Pollutant Responses in Marine Organisms (PRIMO 20)

海洋生物中的污染物反应 (PRIMO 20)

• 批准号: 9760885
• 负责人: Richard Di Giulio
• 金额: $ 1.5万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-03-15 至 2020-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9760885
• 关键词: Address; Area; Biological Markers; Boston; Chemicals; Comparative Biology; Development; Disease; Endocrine disruption; Environment; Exposure to; Fees; Fostering; Fresh Water; Funding; Government; Graduate Education; Health; Human; Individual; Interdisciplinary Study; Letters; Location; Marines; Metals; Molecular; National Institute of Environmental Health Sciences; North Carolina; Oceans; Organism; Participant; Pesticides; Play; Research; Research Personnel; Science; Scientific Societies; Scientist; Students; Superfund; Time; Toxic effect; Translational Research; Travel; Universities; Washington; Wood material; Xenobiotic Metabolism; aquatic organism; cost; falls; genotoxicity; graduate student; human model; marine organism; meetings; nanomaterials; pollutant; programs; receptor-mediated signaling; response; stressor; symposium

This will be the Pollutant Responses in Marine Organisms (PRIMO 20) 20th annual conference which meets every other year at various locations world-wide. PRIMO 20 will be the first meeting in the U.S. since 2011, held in Long Beach, CA. This very prestigious meeting brings together top scientists and their students from around the world who investigate the impacts of chemical pollutants on marine and freshwater organisms. A major thrust historically and currently is the elucidation of underlying molecular mechanisms of toxicity. This thrust extends the relevance of the meeting from impacts in marine/aquatic environments to human health, and thus to NIEHS. PRIMO has also had particular relevance to the Superfund Research Program (SRP). The symposium will include sessions addressing mechanisms and impacts of POPs, metals, pesticides, nanomaterials, microplastics and other ubiquitous pollutants, many of which fall under the purview of the SRP. Additionally, the science emphasized includes endocrine disruption, xenobiotic metabolism, `omic approaches, genotoxicity, effects on development and transgenerational impacts, receptor-mediated signaling, and biomarkers of exposure and effect. Many Superfund Program investigators have been and continue to be highly involved in PRIMO meetings. One of PRIMO's co-founders is Dr. John Stegeman, a long-time investigator with the Boston University Superfund Research Center (see letter of support). Other SRP investigators that are regular participants in PRIMO meetings include Evan Gallagher (University of Washington), Mark Hahn (Woods Hole/Boston University), Dan Schlenk (UC Riverside), Seth Kullman (North Carolina State University), and David Hinton and Richard Di Giulio (Duke University). Several of these individuals are playing key roles in the planning for PRIMO 20. PRIMO is not affiliated with any scientific society. The meetings are funded by registration fees and modest support from a few relevant companies, government (SRP via the R13 mechanism has provided support for past meetings in the U.S.), and universities. Support beyond registration fees is used to support travel costs for graduate students.

这将是海洋生物的污染物反应（PRIMO 20）第20届年会 每隔一年在世界各地举行会议。PRIMO 20将是第一个 自2011年以来，在美国加州长滩举行的会议。这个非常有声望的会议带来了 来自世界各地的顶尖科学家和他们的学生一起调查 化学污染物对海洋和淡水生物的影响。历史上的一个主要推力， 目前正在阐明毒性的潜在分子机制。这种推力延伸到 会议与海洋/水生环境影响对人类健康的相关性，以及 对于NIEHS。 PRIMO还与超级基金研究方案（SRP）特别相关。的 专题讨论会将包括讨论持久性有机污染物、金属 农药、纳米材料、微塑料和其他无处不在的污染物，其中许多都属于 在SRP的权限范围内。此外，强调的科学包括内分泌 破坏、异生物质代谢、“组学方法”、遗传毒性、对发育的影响， 跨代影响、受体介导的信号传导以及暴露和效应的生物标志物。 许多超级基金项目调查人员一直并将继续高度参与PRIMO 会议. PRIMO的联合创始人之一是John Stegeman博士，他是一位长期的研究人员。 波士顿大学超级基金研究中心（见支持信）。其他SRP研究者 定期参加PRIMO会议的有埃文·加拉格尔（牛津大学）， 华盛顿）、马克·哈恩（伍兹霍尔/波士顿大学）、丹·施伦克（加州大学滨江分校）、赛斯 库尔曼（北卡罗来纳州州立大学），以及大卫欣顿和理查德迪朱利奥（杜克 大学）。其中几个人在PRIMO 20的规划中发挥了关键作用。 PRIMO不隶属于任何科学协会。会议的经费来自登记费 以及来自一些相关公司、政府（通过R13机制的SRP）的适度支持 为过去在美国举行的会议提供了支持），和大学。年之后的支持 注册费用于支付研究生的旅费。