Sickle Cell Disease Research Center (SCDRC) Summer Institute/Mentoring Program

镰状细胞病研究中心 (SCDRC) 暑期学院/指导计划

• 批准号: 7768334
• 负责人: Betty Sue Pace
• 金额: $ 7.3万
• 依托单位: UNIVERSITY OF TEXAS DALLAS
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2010-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7768334
• 关键词: Address; African American; American Indians; Americas; Area; Award; Basic Science; Behavioral Sciences; Biology; Biomedical Research; Blood; Cell membrane; Chemistry; Client satisfaction; Clinical Research; Collaborations; Communication; Continuing Education; Development; Doctor of Philosophy; Educational Curriculum; Ensure; Environment; Equilibrium; Ethics; Ethnic group; Extramural Activities; Faculty; Fellowship; Fostering; Foundations; Funding; Funding Opportunities; Future; Gene Expression; Gene Expression Regulation; Genomics; Globin; Goals; Grant; Gray unit of radiation dose; Hand; Heart; Hematological Disease; Hispanics; Individual; Institutes; Joints; Knowledge; Laboratories; Life; Lung; Mentors; Minority; Minority Groups; Mission; Morbidity - disease rate; National Heart, Lung, and Blood Institute; National Human Genome Research Institute; Outcome; Participant; Patients; Physicians; Proteins; Proteomics; Public Health; Public Sector; Recruitment Activity; Reporting; Research; Research Personnel; Research Priority; Research Project Grants; Research Training; Resources; Schools; Science; Scientific Societies; Scientist; Severity of illness; Sickle Cell; Sickle Cell Anemia; Sleep Disorders; Stress; Structure; Students; Surface; Texas; Training; Training Programs; Underrepresented Minority; Universities; Visit; Work; Writing; abstracting; analytical tool; base; career; career development; college; genome-wide; health disparity; improved; innovation; interdisciplinary approach; interest; lectures; meetings; member; mortality; multidisciplinary; physical science; programs; racial and ethnic; skills; success; teacher

DESCRIPTION (provided by applicant): The mission of the Sickle Cell Disease Research Center (SCDRC) is to "actively and aggressively participate in the substantive development of basic research and training efforts to improve treatment options or cure sickle cell disease". The SIPID funding initiative is relevant to the mission of the SCDRC project because it will utilize a multidisciplinary approach to increase underrepresented minorities in Biomedical Research related to heart, lung, and blood disease. The program will fund summer institutes to enable 10-12 participants from underrepresented racial and ethnic groups to further develop their research skills and knowledge, thereby enhancing their career development as faculty members or scientists. The summer institute will focus on genomic-based biomedical research related to sickle cell disease (SCD): to introduce multidisciplinary approaches to genomic research and establish a broad base working knowledge of current technological advances and identify potential areas of future research projects involving modern DMA and protein analytical tools. This will be accomplished through classroom didactic lectures and hands-on bench training in laboratory settings. Our goals will include: increasing the number of racial and ethical underserved individuals who enter research careers by establishing a structured mentored training program and long-term research collaborations between mentors and mentees; increasing grantsmanship skills of participants; and identifying extramural research funding opportunities. Diversity of scientific and scholarly activity will be valuable in improving the public health of patients and subjects from diverse backgrounds. Studies have suggested that a racially concordant scientific staff is more successful in recruiting individuals from minority groups into clinical studies. Racially similar physician-patient dyads have been shown to be related to greater patient satisfaction in ways that may also enhance communication and participation in a clinical research setting. The need for a diverse workforce permeates all aspects of the nation's public health-related research efforts. Because minorities suffer a disproportionate burden of morbidity and mortality associated with HLBS disorders, there is a critical need to increase the number of investigators conducting research on health disparities in HLBS disorders, such as sickle cell disease. (End of Abstract)

描述（由申请人提供）： 镰状细胞病研究中心（SCDRC）的使命是“积极主动地参与基础研究和培训工作的实质性发展，以改善治疗方案或治愈镰状细胞病”。SIPID资助倡议与SCDRC项目的使命相关，因为它将利用多学科方法来增加与心脏、肺和血液疾病相关的生物医学研究中代表性不足的少数民族。该计划将资助暑期学院，使10-12名来自代表性不足的种族和族裔群体的参与者能够进一步发展他们的研究技能和知识，从而提高他们作为教师或科学家的职业发展。夏季研究所将专注于与镰状细胞病（SCD）相关的基于基因组的生物医学研究：将多学科方法引入基因组研究，并建立当前技术进步的广泛基础工作知识，并确定涉及现代DMA和蛋白质分析工具的未来研究项目的潜在领域。这将通过课堂教学讲座和实验室环境中的动手实验台培训来实现。我们的目标包括：通过建立一个结构化的指导培训计划和导师与被指导者之间的长期研究合作，增加进入研究职业的种族和道德服务不足的个人的数量;提高参与者的研究技能;并确定校外研究资助机会。科学和学术活动的多样性将有助于改善来自不同背景的患者和受试者的公共健康。研究表明，种族一致的科学工作人员在招募少数群体的个人进入临床研究方面更成功。种族相似的医生-患者二人组已被证明与更高的患者满意度有关，其方式也可能增强临床研究环境中的沟通和参与。对多样化劳动力的需求渗透到国家公共卫生相关研究工作的各个方面。由于少数民族遭受的发病率和死亡率与HLBS疾病相关的不成比例的负担，有一个迫切需要增加的数量进行研究的HLBS疾病，如镰状细胞病的健康差异的调查。 (End摘要）