PRIDE: Functional and Translational Genomics of Blood Disorders

PRIDE：血液疾病的功能和转化基因组学

• 批准号: 9292356
• 负责人: Betty Sue Pace
• 金额: $ 34.32万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2019-01-27
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9292356
• 关键词: Address; African American; Applications Grants; Award; Behavioral Sciences; Biomedical Research; Collaborations; Complement; Continuing Education; Development; Doctor of Philosophy; Educational Curriculum; Educational workshop; Elements; Ethnic Origin; Evaluation; Extramural Activities; Face; Faculty; Feedback; Fostering; Funding; Funding Mechanisms; Genomic medicine; Genomics; Goals; Grant; Health; Healthcare; Heart Diseases; Hematological Disease; Individual; Institution; Laboratories; Leadership; Learning; Lung diseases; Measures; Medical; Mentors; Mentorship; National Heart, Lung, and Blood Institute; Outcome; Paint; Private Sector; Program Evaluation; Public Sector; Race; Recruitment Activity; Reporting; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Training; Resources; Scientist; Sleep Disorders; Social support; Stimulus; Testing; Texas; Training; Training Programs; Training Technics; Underrepresented Minority; United States National Institutes of Health; Universities; Visit; Writing; base; career; design; didactic education; experience; functional genomics; improved; innovation; interest; investigator training; knowledge base; member; multidisciplinary; peer coaching; peer networks; professor; programs; research and development; skills; skills training; statistics; success; summer institute; translational genomics; translational medicine; virtual

 DESCRIPTION (provided by applicant): One of the most important challenges we face in healthcare today is a lack of diversity in the US biomedical research workforce. To address this issue, in 2006 the National Heart Lung and Blood Institute (NHLBI) funded a Summer Institute Program to Increase Diversity (SIPID) training program, and later the Program to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE). We were founding members of both innovative programs, with the Functional and Applied Genomics of Blood Disorders Summer Institute currently in its last year at Georgia Regents University (GRU). We recruited and trained 47 junior faculty mentees who received intense mentoring, including hands-on training in bench research and grantsmanship. Program evaluations suggest these Summer Institutes have achieved their primary goal of aiding mentees in obtaining extramural grant funding within two years of program completion. The renewed GRU-PRIDE program will keep all of the successful elements of the previous program, while offering several innovative changes to the curriculum and mentoring activities. The goal of our program during this renewal will be to empower 36 mentees to develop a competitive research project through an intensive mentoring and hands-on bench research training experience; success of this program will be measured, in part, by the ability of each mentee to acquire extramural funding within two years following program completion. To reach this goal we propose the following aims: AIM 1 Conduct GRU PRIDE 1 Summer Institute: implementation of the GRU PRIDE 1 Summer Institute, including the establishment of individual Mentorship Committees in collaboration with the Coordination Core will begin during the first year of this award. The Summer Institute is composed of a multidisciplinary didactic curriculum, hands-on bench research training and a grant-writing workshop to expand the knowledge base of mentees in the field of genomics research as it applies to blood disorders. AIM 2 Mentoring and Networking Activity: In addition to the continuation of our Mentorship Committees, we will implement two innovations: a mentee virtual network and a peer- networking laboratory. Mentees will make a mid-year visit to the mentor's institution to refine their research project, grant-writing skills, career planning, and bench training techniques. AIM 3 Conduct PRIDE 2 Summer Institute: Mentees will participate in the PRIDE 2 Summer Institute to provide additional functional and translational genomics research training and to improve their grant-writing skills. Each mentee will be required to submit a grant application to acquire NHLBI-sponsored or other extramural funding. The GRU-PRIDE program curriculum and mentee success will be evaluated continuously in collaboration with the national Coordination Core.

 描述（由申请人提供）：我们当今在医疗保健领域面临的最重要挑战之一是美国生物医学研究人员缺乏多样性。为了解决这个问题，国家心肺和血液研究所 (NHLBI) 于 2006 年资助了一项增加多样性夏季研究所计划 (SIPID) 培训计划，以及后来的增加从事健康相关研究的个人多样性计划 (PRIDE)。我们是这两个创新项目的创始成员，其中血液疾病功能和应用基因组学夏季研究所目前已进入佐治亚摄政大学 (GRU) 的最后一年。我们招募并培训了 47 名初级教员，他们接受了严格的指导，包括实验室研究和资助方面的实践培训。项目评估表明，这些暑期学院已经实现了帮助学员在项目完成后两年内获得校外资助的主要目标。新的 GRU-PRIDE 计划将保留之前计划的所有成功要素，同时对课程和指导活动进行一些创新性的改变。本次更新期间我们计划的目标是让 36 名受训者能够通过强化指导和实践台架研究培训经验来开发具有竞争力的研究项目；该方案是否成功，部分取决于每个学员在方案完成后两年内获得校外资金的能力。为了实现这一目标，我们提出以下目标： AIM 1 开展 GRU PRIDE 1 夏季学院：实施 GRU PRIDE 1 夏季学院，包括与协调核心合作建立个人指导委员会，将在该奖项的第一年开始。暑期学院由多学科教学课程、实践台研究培训和资助写作研讨会组成，旨在扩大学员在基因组学研究领域的知识基础，因为它适用于血液疾病。 AIM 2 指导和网络活动：除了继续保留我们的指导委员会外，我们还将实施两项创新：受训者虚拟网络和同行网络实验室。受训者将在年中访问导师的机构，以完善他们的研究项目、资助写作技巧、职业规划和替补培训技巧。 AIM 3 开展 PRIDE 2 夏季学​​院：学员将参加 PRIDE 2 夏季学​​院，提供额外的功能和转化基因组学研究培训，并提高他们的资助写作技能。每个受训者都需要提交拨款申请以获得 NHLBI 赞助的资金或其他外部资金。 GRU-PRIDE 计划课程和学员的成功将与国家协调核心合作不断进行评估。