An Integrative Approach to Control Group Creation for Prevention Research

预防研究控制组创建的综合方法

基本信息

  • 批准号:
    9754730
  • 负责人:
  • 金额:
    $ 48.66万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2016
  • 资助国家:
    美国
  • 起止时间:
    2016-08-01 至 2021-05-31
  • 项目状态:
    已结题

项目摘要

PROJECT ABSTRACT The goal of this Phase II SBIR project is to develop a method for creating algorithmically generated control groups – virtual controls. These will be composed of synthetic cases that have two characteristics: (1) pretest similarity to whatever prevention treatment group may present itself and (2) patterns of change over time that closely mimic the normal course of alcohol and drug use development. The field of alcohol and drug prevention is one that has significantly matured and has rich data resources that can be employed to this end. Notably, numerous school and community efficacy studies have employed control groups in randomized control trials. Additional etiological and epidemiological studies have collected similar data. Given the large amount of data available for analysis, it is now possible to model the onset of alcohol and drug use among adolescents. We propose to gather data from previous studies and develop statistical models that can be used to predict the onset of alcohol and drug use. An algorithm will be developed that will create integrative control cases to match to a treatment group’s demographics and pretest mediating variable scores and then estimate future drug use. Several benefits of this method are anticipated. Alcohol and drug prevention researchers and practitioners will be able to use this approach to test the effectiveness of disseminated interventions and to quickly evaluate the potential of new and alternative prevention interventions. Specifically, this method will provide a means to evaluate the effectiveness of alcohol and drug prevention programs that are disseminated when randomization cannot occur. This method will also make evaluating new and adapted programs easier by reducing the challenges of recruitment, subject retention, and onsite data collection and pretest non-equivalence that often occur when l classrooms, schools and communities are assigned to condition. In this project, we will (1) gather data from previous longitudinal drug and alcohol research projects focused on adolescents; (2) harmonize these data to match a predefined coding scheme and include them in an integrated referential database; (3) refine and validate statistical models developed during Phase I to ensure algorithms used to generate virtual control cases are valid and replicable; (4) prepare a web-based system that will allow virtual control group technology to be maximally automated; and (5) conduct de novo field trials of disseminated interventions to demonstrate the viability of the system for providing meaningful comparisons.
项目摘要

项目成果

期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
An Algorithm for Creating Virtual Controls Using Integrated and Harmonized Longitudinal Data.
  • DOI:
    10.1177/0163278718772882
  • 发表时间:
    2018-06
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Hansen WB;Chen SH;Saldana S;Ip EH
  • 通讯作者:
    Ip EH
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William B. Hansen其他文献

Behavioral predictors of abstinence: early indicators of a dependence on tobacco among adolescents.
戒烟行为预测因素:青少年对烟草依赖的早期指标。
Prevention of alcohol use and abuse.
预防饮酒和滥用酒精。
  • DOI:
  • 发表时间:
    1994
  • 期刊:
  • 影响因子:
    5.1
  • 作者:
    William B. Hansen
  • 通讯作者:
    William B. Hansen
Ciencia, política y práctica: lecciones desde Estados Unidos de América
科学、政治和实践:美洲大学的学习
  • DOI:
  • 发表时间:
    2007
  • 期刊:
  • 影响因子:
    0
  • 作者:
    William B. Hansen;Linda Dusenbury
  • 通讯作者:
    Linda Dusenbury

William B. Hansen的其他文献

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{{ truncateString('William B. Hansen', 18)}}的其他基金

Prototype for an online skills-based drug prevention program targeting youth 11-13
针对 11-13 岁青少年的基于技能的在线毒品预防计划原型
  • 批准号:
    10382037
  • 财政年份:
    2021
  • 资助金额:
    $ 48.66万
  • 项目类别:
An Integrative Approach to Control Group Creation for Prevention Research
预防研究控制组创建的综合方法
  • 批准号:
    9045107
  • 财政年份:
    2016
  • 资助金额:
    $ 48.66万
  • 项目类别:
Pediatrician Office Drug Prevention
儿科医生办公室药物预防
  • 批准号:
    8591737
  • 财政年份:
    2013
  • 资助金额:
    $ 48.66万
  • 项目类别:
Feasibility of a Social Network Preventive Intervention
社交网络预防干预的可行性
  • 批准号:
    8436203
  • 财政年份:
    2012
  • 资助金额:
    $ 48.66万
  • 项目类别:
Feasibility of a Social Network Preventive Intervention
社交网络预防干预的可行性
  • 批准号:
    8229886
  • 财政年份:
    2012
  • 资助金额:
    $ 48.66万
  • 项目类别:
Evaluation-Based Effectiveness Testing
基于评估的有效性测试
  • 批准号:
    8123884
  • 财政年份:
    2011
  • 资助金额:
    $ 48.66万
  • 项目类别:
Evaluation-Based Effectiveness Testing
基于评估的有效性测试
  • 批准号:
    8248162
  • 财政年份:
    2011
  • 资助金额:
    $ 48.66万
  • 项目类别:
The Impact of Adaptation on Successful Implementation
适应对成功实施的影响
  • 批准号:
    7894850
  • 财政年份:
    2009
  • 资助金额:
    $ 48.66万
  • 项目类别:
The Impact of Adaptation on Successful Implementation
适应对成功实施的影响
  • 批准号:
    7433474
  • 财政年份:
    2009
  • 资助金额:
    $ 48.66万
  • 项目类别:
Evaluation-Based Effectiveness Testing
基于评估的有效性测试
  • 批准号:
    7394619
  • 财政年份:
    2008
  • 资助金额:
    $ 48.66万
  • 项目类别:

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