份:2012
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8282801
-
项目类别:
-
资助金额:$52.33万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8385075
-
项目类别:
-
资助金额:$5.56万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8397870
-
项目类别:
-
资助金额:$5.75万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8663595
-
项目类别:
-
资助金额:$51.8万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8147718
-
项目类别:
-
资助金额:$43.21万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8462272
-
项目类别:
-
资助金额:$51.28万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Acute and Chronic In vivo Effects of Engineered Nanomaterials
-
批准号:8136863
-
项目类别:
-
资助金额:$43.54万
-
财政年份:2010
-
负责人:Terry Gordon
-
依托单位:
Genetic Susceptibility to Chronic Beryllium Disease
-
批准号:7028968
-
项目类别:
-
资助金额:$31.32万
-
财政年份:2003
-
负责人:Terry Gordon
-
依托单位:
Genetic Susceptibility to Chronic Beryllium Disease
-
批准号:6734738
-
项目类别:
-
资助金额:$31.76万
-
财政年份:2003
-
负责人:Terry Gordon
-
依托单位:
Genetic Susceptibility to Chronic Beryllium Disease
-
批准号:6611501
-
项目类别:
-
资助金额:$30.76万
-
财政年份:2003
-
负责人:Terry Gordon
-
依托单位:
Genetic Susceptibility to Chronic Beryllium Disease
-
批准号:6847091
-
项目类别:
-
资助金额:$32.11万
-
财政年份:2003
-
负责人:Terry Gordon
-
依托单位:
Training Program in Environmental Toxicology
-
批准号:10206862
-
项目类别:
-
资助金额:$29.45万
-
财政年份:1999
-
负责人:Terry Gordon
-
依托单位:
Training Program in Environmental Toxicology
-
批准号:9307823
-
项目类别:
-
资助金额:$18.64万
-
财政年份:1999
-
负责人:Terry Gordon
-
依托单位:
Training Program in Environmental Medicine
-
批准号:8296293
-
项目类别:
-
资助金额:$25.57万
-
财政年份:1999
-
负责人:Terry Gordon
-
依托单位:
Training Program in Environmental Medicine
-
批准号:8102933
-
项目类别:
-
资助金额:$14.26万
-
财政年份:1999
-
负责人:Terry Gordon
-
依托单位:
海外基金