Development of a Tailored HIV Prevention Intervention for Young Men

 描述(由申请人提供)：青年男男性行为者(18-24岁)中新的艾滋病毒/艾滋病病例卷土重来，突显了为青年男性同性恋者制定具有文化和发展知识的艾滋病毒/艾滋病方案的重要性。我们建议开发和试点一种名为Meet-ME的量身定做的、基于网络的干预措施，该干预措施侧重于根据单身YMSM的关系期望和寻找伴侣的行为传递艾滋病毒/艾滋病预防信息。为了最大限度地提高干预的吸引力和适宜性，我们将召集一个青年咨询委员会(YAB)，在干预发展过程中提供见解和反馈。利用迭代的设计和开发过程，我们将制定量身定制的信息，使YMSM的关系经验和愿望与艾滋病毒/艾滋病预防战略保持一致。然后，我们将设计和开发Meet-ME量身定制的在线预防干预措施，以及注意控制非定制艾滋病毒/艾滋病预防(NTHP)比较干预措施。在开发了这两种干预措施之后，我们将使用可用性测试程序来收集初步数据 从16个YMSM对建议干预措施的设计和可接受性。在启动一项小型试点随机对照试验(RCT)之前，将在干预措施中添加建议的更改。试验性随机对照试验将比较Meet-ME(N=120)和NTHP(N=60)，以评估干预的可行性和可接受性，并收集初步行为数据，为后续应用提供信息。评估将在30天、60天和90天后收集。具体目标包括：(1)制定专门的(Meet-ME)和非定制的(NTHP)艾滋病毒/艾滋病预防干预措施，重点是解决单身基督教男同性恋者(18-24岁)中的艾滋病毒/艾滋病危险行为；(2)收集关于Meet-ME(N=16)的可行性、可接受性和干预内容的初步数据，为小型试点随机对照试验做准备；(3)与NTHP(N=60)干预措施相比，实施改进的Meet-ME(N=120)干预的小规模试点RCT，以评估其可行性和可接受性，并收集在减少性危险行为方面的初步有效结果。

 DESCRIPTION (provided by applicant): A resurgence of new HIV/AIDS cases among young men who have sex with men (YMSM; ages 18-24) underscores the importance of developing culturally and developmentally informed HIV/AIDS programs for YMSM. We propose to develop and pilot test a tailored, web-based intervention called MEET-ME that focuses on delivering HIV/AIDS prevention messages based on single YMSMs' relationship expectations and partner- seeking behaviors. To maximize intervention appeal and appropriateness, we will convene a youth advisory board (YAB) to provide insight and feedback during the intervention development process. Using an iterative design and development process, we will develop tailored messages that align YMSM's relationship experiences and desires with HIV/AIDS prevention strategies. We will then design and develop the MEET-ME tailored online prevention intervention, as well as an attention-control non-tailored HIV/AIDS prevention (NTHP) comparison intervention. After developing both interventions, we will use usability testing procedures to collect preliminary data from 16 YMSM on the proposed intervention's design and acceptability. Recommended changes will be added to the intervention prior to launching a small pilot randomized controlled trial (RCT). The pilot RCT will compare MEET-ME (N=120) to NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary behavioral data to inform a subsequent application. Assessments will be collected at 30, 60, and 90 days follow-up. Specific Aims include: (1) To develop a tailored (MEET-ME) and non-tailored (NTHP) HIV/AIDS prevention intervention focused on addressing HIV/AIDS risk behaviors among single YMSM (ages 18-24); (2) To collect preliminary data on the feasibility, acceptability, and intervention content of the MEET-ME (N=16) in preparation for a small pilot RCT; and, (3) To implement a small pilot RCT of the refined MEET-ME (N=120) as compared to the NTHP (N=60) intervention, in order to evaluate its feasibility and acceptability and gather preliminary efficac results in reducing sexual risk behaviors.