Duke University Program in Environmental Health

杜克大学环境健康项目

• 批准号: 10664920
• 负责人: Richard Di Giulio
• 金额: $ 31.94万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10664920
• 关键词: Environmental Health; Universities; programs

ABSTRACT The Duke University Program in Environmental Health (UPEH) is a pre-doctoral training program that rigorously prepares students for the complexity of research careers in environmental health. The UPEH is an interdepartmental, transdisciplinary program in which PhD degrees are awarded jointly by a Department within Duke University and the UPEH. Fellows receive high-quality training including: (1) classroom instruction for content mastery in core topical areas (Environmental Health, Toxicology, Exposure Science, Epidemiology, etc), and quantitative methods used in cutting-edge research (Biostatistics, Exposure Science Modelling, Big Data Analytics, etc); (2) seminars and symposia that include literature analysis and presentation of primary research; (3) instruction in Responsible Conduct of Research; (4) laboratory research; and (5) professional development, including communication and matrix management of scientific teams. Research strengths include: (1) human environmental health with specific strengths in cardiopulmonary health and disease, developmental and children’s health, neurological health, cancer and the environment, and global health; (2) Exposure science with a focus on endocrine disrupters, pharmaceuticals, flame retardants, other organic pollutants including hydrocarbons, nanomaterials and inorganic pollutants including metals and metalloids, and (3) Environmental toxicology, focused on molecular mechanisms of action that affect health. UPEH programming is supported by the outstanding research environment of Duke's Medical Center, the Nicholas School of the Environment, the Pratt School of Engineering, the Global Health Institute, and Trinity College of Arts and Sciences, and provides a uniquely integrated educational environment with access to shared facilities, support cores, and resources to support the fellows training in cutting-edge research. Core Duke faculty members in the UPEH serve as primary advisors for pre-doctoral students. The Program is further enriched by adjunct faculty and external advisors from our neighboring Research Triangle Park-based institutions such as the NIEHS, US EPA, and RTI, in addition to our sister triangle universities (North Carolina Central University, NC State University, and UNC Chapel Hill). These faculty members provide seminars, lectures, serve on student committees, and provide technical expertise, research facilities and career guidance. Our recruiting and admissions efforts have consistently provided us with outstanding trainees who are eager to embark upon careers in environmental health and related sub-disciplines, with a particular emphasis on recruiting and retaining underrepresented minorities. The success of our students post- graduation is a reflection of the quality of the students, faculty, and broader environment of the UPEH.

摘要 杜克大学环境健康项目（UPEH）是一个博士前培训项目， 严格准备学生在环境健康研究事业的复杂性。UPEH是一个 跨部门，跨学科的计划，其中博士学位由一个部门内联合授予 杜克大学和UPEH。研究员接受高质量的培训，包括：（1） 掌握核心主题领域的内容（环境健康，毒理学，暴露科学，流行病学， 等），以及尖端研究中使用的定量方法（生物统计学，暴露科学建模，大 数据分析等）;（2）研讨会和专题讨论会，包括文献分析和介绍主要 研究;（3）在研究的负责任的行为指令;（4）实验室研究;和（5）专业 发展，包括科学团队的沟通和矩阵管理。 研究优势包括：（1）人类环境健康，在心肺健康方面具有特定优势 发展与儿童健康、神经系统健康、癌症与环境，以及全球 （2）接触科学，重点是内分泌干扰物、药物、阻燃剂、其他 有机污染物（包括碳氢化合物）、纳米材料和无机污染物（包括金属和 类金属，和（3）环境毒理学，侧重于影响健康的分子作用机制。 UPEH计划是由杜克的医疗中心， 尼古拉斯环境学院、普拉特工程学院、全球健康研究所和Trinity 艺术和科学学院，并提供了一个独特的综合教育环境， 共享设施、支持核心和资源，以支持研究员在尖端研究方面的培训。 UPEH的核心杜克教师担任博士前学生的主要顾问。该计划是 进一步丰富了来自我们邻近的三角研究园区的兼职教师和外部顾问 除了我们的姐妹三角大学（北卡罗来纳州）之外，还有NIEHS、US EPA和RTI等机构 中央大学、北卡罗来纳州立大学和北卡罗来纳查佩尔山）。这些教职员工提供研讨会， 讲座，担任学生委员会，并提供技术专长，研究设施和职业生涯 指导我们的招聘和招生工作一直为我们提供优秀的学员， 渴望从事环境健康和相关子学科的职业，特别是 强调招聘和留住代表性不足的少数群体。我们的学生的成功后- 毕业是学生，教师和UPEH更广泛的环境质量的反映。

项目成果

Environmental Quality and Invasive Breast Cancer.

• DOI: 10.1158/1055-9965.epi-19-1497
• 发表时间: 2020-10
• 期刊: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
• 作者: Gearhart-Serna LM;Hoffman K;Devi GR
• 通讯作者: Devi GR

Voluntary commitments made by the world's largest companies focus on recycling and packaging over other actions to address the plastics crisis.

• DOI: 10.1016/j.oneear.2022.10.008
• 发表时间: 2022-11-18
• 期刊: One earth (Cambridge, Mass.)
• 作者: Diana Z;Reilly K;Karasik R;Vegh T;Wang Y;Wong Z;Dunn L;Blasiak R;Dunphy-Daly MM;Rittschof D;Vermeer D;Pickle A;Virdin J
• 通讯作者: Virdin J

Sperm DNA methylation altered by THC and nicotine: Vulnerability of neurodevelopmental genes with bivalent chromatin.

• DOI: 10.1038/s41598-020-72783-0
• 发表时间: 2020-09-29
• 期刊: Scientific reports
• 影响因子: 4.6
• 作者: Schrott R;Rajavel M;Acharya K;Huang Z;Acharya C;Hawkey A;Pippen E;Lyerly HK;Levin ED;Murphy SK
• 通讯作者: Murphy SK

Male obesity impacts DNA methylation reprogramming in sperm.

• DOI: 10.1186/s13148-020-00997-0
• 发表时间: 2021-01-25
• 期刊: Clinical epigenetics
• 影响因子: 5.7
• 作者: Keyhan S;Burke E;Schrott R;Huang Z;Grenier C;Price T;Raburn D;Corcoran DL;Soubry A;Hoyo C;Murphy SK
• 通讯作者: Murphy SK

Cleaning Up without Messing Up: Maximizing the Benefits of Plastic Clean-Up Technologies through New Regulatory Approaches.

• DOI: 10.1021/acs.est.3c01885
• 发表时间: 2023-09-12
• 期刊: ENVIRONMENTAL SCIENCE & TECHNOLOGY
• 影响因子: 11.4
• 作者: Falk-Andersson, Jannike;Rognerud, Idun;De Frond, Hannah;Leone, Giulia;Karasik, Rachel;Diana, Zoie;Dijkstra, Hanna;Ammendolia, Justine;Eriksen, Marcus;Utz, Ria;Walker, Tony R.;Furst, Kathinka
• 通讯作者: Furst, Kathinka