Exploratory-Project 1
探索性项目 1
基本信息
- 批准号:10487459
- 负责人:
- 金额:$ 28.86万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-09-15 至 2026-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAdolescentAdoptionAdultAffectAgeBehaviorBehavioral MechanismsBisexualCaringClinicalDataDevelopmentDiscriminationEnsureEvaluationEvidence based interventionFamilyFeeling suicidalFemaleFriendsFutureGaysGeneral PopulationGoalsHIV prevention trialHealthHeterosexualsIndividualInterventionLearningLesbian Gay Bisexual Transgender QueerLifeMental HealthModelingOutcomeParticipantPersonsPhiladelphiaPredictive FactorProtocols documentationRandomizedReach Effectiveness Adoption Implementation and MaintenanceRecording of previous eventsReportingResearchResourcesRiskRisk FactorsSafetySame-sexSamplingSeriesSexualitySocial EnvironmentSocial isolationSocial supportSuicideSuicide attemptSuicide preventionTestingThinkingTimeTrainingYouthagedarmbasebiopsychosocialclinically significantcopingdepressive symptomsdesigneffectiveness implementation studyefficacy outcomesefficacy trialemerging adultemerging adulthoodethnic diversityevidence baseexperiencehigh riskimplementation frameworkimplementation interventionimplementation outcomesimplementation researchimprovedinnovationmarginalized populationmenmobile applicationmotivational enhancement therapypeer coachingpeer supportpilot testpopulation basedprimary outcomeprogramsprospectiveracial and ethnicrecruitreducing suicidesecondary outcomesexual minorityskillssocial stigmastressorsuicidalsuicidal behaviorsuicidal risktelehealthtreatment armwillingnessyoung man
项目摘要
Emerging adult gay, bisexual, and same-sex attracted men (EAGBM; ages 18-24) are vulnerable to unique
sexuality-related stressors that increase risk for suicidal ideation and behaviors. Unique risk factors predict
suicidal ideation and attempts in EAGBM, yet there are few targeted interventions to reduce suicide risk in
EAGBM by improving social support, coping, and positive affect. While evidence-based interventions like the
safety planning intervention (SPI) significantly reduce suicide risk, research indicates that individuals struggle to
use the safety plan in suicidal crises. Thus, we propose to examine a mobile application (Supporting Transitions
to Adulthood and Reducing Suicide; STARS) that leverages peer mentoring and support to ensure that EAGBM
can implement their safety plan in times of crisis. We will use the ADAPT-ITT Model to adapt an online life skills
intervention to reduce suicidal ideation and behaviors among EAGBM. STARS will include suicide prevention
content, including safety planning and targeting positive affect, consider cultural factors that may impact the
efficacy of safety planning for EAGBM (e.g., access to LGBTQ+ safe spaces), and include supports that promote
use of a suicide safety plan. STARS peer mentors will also provide social support, reduce the impact of
discrimination, connect youth to safe spaces, and help them overcome obstacles to use their safety plan. Guided
by the RE-AIM implementation science framework, we then will pilot test STARS using a Type 1 Effectiveness-
Implementation Hybrid Design in a racially/ethnically diverse sample of EAGBM (n=60) living in Philadelphia who
report past-month suicidal ideation. Participants will be randomized to an in-person brief, evidence-based safety
planning protocol (Control arm) or to safety planning plus access to STARS (Intervention arm). We will follow
participants over six months, with evaluations at 2, 4, and 6 months. Consistent with our Type 1 design, we will
prioritize preliminary efficacy outcomes (suicidal ideation and behavior) and hypothesized mechanisms of
change (coping with discrimination, social support, positive affect) needed to estimate critical parameters for a
future trial as our primary outcomes. We also will assess key implementation indicators in both arms
(participants: willingness and adoption of safety plan intervention or STARS; staff: experiences adapting and
delivering the program) as secondary outcomes. Our Specific Aims are (1) To conduct a systematic suicide
prevention adaptation of iREACH (“STARS”) that incorporates safety planning content and targets coping, social
support, and positive affect using the ADAPT-ITT framework; (2) To examine preliminary efficacy (suicidal
ideation and behaviors) and mechanisms of action of STARS, relative to our control condition (safety planning
protocol alone), using a prospective RCT design, and (3) using RE-AIM metrics, to examine whether STARS
has preliminary evidence for impacting intervention implementation outcomes among EAGBM compared to the
control arm. This Exploratory Project will identify the potential clinical utility of STARS for suicide prevention in a
vulnerable, often marginalized, population based on key parameters needed to inform a future efficacy trial.
新兴的成年同性恋,双性恋和同性吸引的男人(EAGBM;年龄18-24)容易受到独特的
与性有关的压力源,增加自杀意念和行为的风险。独特的风险因素预测
EAGBM中的自杀意念和企图,但很少有针对性的干预措施,以减少自杀风险,
EAGBM通过改善社会支持,应对和积极影响。虽然基于证据的干预措施,如
安全规划干预(SPI)显著降低自杀风险,研究表明,个人努力
在自杀危机中使用安全计划。因此,我们建议检查一个移动的应用程序(支持转换
成年期和减少自杀; STARS),利用同伴指导和支持,以确保EAGBM
能在危机时刻实施安全计划我们将使用ADAPT-ITT模型来适应在线生活技能
干预以减少EAGBM中的自杀意念和行为。STARS将包括自杀预防
内容,包括安全规划和针对性的积极影响,考虑文化因素,可能会影响
EAGBM安全规划的有效性(例如,获得LGBTQ+安全空间),并包括促进
使用自杀安全计划。STARS同伴导师还将提供社会支持,减少
消除歧视,将青年与安全空间联系起来,帮助他们克服障碍,使用他们的安全计划。指导
根据RE-AIM实施科学框架,我们将使用1型有效性对STARS进行试点测试,
在居住在费城的EAGBM(n=60)的种族/民族多样化样本中实施混合设计,
报告上个月的自杀意念受试者将被随机分配到一个面对面的简短,基于证据的安全性
计划方案(对照组)或安全计划加STARS访问(干预组)。我们将遵循
参与者在六个月内,在第2,4和6个月进行评估。与我们的1型设计一致,我们将
优先考虑初步疗效结局(自杀意念和行为)和
估计关键参数所需的变化(应对歧视、社会支持、积极影响)
未来的试验作为我们的主要结果。我们还将评估两个部门的关键执行指标
(参与者:安全计划干预或STARS的意愿和采用;工作人员:适应和
作为次要成果。我们的具体目标是(1)进行系统性自杀
预防适应iREACH(“STARS”),其中包括安全规划内容和目标应对,社会
使用ADAPT-ITT框架的支持和积极影响;(2)检查初步疗效(自杀
思维和行为)和STARS的作用机制,相对于我们的控制条件(安全规划
方案单独),使用前瞻性RCT设计,和(3)使用RE-AIM指标,检查STARS是否
有初步证据表明,与
本探索性项目将确定STARS在预防自杀方面的潜在临床效用,
根据为未来疗效试验提供信息所需的关键参数,
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jose Arturo Bauermeister其他文献
Jose Arturo Bauermeister的其他文献
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{{ truncateString('Jose Arturo Bauermeister', 18)}}的其他基金
Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in Florida
扩大实施战略以改善佛罗里达州年轻 MSM 的诊断和预防支柱
- 批准号:
10469026 - 财政年份:2022
- 资助金额:
$ 28.86万 - 项目类别:
Scaling Up Implementation Strategies to Improve the DIAGNOSE and PREVENT Pillars for Young MSM in Florida
扩大实施战略以改善佛罗里达州年轻 MSM 的诊断和预防支柱
- 批准号:
10676873 - 财政年份:2022
- 资助金额:
$ 28.86万 - 项目类别:
Increasing engagement and improving HIV care outcomes via stigma reduction in an online social networking intervention among racially diverse young men who have sex with men and transgender women
通过在线社交网络干预减少男男性行为和跨性别女性的种族不同的年轻男性的耻辱感,提高参与度并改善艾滋病毒护理结果
- 批准号:
10372060 - 财政年份:2018
- 资助金额:
$ 28.86万 - 项目类别:
Increasing engagement and improving HIV care outcomes via stigma reduction in an online social networking intervention among racially diverse young men who have sex with men and transgender women
通过在线社交网络干预减少男男性行为和跨性别女性的种族不同的年轻男性的耻辱感,提高参与度并改善艾滋病毒护理结果
- 批准号:
9765398 - 财政年份:2018
- 资助金额:
$ 28.86万 - 项目类别:
Increasing engagement and improving HIV care outcomes via stigma reduction in an online social networking intervention among racially diverse young men who have sex with men and transgender women
通过在线社交网络干预减少男男性行为和跨性别女性的种族不同的年轻男性的耻辱感,提高参与度并改善艾滋病毒护理结果
- 批准号:
10360761 - 财政年份:2018
- 资助金额:
$ 28.86万 - 项目类别:
Development of a Tailored HIV Prevention Intervention for Young Men
为年轻男性制定量身定制的艾滋病毒预防干预措施
- 批准号:
9241441 - 财政年份:2016
- 资助金额:
$ 28.86万 - 项目类别:
Development of a Tailored HIV Prevention Intervention for Young Men
为年轻男性制定量身定制的艾滋病毒预防干预措施
- 批准号:
9274460 - 财政年份:2016
- 资助金额:
$ 28.86万 - 项目类别:
Optimizing HIV counseling testing and referral through an adaptive drug use intervention
通过适应性药物使用干预优化艾滋病毒咨询测试和转诊
- 批准号:
9053599 - 财政年份:2015
- 资助金额:
$ 28.86万 - 项目类别:
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