Multiple Chronic Conditions_Interdisciplinary Nurse Scientist Training

 描述（由申请人提供）：这是T32博士前和博士后培训计划的新申请，为从事多种慢性疾病人群职业的护士科学家提供跨学科研究培训。多种慢性疾病的共存对整体健康状况、功能能力和生活质量造成了复合负担。下一代护理科学家需要配备 知识和技能，以解决与解决跨翻译连续体的多种慢性病的研究相关的复杂现象的研究。需要使用多个研究领域的概念模型和方法，以及整合多个跨学科的观点，方法和分析水平。需要使用新的分析方法来检查多种慢性疾病和治疗效果的机制和相互作用，发病率的聚集以及已知混杂因素的影响。一支能够在患有多种慢性病的人群中进行研究的训练有素的研究人员骨干队伍将有助于减少我们社会中已知具有高多重发病率的弱势群体的健康风险，包括少数民族/族裔、年幼者和年老者以及残疾人。 为了加强研究人员的文化多样性，我们正在与两个少数民族服务机构合作：佛罗里达州农业和机械（A&M）护理学院，一所历史悠久的黑人大学，以及纽约市立大学（CUNY）雷曼学院和研究生院，一所西班牙裔服务机构。我们将招募少数民族学员从佛罗里达A&M和雷曼在纽约市立大学到我们的快车道BSN博士课程和博士后培训计划。 在我们过去和现有的T32成功的基础上，这个NRSA将在5年内支持8名博士前和9名博士后学员。我们已经加强了我们现有的计划，包括强调研究培训，更跨学科，鼓励早期职业调查人员使用NIH校内研究机会，需要介绍遗传学和基因-环境相互作用作为生物-社会背景，以了解多种慢性病，并提供适合纵向，多层次或滞后效应分析的统计方法的高级培训。

 DESCRIPTION (provided by applicant): This is a new application for a T32 predoctoral and postdoctoral training program to provide interdisciplinary research training for nurse scientists pursuing careers focused on populations with multiple chronic conditions. The co-existence of multiple chronic conditions confers a compounding burden on overall health status, functional ability, and quality of life. The next generation of nurse scientists needs to be equipped with the knowledge and skills required to tackle the study of the complex phenomena associated with research addressing multiple chronic conditions across the translational continuum. The use of conceptual models and methods from several fields of study is needed, as well as the integration of multiple interdisciplinary perspectives, methodologies, and levels of analyses. The use of new analytic methods is needed to examine mechanisms and interactions of multiple chronic conditions and treatment effects, the clustering of morbidities, and the influence of known confounders. A cadre of expertly trained researchers who can conduct research among and within populations with multiple chronic conditions will assist to reduce the health disparitie among vulnerable groups in our society known to have high multiple morbidity, including those of minority racial/ethnicity, the very young and the very old and those with disabilities. To enhance the cultural diversity of the research workforce, we are collaborating with two minority- serving institutions: Florida Agricultural and Mechanical (A&M) School of Nursing, a historically black university, and Lehman College and Graduate School at City University of New York (CUNY), a Hispanic- serving institution. We will recruit minority trainees from Florida A&M and Lehman at CUNY into our fast-track BSN to PhD program and postdoctoral training program. Building on the success of our past and existing T32, this NRSA will support 8 predoctoral and 9 postdoctoral trainees over 5 years. We have enhanced our existing program to include an emphasis on research training that is more interdisciplinary, encourages the use of NIH intramural research opportunities for early career investigators, requires an introduction to genetics and gene-environment interactions as biological- social context for understanding multiple chronic conditions, and provides advanced training in statistical methods appropriate for longitudinal, multi-level, or lagged effects analyses.