Strategies for Setting Occupational Exposure Limits for Engineered Nanomaterials

设定工程纳米材料职业接触限值的策略

• 批准号: 8396928
• 负责人: Terry Gordon
• 金额: $ 1.97万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8396928
• 关键词: Strategies; Setting; Occupational; Exposure; Limits

DESCRIPTION (provided by applicant): Although the study of the toxicity and risks associated with occupational exposure to nanomaterials is moving forward and numerous meetings have addressed the toxicity and risk of exposure to nanoparticles, no meetings have solely addressed the difficulties in setting occupational exposure limits (OELs) for nanomaterials. The proposed meeting will bring together stakeholders from industry, government agencies, non-government organizations, and academics to focus their talents and expertise on developing strategies for assessing safe workplace exposure levels for nanoparticles. We will hold the meeting at George Washington University (GWU) in Washington, DC. GWU is an academic center of excellence that is nationally renowned for research in occupational health and environmental and occupational health policy issues. There will be co- sponsorship by NYU School of Medicine, ACC, GWU, Ferro Corporation, and the 3M Corporation. The goal of the proposed meeting is to bring together and facilitate discussion among key nanomaterial hygienists, risk assessors, and researchers, and it is anticipated that there will be 75 to 100 attendees. While the meeting will focus on nation-wide efforts to develop OELs for nanomaterials, 2 of the invited speakers, Drs. Pauluhn and Lansiedel, will provide a European perspective on OEL setting. The critical issues have been assigned approximately 1/2 day for presentations and discussions. Full participation of stakeholders, speakers, moderators, and audience is expected and appropriate time for questions, answers, and discussion has been allocated for each session. As a final product of the proposed meeting, a published report will include an overview of the workshop, areas of general consensus and disagreement, and areas needing further research. We anticipate that this report will become a 'state of the science' article with recommendations for the best approaches to developing OELs for diverse nanomaterials with varying degrees of support from toxicity data. PUBLIC HEALTH RELEVANCE: The proposed meeting will bring together stakeholders from industry, government agencies, non- government organizations, and academics to focus their talents and expertise on developing strategies for assessing safe workplace exposure levels for nanoparticles. The meeting will take place in Washington, DC and has a number of co-sponsors. Participation by stakeholders, speakers, and moderators will result in a published report that will provide a 'state of the science' approach (es) to developing safe exposure limits for workplace exposure to nanomaterials. )

描述（由申请人提供）：尽管与纳米材料职业暴露相关的毒性和风险研究正在向前推进，并且许多会议已经讨论了纳米颗粒暴露的毒性和风险，但没有会议单独讨论了设定纳米材料职业暴露限值（OEL）的困难。拟议的会议将汇集来自行业，政府机构，非政府组织和学术界的利益相关者，将他们的人才和专业知识集中在制定评估纳米颗粒安全工作场所暴露水平的战略上。我们将在华盛顿的乔治华盛顿大学（GWU）举行会议。GWU是一个卓越的学术中心，在职业健康和环境与职业健康政策问题的研究方面享誉全国。将有共同赞助的纽约大学医学院，行政协调会，GWU，铁公司，和3 m公司。拟议会议的目标是召集和促进关键纳米材料专家、风险评估人员和研究人员之间的讨论，预计将有75至100名与会者。虽然会议将重点关注全国范围内为纳米材料制定OEL的努力，但两位受邀演讲者Pauluhn博士和Lansiedel博士将提供欧洲对OEL设置的看法。关键问题被分配了大约1/2天的时间进行介绍和讨论。预计利益相关者、演讲者、主持人和观众将充分参与，并为每次会议分配了适当的提问、回答和讨论时间。作为拟议会议的最后产品，将发表一份报告，其中将包括研讨会概况、普遍共识和分歧领域以及需要进一步研究的领域。我们预计，这份报告将成为一个“国家的科学”的文章与建议的最佳方法，以开发不同的纳米材料与不同程度的支持毒性数据的OEL。 公共卫生关系：拟议中的会议将汇集来自行业、政府机构、非政府组织和学术界的利益相关者，将他们的才能和专业知识集中在制定评估纳米颗粒安全工作场所暴露水平的战略上。会议将在华盛顿举行，有一些共同赞助者。利益攸关方、发言人和主持人的参与将产生一份出版的报告，该报告将提供一种“科学现状”方法，以制定工作场所接触纳米材料的安全接触限值。)

项目成果

Workshop report: strategies for setting occupational exposure limits for engineered nanomaterials.

研讨会报告：设定工程纳米材料职业接触限值的策略。

• DOI: 10.1016/j.yrtph.2014.01.005
• 发表时间: 2014
• 期刊: Regulatory toxicology and pharmacology : RTP
• 作者: Gordon,StevenC;Butala,JohnH;Carter,JanetM;Elder,Alison;Gordon,Terry;Gray,George;Sayre,PhilipG;Schulte,PaulA;Tsai,CandaceS;West,Jay
• 通讯作者: West,Jay