Structural determinants and mechanisms underlying the Major Histocompatibility Complex Class II gene-linked resistance to autoimmune diabetes
Structural determinants and mechanisms underlying the Major Histocompatibility Complex Class II gene-linked resistance to autoimmune diabetes
批准号:
461072
负责人:
Santamaria Pere
金额:
$77.47万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2022
资助国家:
加拿大
项目状态:
未结题
起止时间:
2022-03-01 至 2027-03-01
中文摘要
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英文摘要
Type 1 diabetes (T1D) results from immune dysregulation (autoimmunity) leading to destruction of the insulin-producing cells of the pancreas (beta cells) by killer white blood cells. Susceptibility and resistance to T1D are both genetically determined, bu
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