Brain Attack Surveillance in Corpus Christi (BASIC) Project

摘要 虽然美国（US）的中风发病率和死亡率正在下降，但墨西哥裔美国人仍然有一个 卒中负担更高，发生率和复发率更高，神经系统、功能和认知功能更差 结果，以及卒中后新预测的较高死亡率。墨西哥裔美国人数量最多 西班牙裔美国人的一个分支，是美国最大的少数民族。这个重要的群体正在老龄化， 迅速发展，并蔓延到全国各地。这次脑攻的更新申请 Corpus Christi（BASIC）项目的监测将促进对以下疾病进行基于人口的四分之一世纪检查： 墨西哥裔美国人和非西班牙裔白人的中风趋势，包括首次考虑 神经学、功能、认知和生活质量结局的趋势。这些数据对公共卫生至关重要 规划和监测干预措施的有效性。绝大多数中风患者 影响他们健康的中风后遗症。BASIC将首次调查 使用患者报告结局，对患者及其护理人员重要的结局 测量信息系统是在联合国系统的主持下开发的一个经过充分验证的工具， 美国国立卫生研究院和中风专家小组的建议。新的数据收集将产生 关键数据作为制定干预措施以改善卒中结局和减少卒中影响的第一步 在墨西哥裔美国人和非西班牙裔白人中。此外，我们将把十多年的数据 使用多个大型管理数据集，包括德克萨斯州住院患者研究数据文件 急诊科数据集和医疗保险数据，以研究种族特异性错过的机会， 一级和二级预防，如发现房颤但 在中风之前没有采取行动。我们亦会研究中风后的资源运用，以找出需要改善的地方 减少种族差异。总之，BASIC将继续提供唯一正在进行的， 在墨西哥裔美国人中进行不间断的中风监测;我们将重点关注种族差异和相似性， 患者报告的结果旨在设计干预措施以改善结果;我们将创建一个 中风“大数据”资源，结合BASIC验证的中风事件与详细的临床 数据和医疗保健利用信息，以预防中风和改善结果。 自2000年1月1日以来，BASIC已经积累了超过11，000名中风患者的队列，我们增加了额外的 每年450。除了丰富的出版记录和众多的衍生项目外，BASIC才刚刚开始 充分利用这一宝贵的中风患者资源。

Abstract While stroke incidence and mortality are declining in the United States (US), Mexican Americans still have a much higher stroke burden with higher incidence and recurrence, worse neurologic, functional and cognitive outcome, and newly projected higher mortality following stroke. Mexican Americans are the most numerous sub-group of Hispanic Americans, the largest minority population in the US. This important group is aging, growing rapidly, and spreading throughout the country. This renewal application of the Brain Attack Surveillance in Corpus Christi (BASIC) project will facilitate a quarter century population-based examination of stroke trends in Mexican Americans and non-Hispanic whites, including, for the first time, consideration of trends in neurologic, functional, cognitive and quality of life outcomes. This data is crucial for public health planning and monitoring the effectiveness of interventions. The overwhelming majority of stroke patients have long-term sequelae from their stroke that impact their well-being. For the first time, BASIC will investigate outcomes that are important to patients and their caregivers using the Patient-Reported Outcomes Measurement Information System (PROMIS), a well validated tool developed under the auspices of the National Institutes of Health and recommended by a stroke expert panel. This new data collection will yield critical data as the first step in developing interventions to improve stroke outcome and reduce stroke’s impact in Mexican Americans and non-Hispanic whites. Additionally, we will link more than a decade’s worth of data from BASIC with multiple large administrative datasets, including the Texas State Inpatient Research Data File and Emergency Department Dataset and Medicare data, to study ethnic-specific missed opportunities for primary and secondary prevention, such as emergency department visits where atrial fibrillation is noted but not acted upon prior to stroke. We will also examine post-stroke resource utilization to identify areas to improve stroke outcomes and reduce ethnic disparities. In sum, BASIC will continue to provide the only ongoing, uninterrupted stroke surveillance in Mexican Americans; we will focus on ethnic differences and similarities in patient reported outcomes aimed towards designing interventions to improve outcomes; and we will create a stroke “big data” resource combining the strengths of BASIC’s validated stroke events with detailed clinical data and healthcare utilization information from administrative data to prevent stroke and improve outcome. BASIC has amassed a cohort of over 11,000 stroke patients since January 1, 2000, and we add an additional 450 each year. In addition to the rich publication record and numerous spin-off projects, BASIC has just begun to fully take advantage of this precious stroke patient resource.