Development of a Tailored HIV Prevention Intervention for Young Men

 描述（由申请人提供）：与男性发生性关系的年轻男性（YMSM;年龄18-24岁）中新的艾滋病毒/艾滋病病例的复苏强调了为YMSM制定文化和发展知情的艾滋病毒/艾滋病计划的重要性。我们建议开发和试点测试量身定制的，基于网络的干预称为MEET-ME，重点是提供艾滋病毒/艾滋病预防信息的基础上，单YMSM的关系期望和合作伙伴寻求行为。为了最大限度地提高干预措施的吸引力和适当性，我们将召集一个青年咨询委员会，在干预措施的制定过程中提供见解和反馈。使用一个迭代的设计和开发过程，我们将开发定制的信息，使YMSM的关系经验和愿望与艾滋病毒/艾滋病预防战略相一致。然后，我们将设计和开发MEET-ME量身定制的在线预防干预，以及注意力控制非量身定制的艾滋病毒/艾滋病预防（NTHP）比较干预。在开发了这两种干预措施之后，我们将使用可用性测试程序来收集初步数据 从16 YMSM建议的干预措施的设计和可接受性。在启动一项小型试点随机对照试验（RCT）之前，将对干预措施进行建议性变更。试点RCT将比较MEET-ME（N=120）和NTHP（N=60），以评估干预的可行性和可接受性，并收集初步的行为数据，为后续应用提供信息。将在30、60和90天随访时收集评估结果。具体目标包括：（1）针对单身男同性恋者的艾滋病毒/艾滋病危险行为，制定量身定制的（MEET-ME）和非量身定制的（NTHP）艾滋病毒/艾滋病预防干预措施（2）收集MEET-ME（N=16）可行性、可接受性和干预内容的初步数据，为小型试点RCT做准备;（3）对MEET-ME（120例）和NTHP（60例）进行小规模随机对照试验，评价MEET-ME干预的可行性和可接受性，并收集其减少危险性行为的初步效果。

 DESCRIPTION (provided by applicant): A resurgence of new HIV/AIDS cases among young men who have sex with men (YMSM; ages 18-24) underscores the importance of developing culturally and developmentally informed HIV/AIDS programs for YMSM. We propose to develop and pilot test a tailored, web-based intervention called MEET-ME that focuses on delivering HIV/AIDS prevention messages based on single YMSMs' relationship expectations and partner- seeking behaviors. To maximize intervention appeal and appropriateness, we will convene a youth advisory board (YAB) to provide insight and feedback during the intervention development process. Using an iterative design and development process, we will develop tailored messages that align YMSM's relationship experiences and desires with HIV/AIDS prevention strategies. We will then design and develop the MEET-ME tailored online prevention intervention, as well as an attention-control non-tailored HIV/AIDS prevention (NTHP) comparison intervention. After developing both interventions, we will use usability testing procedures to collect preliminary data from 16 YMSM on the proposed intervention's design and acceptability. Recommended changes will be added to the intervention prior to launching a small pilot randomized controlled trial (RCT). The pilot RCT will compare MEET-ME (N=120) to NTHP (N=60) to assess intervention feasibility and acceptability, and gather preliminary behavioral data to inform a subsequent application. Assessments will be collected at 30, 60, and 90 days follow-up. Specific Aims include: (1) To develop a tailored (MEET-ME) and non-tailored (NTHP) HIV/AIDS prevention intervention focused on addressing HIV/AIDS risk behaviors among single YMSM (ages 18-24); (2) To collect preliminary data on the feasibility, acceptability, and intervention content of the MEET-ME (N=16) in preparation for a small pilot RCT; and, (3) To implement a small pilot RCT of the refined MEET-ME (N=120) as compared to the NTHP (N=60) intervention, in order to evaluate its feasibility and acceptability and gather preliminary efficac results in reducing sexual risk behaviors.