Multiple Chronic Conditions_Interdisciplinary Nurse Scientist Training

 描述(由申请人提供)：这是一个新的申请T32博士后和博士后培训计划，以提供跨学科的研究培训，护士科学家追求的职业重点是人口与多种慢性病。多种慢性病的并存给整体健康状况、功能能力和生活质量带来了复杂的负担。下一代护士科学家需要配备 解决与研究翻译连续体中的多种慢性病相关的复杂现象所需的知识和技能。需要使用几个研究领域的概念模型和方法，以及整合多个跨学科的视角、方法和分析水平。需要使用新的分析方法来检查多种慢性病和治疗效果的机制和相互作用，疾病的聚集性，以及已知混杂因素的影响。一支训练有素的研究人员队伍，能够在患有多种慢性病的人群中和在人群中开展研究，将有助于减少我国社会中已知具有较高多种发病率的弱势群体之间的健康差异，包括少数族裔、幼儿和老年人以及残疾人。为了增强研究队伍的文化多样性，我们正在与两家为少数族裔服务的机构合作：佛罗里达农业与机械(A&M)护理学院，一所历史上的黑人大学，以及雷曼学院和纽约城市大学研究生院(CUNY)，一家为拉美裔服务的机构。我们将从佛罗里达A&M和雷曼兄弟在CUNY招募少数族裔实习生加入我们的快速通道BSN到博士项目和博士后培训项目。在我们过去和现有T32成功的基础上，NRSA将在5年内支持8名博士后和9名博士后实习生。我们加强了我们现有的计划，包括强调更多跨学科的研究培训，鼓励为职业生涯早期的研究人员使用NIH内部研究机会，要求介绍遗传学和基因-环境相互作用作为了解多种慢性病的生物-社会背景，并提供适用于纵向、多水平或滞后效应分析的统计方法方面的高级培训。

 DESCRIPTION (provided by applicant): This is a new application for a T32 predoctoral and postdoctoral training program to provide interdisciplinary research training for nurse scientists pursuing careers focused on populations with multiple chronic conditions. The co-existence of multiple chronic conditions confers a compounding burden on overall health status, functional ability, and quality of life. The next generation of nurse scientists needs to be equipped with the knowledge and skills required to tackle the study of the complex phenomena associated with research addressing multiple chronic conditions across the translational continuum. The use of conceptual models and methods from several fields of study is needed, as well as the integration of multiple interdisciplinary perspectives, methodologies, and levels of analyses. The use of new analytic methods is needed to examine mechanisms and interactions of multiple chronic conditions and treatment effects, the clustering of morbidities, and the influence of known confounders. A cadre of expertly trained researchers who can conduct research among and within populations with multiple chronic conditions will assist to reduce the health disparitie among vulnerable groups in our society known to have high multiple morbidity, including those of minority racial/ethnicity, the very young and the very old and those with disabilities. To enhance the cultural diversity of the research workforce, we are collaborating with two minority- serving institutions: Florida Agricultural and Mechanical (A&M) School of Nursing, a historically black university, and Lehman College and Graduate School at City University of New York (CUNY), a Hispanic- serving institution. We will recruit minority trainees from Florida A&M and Lehman at CUNY into our fast-track BSN to PhD program and postdoctoral training program. Building on the success of our past and existing T32, this NRSA will support 8 predoctoral and 9 postdoctoral trainees over 5 years. We have enhanced our existing program to include an emphasis on research training that is more interdisciplinary, encourages the use of NIH intramural research opportunities for early career investigators, requires an introduction to genetics and gene-environment interactions as biological- social context for understanding multiple chronic conditions, and provides advanced training in statistical methods appropriate for longitudinal, multi-level, or lagged effects analyses.