2017 INTEREST Conference

抽象的。 联合国艾滋病规划署对全球艾滋病毒负担的最新估计是， 艾滋病毒感染者中有2550万人生活在撒哈拉以南非洲地区（UNAIDS Fact 表2016）。此外，每年70%的新感染病例发生在世界同一地区 （艾滋病规划署。艾滋病如何改变一切（2015）自2010年以来，艾滋病毒感染率下降了14%。 东部和南部非洲下降8%，西部和中部非洲下降8%，而艾滋病毒流行率继续上升， 随着越来越多的人获得抗逆转录病毒治疗，虽然治疗可能会有一个重要的 尽管它对减缓艾滋病毒传播的影响很大，但它本身并不能扭转这一流行病。艾滋病毒预防 仍然是遏制艾滋病毒蔓延的关键。联合国艾滋病规划署的90-90-90目标是到2020年为90%的人提供服务 艾滋病毒感染者知道他们的艾滋病毒状况，90%的人知道他们的艾滋病毒阳性状态是在 抗逆转录病毒治疗，90%的人在治疗中抑制了病毒载量（艾滋病规划署。快速- 轨道：到2030年消除艾滋病流行; 2014年）。非洲大陆目前的估计是29% 所有艾滋病毒感染者的病毒载量都受到了抑制。级联治疗的每一步都需要 密集的投资：扩大艾滋病毒检测的范围，以诊断艾滋病毒感染者，立即提供 抗逆转录病毒治疗，无论CD 4计数，并保留在有效的治疗，以实现病毒 镇压尽管有许多措施可以解决非洲的艾滋病毒疾病负担， 在培训当地医生和科学家进行诊断方面仍有许多工作要做， 艾滋病毒1感染者的治疗和管理，以及在循证医学方面， 公共卫生对策和执行科学，以确定最具成本效益的财政资源使用 和人力资源的问题。 2017年的兴趣会议，被称为“非洲CROI”，汇集了参与的科学家 在非洲资源有限的环境中进行艾滋病毒治疗、发病机制和预防研究， 关键的发现，促进合作，并在多个领域和许多 大洲一个由艾滋病毒领域的著名国际专家组成的小组发起了这一重点 2007年在非洲举行国际科学会议。自那时以来，已成功举办了10次年会， 在乌干达、塞内加尔（两次）、赞比亚（两次）、莫桑比克、坦桑尼亚、肯尼亚、津巴布韦和 喀麦隆.会议的规划和组织由阿姆斯特丹全球研究所监督。 健康与发展。Catherine Hankins医学博士主持Interest的国际组织 国际奥委会委员会（IOC），也是Interest的科学主席。2017年当地主席兴趣 会议是山姆Phiri医学博士，灯塔信托基金，马拉维主任。 2017年国际兴趣会议的组织者将追求以下目标： 1)展示艾滋病毒发病机制、诊断、 治疗和预防HIV-1感染。 2)继续促进建立一个非洲医生和科学家社区， 讨论实施管理HIV-1感染者的当地解决方案 感染和预防艾滋病毒传播。 ! !

Abstract. The most recent UNAIDS estimates of the global burden of HIV are that 36.7 million people are living with HIV-1 infection worldwide and 25.5 million of them live in sub-Saharan Africa (UNAIDS Fact Sheet 2016). Moreover, 70% of new infections annually are occurring in the same region of the world (UNAIDS. How AIDS Changed Everything; 2015). Since 2010, HIV incidence has declined by 14% in eastern and southern Africa and by 8% in western and central Africa, while HIV prevalence continues to rise as more people access antiretroviral treatment. Although treatment is likely having an important impact on slowing HIV transmission, alone it will not turn the epidemic on its head. HIV prevention remains critical to stem the tide of HIV. The UNAIDS 90-90-90 targets for 2020 aim for 90% of people living with HIV knowing their HIV status, 90% of people who know their HIV-positive status being on antiretroviral treatment, and 90% of people on treatment having suppressed virus loads (UNAIDS. Fast- track: ending the AIDS epidemic by 2030; 2014). Current estimates for the African continent are that 29% of all those living with HIV have suppressed viral loads. Every step of the treatment cascade needs intensive investment: scaling up HIV testing access to diagnose those living with HIV, an immediate offer of antiretroviral treatment regardless of CD4 count, and retention in effective treatment to achieve viral suppression. Although there are many measures in place to tackle the HIV disease burden in Africa there remains much work to do in terms of training local physicians and scientists in regard to diagnosis, treatment, and management of individuals with HIV-1 infection, as well as in respect to evidence-informed public health responses and implementation science to determine the most cost-effective use of financial and human resources. The 2017 INTEREST Conference, known as the ‘African CROI’ brings together scientists involved in HIV treatment, pathogenesis, and prevention research in resource-limited settings in Africa to share pivotal findings, promote collaboration, and transfer experiences across several fields and many continents. A prominent group of international experts in the field of HIV launched this focused international scientific meeting in Africa in 2007. Since then, 10 successful annual meetings have been convened in Uganda, Senegal (twice), Zambia (twice), Mozambique, Tanzania, Kenya, Zimbabwe, and Cameroon. Planning and organization of the conference is overseen by the Amsterdam Institute of Global Health and Development. Catherine Hankins MD PhD chairs INTEREST’s international organizing committee (IOC) and is the Scientific Chair of INTEREST. The Local Chair for 2017 INTEREST conference is Sam Phiri MD PhD, Director of the Lighthouse Trust, Malawi. The organizers of the 2017 INTEREST Conference will pursue the following objectives: 1) To showcase cutting-edge knowledge in the fields of HIV pathogenesis, diagnosis, treatment, and prevention of HIV-1 infection. 2) To continue to foster the building of a community of African physicians and scientists who discuss implementing local solutions for the management of patients living with HIV-1 infection and for the prevention of HIV transmission. ! !