PRIDE-Functional and Applied Genomics of Blood Disorders

PRIDE-血液疾病的功能和应用基因组学

• 批准号: 8219409
• 负责人: Betty Sue Pace
• 金额: $ 30万
• 依托单位: AUGUSTA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-09-20 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8219409
• 关键词: PRIDE; Functional; Applied; Genomics; Blood

DESCRIPTION (provided by applicant): Project Summary/Abstract: Reports from the private and public sectors provide strong evidence that diversity remains an important challenge in biomedical and behavioral science research programs. To address these issues a Summer Institute Program to Increase Diversity (SIPID)-Functional Genomics of Blood Disorders was funded in 2006 by the National Heart Lung Blood Institute (NHLBI) at the University of Texas at Dallas. We recruited 25 junior faculty mentees who were assigned mentors from a pool of leading investigators in their area of research focus. We taught mentees diverse topics and hands-on bench research and grantsmanship skills. Program evaluations suggest the SIPID program will achieve its primary goal of aiding mentees in obtaining independent grant funding within two years of program completion. We propose to continue this mentored training program to improve the recruitment and retention of underrepresented and disabled faculty in health-related careers. We will establish a Program to Increase Diversity Among Individuals Engaged in Health-Related Research (PRIDE)-Functional and Applied Genomics of Blood Disorders to complete the following aims. Aim 1 (PRIDE 1): In collaboration with the Coordination Core, Mentorship Committees will be established and long-term partnerships developed based on the research interests of mentees and expertise of mentors. A multidisciplinary didactic curriculum related to functional and applied genomics research, grant writing skills and hands-on-bench research techniques will be designed to increase the knowledge and skills of mentees. Aim 2 (Mentoring and Networking Activity): The continued development of the mentor- mentee relationship will be fostered by regular contact with the Mentoring Committee throughout the year. A mid-year visit to the mentor's institution will be sponsored to refine the mentee's research project, grant writing skills, career planning, and additional bench training techniques. Aim 3 (PRIDE 2): PRIDE mentees will continue to develop grantsmanship skills and refine their research projects in order to submit a grant application to acquire NHLBI-sponsored funding. The need for a diverse workforce permeates all aspects of the nation's public health-related research efforts. The PRIDE initiative will fund summer institutes to enable junior faculty to further develop their research skills and knowledge in order to increase the number of underrepresented and disabled scientists in biomedical research careers. Because underrepresented individuals suffer a disproportionate burden of morbidity and mortality associated with heart, lung, blood, and sleep disorders, there is a critical need to increase the number of investigators conducting research on health disparities in this area. PUBLIC HEALTH RELEVANCE: Project Narrative: Currently there exists a growing disparity in the number of minority scientists engaged in biomedical research. Mentoring and training are essential to the retention and recruitment of underrepresented and disabled faculty. The PRIDE-Functional and Applied Genomics of Blood Disorders Summer Institute at the University of Texas at Dallas (UTD) will address these challenges by establishing mentor-mentee partnerships based on common research interests. In addition, the program will provide the mentees with research experiences in functional and applied genomics, develop grantsmanship skills, develop specific research projects, and improve their long-term fundability. The UTD-PRIDE program will strategically complement the efforts of the National Heart Lung and Blood Institute to promote and diversify the country's biomedical workforce.

项目摘要/摘要：来自私营和公共部门的报告提供了强有力的证据，表明多样性仍然是生物医学和行为科学研究项目的一个重要挑战。为了解决这些问题，德克萨斯大学达拉斯分校的国家心肺血液研究所（NHLBI）于2006年资助了一项增加多样性(SIPID)-血液疾病功能基因组学的暑期研究所计划。我们招募了25名初级教师学员，他们从各自研究领域的顶尖研究人员中被分配为导师。我们教学员不同的主题和动手实验研究和资助技巧。项目评估表明，SIPID项目将实现其主要目标，即在两年内帮助学员获得独立的资助资金。我们建议继续这项指导培训计划，以改善与健康相关职业中代表性不足和残疾教师的招聘和保留。我们将建立一个增加多样性的计划