A Mobile Intervention to Improve Uptake of PrEP for Southern Black MSM

提高南方黑人 MSM 对 PrEP 吸收率的移动干预

• 批准号: 9340915
• 负责人: LARRY K BROWN
• 金额: $ 25.87万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-16 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9340915
• 关键词: AIDS diagnosis; AIDS prevention; Address; Appointment; Appointments and Schedules; Attitude; Behavior; Behavioral; Caring; Centers for Disease Control and Prevention (U.S.); Clinic; Communities; Data; Eligibility Determination; Ensure; Guidelines; HIV; HIV Infections; HIV risk; HIV/STD; Health; Healthcare; Hearing; High Prevalence; Human immunodeficiency virus test; Individual; Internet; Intervention; Interview; Knowledge; Link; Medical center; Mississippi; Modeling; Motivation; Participant; Patients; Phonation; Pilot Projects; Prevention strategy; Randomized; Randomized Controlled Trials; Risk Behaviors; Services; Site; Telephone; Testing; Text; Time; Treatment Efficacy; United States; Universities; base; black men who have sex with men; comparative efficacy; cost effective; follow-up; improved; men who have sex with men; pre-exposure prophylaxis; skills; standard of care; uptake; web site

The uptake of Pre-Exposure Prophylaxis (PrEP) has been slow for young Black men who have sex with men (BMSM) living in the Southern United States. This is a significant issue because eight of the ten states with the highest rates of new HIV infections are located in the South. Jackson, MS (the site of this proposed project) has the second highest AIDS diagnosis rate in the nation, and the highest rate of HIV infection for young urban Black men who have sex with men. This study will develop and test an engaging, interactive, and cost effective mobile messaging intervention to improve linkage to PrEP care for BMSM (18-35 yrs) living in Jackson, MS. BMSM eligible for PrEP, receiving care at the University of Mississippi Medical Center STI/HIV testing clinics, will be texted interactive links to publicly available, online content about PrEP and HIV prevention. Links will be sent to PrEP eligible BMSM by 8- 16 interactive text messages over 4 weeks. The material used in the intervention will be consistent with the Information Motivation Behavior (IMB) Model and will address cultural and structural barriers to initiating PrEP care. Creation and adaptation of the Intervention (e.g. choosing which publicly available links to send) will occur from in-depth interviews (n = 30) with PrEP eligible BMSM who receive care in the STI/HIV testing clinics. A small randomized controlled study among 66 new participants in the clinics will examine the preliminary efficacy of the intervention compared to enhanced standard of care on attendance at a PrEP Services Appointment (the first step in initiating PrEP care). It is hypothesized that, compared to BMSM receiving enhanced standard of care, BMSM receiving the PrEP Mobile Messaging Intervention will show greater attendance at a PrEP Services Appointment and decreased HIV risk behavior at 4 and 16 weeks. Increased information, Black MSM seen at UMMC motivation, and behavioral skills STI/HIV testing clinics, who are for initiating PrEP care candidates for PrEP but do not start PrEP, receive 8-16 text Decrease structural barriers messages over 4 weeks with Decrease HIV/STI risk behaviors engaging links to PrEP and HIV prevention content. Attendance at PrEP Services Appointment

接触前预防（PrEP）的吸收对于与男性发生性关系的年轻黑人男性来说是缓慢的。 男性（BMSM）生活在美国南部。这是一个重要的问题，因为十个州中有八个州 艾滋病毒新感染率最高的地区位于南方。杰克逊，MS（该网站的建议 艾滋病诊断率全国第二高，艾滋病感染率全国最高。 与男性发生性关系的年轻城市黑人男性。这项研究将开发和测试一个引人入胜的，互动的， 具有成本效益的移动的信息干预，以改善与生活在以下地区的BMSM（18-35岁）的PrEP护理的联系： 杰克逊，MS. BMSM有资格接受PrEP，在密西西比医学中心STI/HIV大学接受治疗 测试诊所，将通过短信互动链接到公开的，关于PrEP和艾滋病毒的在线内容 预防链接将发送到PrEP合格的BMSM通过8- 16互动短信超过4周。的 干预中使用的材料将与信息动机行为（IMB）模型一致， 将解决启动PrEP护理的文化和结构性障碍。干预的创建和调整 (e.g.选择哪些公开可用的链接发送）将发生在深入访谈（n = 30）与PrEP 在性病/艾滋病毒检测诊所接受治疗的符合条件的BMSM。一项小型随机对照研究， 诊所的新参与者将检查干预措施的初步疗效， 在PrEP服务预约出席护理标准（启动PrEP护理的第一步）。是 我假设，与接受增强标准治疗的BMSM相比，接受PrEP移动的的BMSM 消息传递干预将显示更多的出席PrEP服务预约和降低艾滋病毒风险 4周和16周时的行为。 增加信息， 黑人男男性接触者在UMMC动机和行为技能 性病/艾滋病毒检测诊所，负责启动PrEP护理 PrEP的候选人，但不 启动PrEP，收到8-16条文本减少结构性障碍 在4周内传播减少艾滋病毒/性传播感染风险行为的信息 与PrEP和HIV建立联系 预防内容。参加PrEP服务 任命