PRIDE-Functional and Applied Genomics of Blood Disorders

PRIDE-血液疾病的功能和应用基因组学

• 批准号: 8219409
• 负责人: Betty Sue Pace
• 金额: $ 30万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8219409
• 关键词: PRIDE; Functional; Applied; Genomics; Blood

DESCRIPTION (provided by applicant): Project Summary/Abstract: Reports from the private and public sectors provide strong evidence that diversity remains an important challenge in biomedical and behavioral science research programs. To address these issues a Summer Institute Program to Increase Diversity (SIPID)-Functional Genomics of Blood Disorders was funded in 2006 by the National Heart Lung Blood Institute (NHLBI) at the University of Texas at Dallas. We recruited 25 junior faculty mentees who were assigned mentors from a pool of leading investigators in their area of research focus. We taught mentees diverse topics and hands-on bench research and grantsmanship skills. Program evaluations suggest the SIPID program will achieve its primary goal of aiding mentees in obtaining independent grant funding within two years of program completion. We propose to continue this mentored training program to improve the recruitment and retention of underrepresented and disabled faculty in health-related careers. We will establish a Program to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE)-Functional and Applied Genomics of Blood Disorders to complete the following aims. Aim 1 (PRIDE 1): In collaboration with the Coordination Core, Mentorship Committees will be established and long-term partnerships developed based on the research interests of mentees and expertise of mentors. A multidisciplinary didactic curriculum related to functional and applied genomics research, grant writing skills and hands-on-bench research techniques will be designed to increase the knowledge and skills of mentees. Aim 2 (Mentoring and Networking Activity): The continued development of the mentor- mentee relationship will be fostered by regular contact with the Mentoring Committee throughout the year. A mid-year visit to the mentor's institution will be sponsored to refine the mentee's research project, grant writing skills, career planning, and additional bench training techniques. Aim 3 (PRIDE 2): PRIDE mentees will continue to develop grantsmanship skills and refine their research projects in order to submit a grant application to acquire NHLBI-sponsored funding. The need for a diverse workforce permeates all aspects of the nation's public health-related research efforts. The PRIDE initiative will fund summer institutes to enable junior faculty to further develop their research skills and knowledge in order to increase the number of underrepresented and disabled scientists in biomedical research careers. Because underrepresented individuals suffer a disproportionate burden of morbidity and mortality associated with heart, lung, blood, and sleep disorders, there is a critical need to increase the number of investigators conducting research on health disparities in this area. PUBLIC HEALTH RELEVANCE: Project Narrative: Currently there exists a growing disparity in the number of minority scientists engaged in biomedical research. Mentoring and training are essential to the retention and recruitment of underrepresented and disabled faculty. The PRIDE-Functional and Applied Genomics of Blood Disorders Summer Institute at the University of Texas at Dallas (UTD) will address these challenges by establishing mentor-mentee partnerships based on common research interests. In addition, the program will provide the mentees with research experiences in functional and applied genomics, develop grantsmanship skills, develop specific research projects, and improve their long-term fundability. The UTD-PRIDE program will strategically complement the efforts of the National Heart Lung and Blood Institute to promote and diversify the country's biomedical workforce.

描述(由申请人提供)：项目摘要/摘要：来自私营和公共部门的报告提供了强有力的证据，表明多样性仍然是生物医学和行为科学研究项目中的一个重要挑战。为了解决这些问题，2006年由德克萨斯大学达拉斯分校的国家心肺血液研究所(NHLBI)资助了一项增加多样性夏季研究所计划(SIPID)-血液疾病功能基因组学。我们招募了25名初级教师导师，他们从他们的研究重点领域的一批领先研究人员中分配了导师。我们教授学员不同的主题、实际操作的板凳研究和授勋技巧。计划评估表明，SIPID计划将实现其主要目标，即在计划完成后两年内帮助受训者获得独立赠款资金。我们建议继续这一有指导的培训计划，以改善在与健康相关的职业中招聘和留住代表性不足和残疾教师的情况。我们将建立一个增加多样性的计划 在从事健康相关研究(PROID)-血液疾病功能和应用基因组学的个人中，以完成以下目标。目标1(PARE 1)：将与协调核心协作，建立导师委员会，并根据学员的研究兴趣和导师的专门知识发展长期伙伴关系。将设计一个与功能和应用基因组学研究、赠款撰写技能和实际操作研究技术有关的多学科教学课程，以增加学员的知识和技能。目标2(辅导和联网活动)：将通过全年与辅导委员会的定期接触来促进导师与学员关系的持续发展。年中访问导师的机构将得到赞助，以完善导师的研究项目，资助写作技能，职业规划，以及额外的板凳培训技术。目标3(Pride 2)：Pride学员将继续发展资助者技能，完善他们的研究项目，以便提交赠款申请，以获得NHLBI赞助的资金。对多样化劳动力的需求渗透到国家公共卫生相关研究工作的方方面面。Pride计划将资助暑期学院，使初级教师能够进一步发展他们的研究技能和知识，以增加生物医学研究生涯中代表不足和残疾的科学家的数量。由于代表性不足的人承受着与心肺、血液和睡眠障碍相关的不成比例的发病率和死亡率负担，因此迫切需要增加研究这一领域健康差距的研究人员的数量。 公共卫生相关性：项目叙述：目前，从事生物医学研究的少数族裔科学家的数量存在着越来越大的差距。辅导和培训对于留住和招聘任职人数不足和残疾的教职员工至关重要。得克萨斯大学达拉斯分校(UTD)的血液疾病骄傲功能和应用基因组学夏季研究所将通过建立基于共同研究兴趣的导师-学员伙伴关系来应对这些挑战。此外，该计划将为受训者提供功能和应用基因组学方面的研究经验，培养技能，开发具体的研究项目，并提高他们的长期资助能力。UTD-PROID计划将从战略上补充国家心肺和血液研究所促进和多样化国家生物医学劳动力的努力。