Cancer Therapy & Research Center at UTHSCSA

癌症治疗

• 批准号: 9334720
• 负责人: Ruben A. Mesa
• 金额: $ 209.3万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2019-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9334720
• 关键词: Award; Biometry; Cancer Burden; Cancer Center; Cancer Center Support Grant; Catchment Area; Clinical; Clinical Research; Clinical Trials; Communities; Development; Developmental Therapeutics Program; Diagnosis; Enrollment; Extramural Activities; Flow Cytometry; Funding; Future; Genomics Shared Resource; Goals; Growth; Hispanics; Incidence; Intervention Trial; Investigational Therapies; Malignant Neoplasms; Mass Spectrum Analysis; Mission; Molecular Structure; NCI Center for Cancer Research; Patients; Population; Population Sciences; Prevention program; Recruitment Activity; Research; Research Infrastructure; Research Personnel; Resources; Schools; Scientist; South Texas; Therapeutic Clinical Trial; Therapeutic Intervention; Translations; anticancer research; bench to bedside; cancer care; cancer education; cancer prevention; cancer therapy; faculty research; interdisciplinary collaboration; member; mortality; next generation sequencing; novel strategies; optical imaging; prevent; programs; research facility; square foot

DESCRIPTION (provided by applicant): The Cancer Therapy & Research Center (CTRC) seeks renewal of its NCI designation originally awarded in 1991. The only academic Cancer Center in South Texas, the CTRC serves a large and predominantly Hispanic catchment area. The mission of the CTRC is to reduce the cancer burden in South Texas through the highest quality cancer care, ground-breaking research aimed at reducing the incidence and mortality of cancer, education of future cancer scientists and clinicians, and cancer prevention programs focused on our unique population. Dr. Ian M. Thompson, Jr., Director of the CTRC and the CTRC Senior Leaders have organized an interdisciplinary group of 78 cancer researchers (both basic and clinical) from two schools and 11 Departments within the UTHSCSA into three Programs: Cancer Development and Progression (CDP), Experimental and Developmental Therapeutics (EDT) and Cancer Prevention and Population Science (CPPS). These Programs are supported by 7 Shared Resources: Genomics, Next Generation Sequencing, Macromolecular Structure and Interactions, Mass Spectrometry, Flow Cytometry, Optical Imaging and Biostatistics. The CTRC also requests support for its Clinical Trials Office (CTO). Since 2008, improvements in the CTO have led to an increase in accruals, but importantly, an increase in interventional trials from 394 accruals in 2008 to 796 accruals in 2012. The CTRC has also made efforts to serve its catchment area illustrated by the fact that 46% of patients enrolled in interventional therapeutic clinical trials are Hispanic. Today, the UTHSCSA has $30,681,682M in annual total extramural research funding; a 74% increase from 2008. Of that $8,948,865M is from the NCI. Since 2008, 31 cancer-related clinical and research faculty have been recruited to the CTRC. All but one of the CTRC Senior Leaders are new since 2008. In 2011, UTHSCSA added 25,000 sq.ft. of CTRC-designated space in the new South Texas Research Facility, increasing CTRC-designated space to 285,193 sq.ft. The CTRC also invested in administrative infrastructure to support the CCSG and the research enterprise at the CTRC, in pilot funds for transdisciplinary research, and infrastructure to support clinical trials. The growth of the CTRC over the past 5 years is evidence of the commitment of the Center and its members to cancer research. Our members continue to make significant contributions to the cancer research field and develop novel approaches to prevent, diagnose and treat cancer, all with a continual focus on the predominantly Hispanic catchment area we serve.

描述(由申请人提供)：癌症治疗与研究中心(CTRC)寻求更新其最初于1991年授予的NCI称号。作为南得克萨斯州唯一的学术癌症中心，CTRC服务于一个以西班牙裔为主的大范围集水区。CTRC的使命是通过最高质量的癌症护理、旨在降低癌症发病率和死亡率的开创性研究、对未来癌症科学家和临床医生的教育，以及专注于我们独特人口的癌症预防计划，来减轻德克萨斯州南部的癌症负担。美国癌症研究中心主任小伊恩·M·汤普森博士和癌症研究中心高级领导组织了一个由来自UTHSCSA内两所学校和11个科室的78名癌症研究人员(基础和临床)组成的跨学科小组，分成三个项目：癌症发展和进展(CDP)、实验和发育治疗(EDT)以及癌症预防和人口科学(CPPS)。这些项目得到了7个共享资源的支持：基因组学、下一代测序、大分子结构和相互作用、质谱学、流式细胞术、光学成像和生物统计学。CTRC还请求为其临床试验办公室(CTO)提供支持。自2008年以来，CTO的改进导致了应计项目的增加，但重要的是，干预试验的应计项目从2008年的394项增加到2012年的796项。CTRC还努力服务于其覆盖地区，参加介入治疗临床试验的患者中有46%是西班牙裔。 今天，UTHSCSA每年的校外研究资金总额为306.81682亿美元，比2008年增长了74%。在这89.488.65亿美元中，来自NCI。自2008年以来，CTRC已招聘了31名与癌症相关的临床和研究人员。除一名外，所有反恐委员会高级领导人都是2008年以来的新人。2011年，UTHSCSA增加了25,000平方英尺。在新的南得克萨斯研究设施中，增加了CTRC指定的空间，将CTRC指定的空间增加到285 193平方英尺。CTRC还投资了行政基础设施，以支持CCSG和CTRC的研究企业，投资于跨学科研究的试点基金，以及支持临床试验的基础设施。CTRC在过去五年中的发展证明了该中心及其成员对癌症研究的承诺。我们的成员继续为癌症研究领域做出重大贡献，并开发预防、诊断和治疗癌症的新方法，所有这些都继续专注于我们服务的主要拉美裔聚集区。