Acupressure Intervention to Improve Fatigue and Physical Functioning of Chinese Immigrant Breast Cancer Survivors

穴位按摩干预改善中国移民乳腺癌幸存者的疲劳和身体机能

• 批准号: 9178314
• 负责人: Judy Huei-yu Wang
• 金额: $ 21.95万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2018-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9178314
• 关键词: 21 year old; Acupressure; Acupuncture Points; Address; Adverse effects; Affect; Aftercare; Anxiety; Asian Americans; Biological; Breast Cancer Patient; Breast Cancer survivor; Cancer Patient; Cancer Survivor; Cancer Survivorship; Caucasians; Chinese American; Chinese People; Chinese Traditional Medicine; Clinical; Communities; Control Groups; Data; Diagnosis; Distal; Enrollment; Exercise; Family; Fatigue; Generations; Goals; Home environment; Immigrant; Incidence; Information Systems; Intervention; Intervention Studies; Knowledge; Language; Learning; Life; Limited English Proficiency; Linguistics; Los Angeles; Malignant Neoplasms; Malignant neoplasm of lung; Measurement; Mental Depression; Methods; Minority; Neighborhoods; Not Hispanic or Latino; Occupations; Organ; Outcome; Participant; Patient Outcomes Assessments; Patients; Performance at work; Physical Function; Play; Population; Process; Productivity; Psyche structure; Qi; Quality of Care; Quality of life; Randomized; Randomized Controlled Trials; Reporting; Research; Resources; Security; Self-Administered; Side; Sleep; Sleep disturbances; Staging; Stress; Subgroup; Survivors; Symptoms; Telephone Interviews; Testing; Time; Toxic effect; Treatment Efficacy; United States; Woman; Work; base; cancer health disparity; cancer type; common symptom; cost; cost effectiveness; design; efficacy testing; experience; follow-up; functional status; improved; innovation; malignant breast neoplasm; meetings; neoplasm registry; neurochemistry; neurotransmitter release; post intervention; pressure; randomized trial; socioeconomics; sound; therapy design; treatment as usual; treatment strategy

ABSTRACT Minority and immigrant cancer patients are more likely to have poorer physical functioning than Non-Hispanic White patients. Cancer-related fatigue (CRF) is one of the most common symptoms associated with declines in physical functioning. Chinese Americans are the largest subgroup of Asian Americans and the fastest growing immigrant group in the US. Our data suggests that Chinese immigrant breast cancer survivors have poorer physical functioning than NHW survivors; in part because the former are more likely to experience CRF than the latter. Chinese immigrants have fewer socioeconomic resources and experience cultural and linguistic challenges when attempting to access quality care, making their adjustment to cancer even harder. Despite these documented disparities, there are no interventions designed to improve Chinese immigrant survivors’ CRF or physical functioning. Self-administered acupressure, a low-cost and low-toxicity approach originating from Traditional Chinese Medicine, is emerging to help cancer patients reduce CRF and boost energy to meet daily demands at work and home. Therefore, we propose a randomized controlled trial (RCT) to develop and pilot test the efficacy of a home-based, self-administered acupressure intervention in improving CRF (proximal outcome), physical functioning and other quality of life outcomes (distal outcomes) of Chinese immigrant breast cancer survivors (versus usual care control group). We will use the patient-reported outcomes measurement information system (PROMIS®) short forms to assess our outcome variables. Using Los Angeles (LA) cancer registry cases, we will enroll 124 first-generation, Chinese-speaking immigrant women with moderate to severe levels of fatigue, diagnosed with stage 0-III breast cancer, aged 21-69, and 1-5 years post-primary treatment. Based on an adaptive treatment strategy design, participants will be randomized to either the self-acupressure intervention or control groups. The self-acupressure group will learn how to press three chief energy acupoints on each side of the body through a 10-minute Chinese-language video (DVD) and practice self-acupressure every day (one minute per acupoint; a total of 6 minutes per day) for a six-week intervention period. Participants will be telephone interviewed twice: at baseline and 6-weeks post-intervention. The research examining CRF and functional status of Chinese immigrant cancer survivors is lacking, and the impact of self- acupressure on cancer survivorship has not been sufficiently tested. PROMIS® is also underused in immigrant populations. Our proposed intervention study is the first of its kind that we are aware of. Knowledge gained from this study will be significant and innovative in advancing the measurement and intervention approaches of cancer survivorship and directing scientifically sound efforts to reduce cancer disparities experienced by the growing yet underserved Chinese immigrant population.

摘要