Low-Cost Portable Inhalation Therapy Platform for Needle-Free DNA-Based Influenza Vaccination

用于无针 DNA 流感疫苗接种的低成本便携式吸入治疗平台

• 批准号: nhmrc : GNT1112870
• 负责人: A/Pr Aeron Hurt
• 金额: $ 52.46万
• 依托单位: RMIT University
• 依托单位国家: 澳大利亚
• 项目类别: Development Grants
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/low-cost-portable-influenza-vaccination/1346825
• 关键词: Low; Cost; Portable; Inhalation; Therapy

Influenza affects a large proportion of the global population and can result in many deaths in a pandemic. A DNA influenza vaccine overcomes the possibility of severe side effects associated with commonly used vaccines based on weakened viruses and can be rapidly produced and easily transported without refrigeration. DNA vaccines are however unstable and difficult to deliver. We propose to address this with a low-cost and portable handheld device which allows the vaccine to simply be inhaled.

流感影响全球大部分人口，在大流行中可导致许多人死亡。DNA流感疫苗克服了与基于减毒病毒的常用疫苗相关的严重副作用的可能性，并且可以快速生产和容易运输而无需冷藏。然而，DNA疫苗不稳定且难以递送。我们建议用一种低成本的便携式手持设备来解决这个问题，这种设备可以让疫苗简单地吸入。