Cancer Therapy & Research Center at UTHSCSA

描述（由申请人提供）：癌症治疗与研究中心（CTRC）寻求1991年最初授予的NCI称号的更新。CTRC是南德克萨斯州唯一的学术癌症中心，服务于一个以西班牙裔为主的大型集水区。CTRC的使命是通过最高质量的癌症护理，旨在降低癌症发病率和死亡率的突破性研究，未来癌症科学家和临床医生的教育以及针对我们独特人群的癌症预防计划来减轻南德克萨斯州的癌症负担。CTRC主任Ian M. Thompson, Jr.博士和CTRC高级领导组织了一个由来自UTHSCSA两所学校和11个部门的78名癌症研究人员（基础和临床）组成的跨学科小组，分为三个项目：癌症发展和进展（CDP），实验和发展治疗（EDT）和癌症预防和人口科学（CPPS）。这些项目由7个共享资源支持：基因组学，下一代测序，大分子结构和相互作用，质谱，流式细胞术，光学成像和生物统计学。CTRC还要求支持其临床试验办公室（CTO）。自2008年以来，CTO的改进导致了应计项目的增加，但重要的是，介入试验的应计项目从2008年的394项增加到2012年的796项。CTRC还努力服务于它的集水区，这一事实表明，参加介入治疗临床试验的患者中有46%是西班牙裔。

DESCRIPTION (provided by applicant): The Cancer Therapy & Research Center (CTRC) seeks renewal of its NCI designation originally awarded in 1991. The only academic Cancer Center in South Texas, the CTRC serves a large and predominantly Hispanic catchment area. The mission of the CTRC is to reduce the cancer burden in South Texas through the highest quality cancer care, ground-breaking research aimed at reducing the incidence and mortality of cancer, education of future cancer scientists and clinicians, and cancer prevention programs focused on our unique population. Dr. Ian M. Thompson, Jr., Director of the CTRC and the CTRC Senior Leaders have organized an interdisciplinary group of 78 cancer researchers (both basic and clinical) from two schools and 11 Departments within the UTHSCSA into three Programs: Cancer Development and Progression (CDP), Experimental and Developmental Therapeutics (EDT) and Cancer Prevention and Population Science (CPPS). These Programs are supported by 7 Shared Resources: Genomics, Next Generation Sequencing, Macromolecular Structure and Interactions, Mass Spectrometry, Flow Cytometry, Optical Imaging and Biostatistics. The CTRC also requests support for its Clinical Trials Office (CTO). Since 2008, improvements in the CTO have led to an increase in accruals, but importantly, an increase in interventional trials from 394 accruals in 2008 to 796 accruals in 2012. The CTRC has also made efforts to serve its catchment area illustrated by the fact that 46% of patients enrolled in interventional therapeutic clinical trials are Hispanic. Today, the UTHSCSA has $30,681,682M in annual total extramural research funding; a 74% increase from 2008. Of that $8,948,865M is from the NCI. Since 2008, 31 cancer-related clinical and research faculty have been recruited to the CTRC. All but one of the CTRC Senior Leaders are new since 2008. In 2011, UTHSCSA added 25,000 sq.ft. of CTRC-designated space in the new South Texas Research Facility, increasing CTRC-designated space to 285,193 sq.ft. The CTRC also invested in administrative infrastructure to support the CCSG and the research enterprise at the CTRC, in pilot funds for transdisciplinary research, and infrastructure to support clinical trials. The growth of the CTRC over the past 5 years is evidence of the commitment of the Center and its members to cancer research. Our members continue to make significant contributions to the cancer research field and develop novel approaches to prevent, diagnose and treat cancer, all with a continual focus on the predominantly Hispanic catchment area we serve.