Parent-Infant Co-regulation of Sleep and Physiology in Families with Neglect

忽视家庭中亲子睡眠和生理的共同调节

• 批准号: 9899277
• 负责人: Samantha M Brown
• 金额: $ 13.08万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9899277
• 关键词: Address; Autonomic nervous system; Behavior; Behavior assessment; Behavioral; Biological; Biological Markers; Biological Process; Breathing; Child; Child Abuse and Neglect; Child Rearing; Child Welfare; Colorado; Consultations; Cues; Data; Data Analyses; Development; Enrollment; Exposure to; Family; Future; Goals; Grant; Health; Heart Rate; Hormones; Impaired cognition; Impairment; Incidence; Infant; Infant Behavior; Infant Development; Intervention; Intervention Studies; Longitudinal Studies; Mentored Research Scientist Development Award; Mentorship; Methodology; Methods; Mission; Mothers; Movement; National Institute of Child Health and Human Development; Nervous System Physiology; Outcome; Parents; Patient Self-Report; Pattern; Physiological; Physiology; Play; Polysomnography; Positioning Attribute; Process; Public Health; Questionnaires; Regulation; Research; Research Personnel; Research Project Grants; Resources; Respiration; Risk; Role; Science; Sleep; Sleep disturbances; Stress; System; Temperature; Testing; Time; Training; Training Programs; Transact; Translating; Translational Research; Universities; Vulnerable Populations; Work; Writing; actigraphy; adverse outcome; aged; base; behavioral health; behavioral impairment; biobehavior; career; career development; child neglect; deprivation; diaries; dissemination research; early childhood; evidence base; experience; high risk parents; improved; indexing; infant outcome; intervention program; longitudinal design; maltreatment; neglect; novel; professor; responsible research conduct; sensor; skills; sleep physiology; sleep regulation; tenure track; therapy development

PROJECT SUMMARY/ ABSTRACT The proposed K01 award will provide a 5-year training program to support Dr. Brown's career goal of becoming an independent researcher in the fields of child maltreatment, developmental science, and sleep. The K01 study will take place at Colorado State University where Dr. Brown will begin a tenure-track Assistant Professor position in August 2018. Dr. Brown will build on her skills in child maltreatment, stress physiology, and behavioral health by engaging in the following training goals: (1) develop skills in the acquisition, scoring, analysis, and interpretation of sleep and autonomic nervous system (ANS) data; (2) develop skills in parent- infant dyadic assessment and data analysis; (3) enhance expertise in translational research with families with neglect to inform the development of a child welfare intervention focused on sleep and ANS regulatory processes; and (4) engage in career development activities through grant writing, lab management, training in the responsible conduct of research, mentorship, and dissemination of research findings. Dr. Brown will receive training from Dr. LeBourgeois, an expert in early childhood and family sleep; Dr. Fifer, an expert in the assessment of infant sleep and ANS functions; Dr. Lunkenheimer, an expert in co-regulation in parents and children exposed to maltreatment; and Dr. Taussig, an expert in translational intervention research with child welfare-involved children and families. Dr. Brown will receive consultation from Dr. Garrison who will offer expertise on child and family sleep intervention development; and Dr. Sharp, who will advise on dyadic data analysis. Research Project: Early physiological and behavioral co-regulation between parent and infant supports healthy infant development and family functioning. In families with neglect, this co-regulation manifests as discordance in regulatory biomarkers between parent and infant physiology and behavior, thereby placing families at risk for maladaptive outcomes. Sleep is another core regulatory process that may be implicated in neglect and is pivotal to infant development and family functioning. Yet, current understanding of parent-infant co-regulation of sleep is limited and critical to inform potential future interventions for neglectful families. The goal of this study is to build on the extant research on physiological and behavioral co-regulation of parent-infant dyads and address the following aims: (1) to identify longitudinal patterns of parent-infant co- regulation of sleep and ANS processes in families with and without neglect; and (2) to determine the extent to which co-regulation of sleep and ANS processes can distinguish adaptive from maladaptive parent-infant outcomes in families with and without neglect. Study methods will involve a longitudinal design with self-report, physiological, and behavioral assessments of 90 parents and their infants aged 6-9 months with and without neglect. The proposed activities will have a significant impact by elucidating sleep as a novel process in the study of parent-infant co-regulation and our understanding of how sleep and autonomic regulatory processes transact over time in order to provide improved targets for intervention among high-risk parent-infant dyads.

项目摘要/摘要 拟议的K01奖项将提供一个为期5年的培训计划，以支持布朗博士的职业目标 成为虐待儿童、发展科学和睡眠领域的独立研究员。 K01研究将在科罗拉多州立大学进行，布朗博士将在那里开始担任终身教职助理 2018年8月担任教授一职。布朗博士将在虐待儿童、压力生理学、 和行为健康，通过从事以下培训目标：(1)发展技能的获得，得分， 分析和解释睡眠和自主神经系统(ANS)数据；(2)培养父母- 婴儿二元评估和数据分析；(3)与以下家庭加强翻译研究方面的专业知识 忽视通知以睡眠和ANS监管为重点的儿童福利干预的发展 过程；和(4)通过编写赠款、实验室管理、培训 负责任地进行研究、指导和传播研究成果。布朗博士会 接受勒布尔乔瓦博士的培训，他是幼儿和家庭睡眠方面的专家；菲弗博士是儿童和家庭睡眠方面的专家 对婴儿睡眠和ANS功能的评估；伦肯海默博士，父母和 儿童遭受虐待；以及陶西格博士，儿童翻译干预研究的专家 涉及福利的儿童和家庭。布朗医生将接受加里森医生的咨询，他将提供 儿童和家庭睡眠干预发展方面的专业知识；以及夏普博士，他将为二元数据提供建议 分析。研究项目：父母和婴儿之间的早期生理和行为协同调节 支持婴儿健康发展和家庭功能。在被忽视的家庭中，这一共同规则 表现为父母和婴儿的生理和行为之间的调节生物标志物不一致，从而 使家庭面临适应不良后果的风险。睡眠是另一个核心的调节过程，可能是 与忽视有牵连，对婴儿发育和家庭功能至关重要。然而，目前对 父母和婴儿对睡眠的共同调节是有限的，对于为疏忽提供潜在的未来干预措施至关重要 家人。这项研究的目的是在现有的生理和行为协同调节研究的基础上 并解决以下目标：(1)确定亲子共同的纵向模式 对有疏忽和无疏忽的家庭的睡眠和ANS过程的调节；以及(2)确定 睡眠和ANS过程的哪种共同调节可以区分适应性和适应性不良的亲子 有无疏忽的家庭的结果。研究方法包括纵向设计和自我报告， 90名父母及其6~9个月婴儿的生理和行为评估 忽视。拟议的活动将通过阐明睡眠作为一种新的过程而产生重大影响 亲子共同调节的研究及其对睡眠和自主调节过程的理解 随着时间的推移进行处理，以便为高危父母-婴儿二人组提供更好的干预目标。