Biology of Prostate Cancer

前列腺癌生物学

基本信息

  • 批准号:
    9282702
  • 负责人:
  • 金额:
    $ 2.71万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-06-01 至 2018-05-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY (See instructions): The Blology of Prostate Cancer (BPC) Program at the Kimmel Cancer Center (KCC) is a new program that emanated from the former Endocrine Mechanisms and Hormone Action in Cancer (EMHAC) Program, and represents the section of the EHMAC that focused on prostate cancer. From 2007 to 2011, EMHAC increased the number of highly productive investigators studying either breast/gynecological malignancies or prostate/genitourinary cancers, allow^ing the strategic creation of the BPC program in 2011. During this same interval, the Greater Philadelphia Prostate Cancer Working Group was founded by new recruit Dr. Karen Knudsen, and served as a basis for development of the BPC and the associated consortium. The BPC program consists of 18 investigators from 10 departments and 3 institutions. The Program currently brings in $2.3 million/year in total costs from NCI grants and $4.1 million/year total peer-reviewed costs. Since 2007, the program produced 343 publications of which, 10% of publications were intra-programmatic, 43% were inter-programmatic, and 5% were both inter- and intra-programmatic. Dr. Karen E. Knudsen (Leader) is an accomplished investigator with expertise in basic and translational prostate cancer research. Dr. Gomella, the Co-Leader (TJU) of BPC, provides clinical expertise in genitourinary malignancies. Dr. Fatatis the Co-leader (Drexel University) of BPC is an accomplished physician scientist with expertise in cancer metastasis at the basic and clinical level. He will play a pivotal role integrating Drexel University and TJU cancer researchers in the BPC Program. The goals of the BPC program are to leverage the significant translational and clinical expertise in genitourinary oncology (most especially with regard to prostate cancer) with the intent to: delineate the mechanisms that underpin prostate cancer development and progression, identify novel means to treat advanced disease, and improve disease management by translating these findings into clinical trials. Studies within the program are directed at developing new strategies for effective detection,diagnosis,and cure. Specific aims of this program are to;1. Develop new strategies for prevention, detection, and subtyping of early stage prostate malignancies; 2. Define the impact of hormone action in malignant disease development and prostate cancer progression; 3. Develop novel treatment strategies for prostate malignancies;4. Develop predictive markers for rational therapy delivery.
项目概述(见说明):

项目成果

期刊论文数量(0)
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KAREN E KNUDSEN其他文献

KAREN E KNUDSEN的其他文献

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{{ truncateString('KAREN E KNUDSEN', 18)}}的其他基金

Protocol Review and Monitoring System
方案审查和监控系统
  • 批准号:
    9282719
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Targeting Cell Cycle Alterations to Improve Treatment for Advanced Prostate Cancer
针对细胞周期改变改善晚期前列腺癌的治疗
  • 批准号:
    9343456
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Gastrointestinal Cancer
胃肠癌
  • 批准号:
    9282706
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Cancer Cell Biology and Signaling
癌细胞生物学和信号转导
  • 批准号:
    9282701
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Data & Safety Monitoring
数据
  • 批准号:
    9282721
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Facilities
设施
  • 批准号:
    9282726
  • 财政年份:
    2017
  • 资助金额:
    $ 2.71万
  • 项目类别:
Senior Leadership
高层领导
  • 批准号:
    9071340
  • 财政年份:
    2016
  • 资助金额:
    $ 2.71万
  • 项目类别:
Protocol Review and Monitoring System
方案审查和监控系统
  • 批准号:
    9071336
  • 财政年份:
    2016
  • 资助金额:
    $ 2.71万
  • 项目类别:
Translational Research
转化研究
  • 批准号:
    9071331
  • 财政年份:
    2016
  • 资助金额:
    $ 2.71万
  • 项目类别:
Molecular Biology and Genetics Program
分子生物学和遗传学计划
  • 批准号:
    9071324
  • 财政年份:
    2016
  • 资助金额:
    $ 2.71万
  • 项目类别:

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