Cancer Prevention, Control, and Population Research Program

癌症预防、控制和人口研究(CPC)计划 项目摘要/摘要 癌症预防、控制和人口研究(CPC)计划的目标是开发和 评估降低癌症发病率和改善癌症预后的干预措施 综合癌症中心(Case CCC)集水区及更远地区。计划成员创建小说 减少风险、筛查和早期发现的方法。他们还进行研究，以实施和 监测建议的预防服务、治疗和癌症后生存护理的改进提供情况 诊断。该计划围绕三个科学目标组织：(1)发现战略并制定和 实施行为干预，以降低癌症风险，改善癌症诊断后的预后；(2) 评估和促进有效的癌症筛查、监测和治疗政策及其对 实践和保健系统；以及(3)发现和描述遗传和环境因素 与癌症有关。这些目标反映了主要的工作组和倡议，将计划成员与 其他癌症中心研究人员通过项目间合作影响了 病人护理、健康政策和更大的癌症研究社区。广泛使用共享数组 资源，特别是生物统计学、癌症结果、基因组学和组织促进成员的方方面面 发现。 在格雷戈里·库珀(联合领导人)和苏珊·弗洛克(联合领导人)的领导下，CPC计划有38 会员包括30名正式会员、1名准会员和7名临床会员。成员代表20个部门，给予 增加到1080万美元的赠款资金(年度直接成本)，其中820万美元是同行审查，230万美元是 NCI资助的。2012至2016年间，中共计划成员出版了1174份出版物。癌症和 与方案有关的出版物包括25%的方案间出版物，16%的方案内出版物，6%的方案间和方案内出版物 计划性的和11%的涉及与另一个癌症中心的合作。这是非常有效的 计划成功地在Case CCC CPC成员之间创造了协同效应，并与 服务不足地区癌症预防的新举措证明了其他研究项目的研究人员 城市人口、烟草控制、结肠癌筛查和预防的新方法、姑息治疗 晚期癌症患者的风险，以及艾滋病毒感染者的癌症风险。

CANCER PREVENTION, CONTROL AND POPULATION RESEARCH (CPC) PROGRAM PROJECT SUMMARY/ABSTRACT The goal of the Cancer Prevention, Control and Population Research (CPC) Program is to develop and evaluate interventions that reduce the incidence and improve the outcomes of cancer in the Case Comprehensive Cancer Center (Case CCC) catchment area and beyond. Program members establish novel approaches in risk reduction, screening, and early detection. They also conduct research to implement and monitor improved delivery of recommended preventive services, therapies, and survivorship care after cancer diagnosis. The program is organized around 3 scientific aims: (1) Discover strategies and develop and implement behavioral interventions to reduce cancer risk and improve outcomes after cancer diagnosis; (2) Evaluate and facilitate effective cancer screening, surveillance and treatment policies and their impact on practice and the healthcare system; and (3) Discover and characterize genetic and environmental factors linked to cancer. These aims reflect major working groups and initiatives that coalesces program members with other cancer center investigators through inter-programmatic collaborations that have impacted paradigms for patient care, health policy and the larger cancer research community. Extensive use of an array of shared resources, in particular Biostatistics, Cancer Outcomes, Genomics, and Tissue facilitate all aspects of member discoveries. Under the leadership of Gregory Cooper (Co-Leader) and Susan Flocke (Co-Leader) the CPC Program has 38 members including 30 full, 1 associate, and 7 clinical members. Members represent 20 departments, giving rise to a total of $10.8M in grant funding (annual direct costs), of which $8.2M is peer-reviewed and $2.3M is NCI-funded. Between 2012 and 2016, CPC program members published 1,174 publications. Cancer and program related publications included 25% inter-programmatic, 16% intra-programmatic, 6% inter- and intra- programmatic and 11% that involved collaborations with another Cancer Center. This highly effective Program has successfully created synergy among Case CCC CPC members and collaborations with investigators in other research Programs as evidenced by new initiatives in cancer prevention in underserved urban populations, tobacco control, new approaches to colon cancer screening and prevention, palliative care of patients with advanced cancer, and cancer risk in HIV infected individuals.