CLINICAL AND TRANSLATIONAL SCIENCE AWARD

哥伦比亚大学医学中心(CUMC)的CTSA计划将改变临床和 翻译(C/T)研究，以便我们能够培养和留住一支优秀的高级教职干部来领导 下一代C/T调查员。在CUMC的杰出支持下-赫伯特·欧文 捐赠，将从目前的1,500万美元增加到2,500万美元，我们将实现 我们的目标是创建欧文临床与翻译研究所(IfCTR)。国际卢旺达问题国际法庭将成为 下一代C/T研究人员的学术和智力之家。国际卢旺达问题国际法庭将有一个 优秀的高级和初级C/T调查员队伍，他们将领导资源开发以执行 RM-06-002中定义的关键功能。资深教员将为卢旺达问题国际法庭提供领导和地位， 并担任初级教员和卢旺达问题国际法庭实习生的导师。初级教员，称为欧文研究员， 将得到CUMC基金(450,000美元/年)的支持，并将与资深教员合作开发新方法 打破多学科和跨学科(M&L)C/T研究的障碍。欧文学者队将成为 M&L研究应在中央管理委员会进行的榜样，以及卢旺达问题国际法庭提供的资源， 包括在生物医学信息学、生物统计学和临床试验设计方面的杰出支持和研究， 生物伦理学、监管问题、以患者为导向的研究和核心资源，将使我们能够推动这些 改变。欧文研究员将得到CUMC以及试点和合作研究补助金的支持 由卢旺达问题国际法庭判给(70万美元/年)。卢旺达问题国际法庭将有35,000平方英尺的空间，包括6,000平方英尺的 CUMC新建造的住院/门诊研究空间(300万美元)，2200平方英尺的新空间 临床研究教育中心(100万美元)，这将是我们的实习生和 教职员工和一个新的校外研究中心，以支持基于社区的C/T研究和教育(1美元 百万)。我们已经创建了一个综合教育计划，其中包括一名新的多学科患者 定向研究硕士学位--M&L一项新颖的K12学者导师研究计划 研究，以及开创性的MPOR博士项目。将定期跟踪和评估CTSA的所有活动。 儿科和基于社区的G/T研究将受到特别关注。国际卢旺达问题国际法庭和CTSA将破裂 消除阻碍新知识从替补席向床边和社区传播的障碍。

Columbia University Medical Center's (CUMC) CTSA program will transform the culture of clinical and translational (C/T) research so that we can develop and retain an outstanding cadre of senior faculty to lead the next generation of C/T investigators. With outstanding support from the CUMC - Herbert Irving Endowment, which will increase from its present level of $15 million to $25 million dollars, we will accomplish our goal by creating the Irving Institute for Clinical and Translational Research (ifCTR). The IICTR will bethe academic and intellectual home for the next generation of C/T investigators. The IICTR will have an outstanding faculty of senior and junior C/T investigators who will lead Resources developed to carry out the Key Functions defined in RM-06-002. The senior faculty will provide leadership and stature for the IICTR, and serve as mentors for both the junior faculty and IICTR trainees. Thejunior faculty, called Irving Fellows, will be supported by CUMC funds ($450,000/y) and will work with senior faculty to develop novel approaches to breaking down the barriers to multi- and interdisciplinary (M&l) C/T research. The Irving Scholars will be role models for the way M&l research should be conducted at CUMC, and the Resources provided by IICTR, including outstanding support and research in biomedical informatics, biostatistjcal and clincal trial design, bioethics, regulatory issues, patient oriented research, and core resources, will allow us actuate those changes. The Irving Fellows will be supported by CUMC as will pilot and collaborative research grants awarded by the IICTR ($700,000/yr). The IICTR will have 35,000 sq ft of space, including 6,000 sq ft of newly constructed space for inpatient/outpatient research at CUMC ($3 million), 2,200 sq ft of new space for the Center for Clinically Oriented Research Education ($1 million) that will be a home for our trainees and faculty, and a new off-campus research center to support community-based C/T research and education ($1 million). We have created an integrated eductional program that includes a new multidisciplinary patient oriented research (MPQR) Master'sdegree, a novel K12 Scholars Mentored Research Program in M&l research, and a pioneering MPOR PhD program. All CTSA activities will be tracked and evaluated regularly. Pediatfic and community-based G/T research will receive special attention. The IICTR and CTSA will break down the barriers impeding movement of new knowledge from the bench to the bedside and community.