14th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST)

第14届国际艾滋病毒治疗、发病机制和预防研究会议（INTEREST）

• 批准号: 10012378
• 负责人: Guido Ferrari
• 金额: $ 4.5万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-06 至 2021-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10012378
• 关键词: AIDS prevention; Acquired Immunodeficiency Syndrome; Adherence; Adolescent; Adult; Advisory Committees; Africa; Africa South of the Sahara; African; Age; Award; CD4 Lymphocyte Count; Career Choice; Cessation of life; Child; Clinical; Collaborations; Communities; Development; Diagnosis; Doctor of Philosophy; Early Diagnosis; Ebola; Elderly; Ensure; Epidemic; Event; Fostering; Future; Goals; HIV; HIV Infections; HIV Seropositivity; HIV diagnosis; HIV-1; HIV/TB; Health; Health Care Research; Health Policy; Health Services; Health financing; Hepatitis C; Human Resources; Human immunodeficiency virus test; Individual; Infection; Institutes; International; Investments; Knowledge; Leadership; Leprosy; Malaria; Measures; Oral; Outcome; Pathogenesis; Physicians; Prevention; Prevention Research; Prevention strategy; Public Health; Ramp; Reporting; Research; Research Personnel; Resources; Science; Scientist; Social Work; Training; Travel; Treatment Protocols; Treatment Step; Tuberculosis; Uganda; Viral; Viral Drug Resistance; Viral Load result; Vocational Guidance; Work; Youth; aged; antiretroviral therapy; base; behavioral/social science; career development; clinical care; comorbidity; cost; cost effective; demographics; disparity reduction; effective therapy; evidence base; experience; fight against; girls; global health; implementation science; mHealth; meetings; men; mortality; novel; pandemic disease; pathogen; peer; prevent; programs; research and development; response; scale up; stem; symposium; transmission process; treatment strategy; young woman

Abstract. The most recent UNAIDS estimates of the global burden of HIV are that 36.9 million people are living with HIV-1 infection worldwide, with 69.4% of these residing in sub-Saharan Africa. Markedly, three in four new infections in sub-Saharan Africa are among girls aged 15–19 years and young women aged 15–24 years are twice as likely to be living with HIV than men that age. Further, a striking difference exists between the east/southern and the west/central regions of sub-Saharan Africa, with reductions in AIDS-related deaths since 2010 of 42% and 24%, respectively. Clearly, much work remains in terms of training local physicians and scientists in the diagnosis, treatment, and management of individuals with HIV-1 infection; conducting implementation science to determine the most cost-effective use of financial and human resources; and ensuring evidence-informed public health policy and programming to reduce disparities in the AIDS response across Africa’s sub-regions. Despite treatment likely having contributed to slowing HIV transmission, HIV prevention remains critical to stem the tide of HIV. In fact, a second AIDS pandemic in the next 12 years is predicted due to 1) changing demographics in Africa with increasing numbers of youth, 2) increasing transmitted viral drug resistance, and 3) increased cost and limited availability of 2nd and 3rd line treatment regimens. Taken together, these factors suggest that the total number of people living with AIDS may increase by 2 million/year to reach a staggering 50 million worldwide by 2030. Since 2007, 13 successful annual INTEREST Conferences, known as the ‘African CROI’, have brought together scientists involved in HIV diagnosis and treatment, pathogenesis, and prevention research in resource-limited settings in Africa to share pivotal findings, promote collaboration, and transfer experiences across several fields and many continents. Planning and organization of the 2020 INTEREST Conference will be overseen by the Amsterdam Institute of Global Health and Development. Catherine Hankins MD PhD chairs INTEREST’s International Conference Committee (ICC) and is the Scientific Chair of INTEREST. The organizers of the 2020 INTEREST Conference will pursue the following objectives: 1) To provide cutting-edge knowledge in the fields of diagnosis and treatment, pathogenesis, and prevention of HIV-1 for adults, including the elderly; adolescents; and children living with HIV in Africa, in order to contribute to achieving the 90-90-90 viral suppression goal and to preventing a second great pandemic. 2) To foster new research interactions among leading investigators and those who represent the potential future scientific leadership for health care and research on the African continent.

摘要。