Cancer Prevention, Control, and Population Research Program

癌症预防、控制和人口研究（CPC） 项目总结/摘要 癌症预防、控制和人口研究计划（CPC）的目标是发展和 评估干预措施，降低发病率和改善癌症的结果， 综合癌症中心（案例CCC）集水区及以外。计划成员建立小说 减少风险、筛查和早期发现的方法。他们还进行研究， 监测癌症后推荐的预防服务、治疗和生存护理的改善情况 诊断.该计划围绕3个科学目标组织：（1）发现战略和发展， 实施行为干预以降低癌症风险并改善癌症诊断后的结果;（2） 评估和促进有效的癌症筛查、监测和治疗政策及其对 实践和医疗保健系统;（3）发现和表征遗传和环境因素 与癌症有关这些目标反映了主要的工作组和倡议， 其他癌症中心的研究人员通过跨计划的合作，影响了范式， 病人护理、卫生政策和更大的癌症研究界。广泛使用一系列共享 资源，特别是生物统计学，癌症结果，基因组学和组织促进成员的各个方面 发现。 在格雷戈里库珀（联合领导人）和苏珊弗洛克（联合领导人）的领导下，CPC计划有38个 成员包括30名正式成员、1名准成员和7名临床成员。成员来自20个部门， 增加到1080万美元的赠款资金（年度直接费用），其中820万美元是同行评审的，230万美元是 国家癌症研究所资助在2012年至2016年期间，CPC计划成员出版了1，174份出版物。癌症和 与计划相关的出版物包括25%的计划间出版物，16%的计划内出版物，6%的计划间和计划内出版物。 11%涉及与另一个癌症中心的合作。这种高效的 该计划成功地在Case CCC CPC成员之间创造了协同效应，并与 其他研究项目的研究人员，如在服务不足的地区预防癌症的新举措所证明的那样。 城市人口，烟草控制，结肠癌筛查和预防的新方法，姑息治疗 和HIV感染者的癌症风险。

CANCER PREVENTION, CONTROL AND POPULATION RESEARCH (CPC) PROGRAM PROJECT SUMMARY/ABSTRACT The goal of the Cancer Prevention, Control and Population Research (CPC) Program is to develop and evaluate interventions that reduce the incidence and improve the outcomes of cancer in the Case Comprehensive Cancer Center (Case CCC) catchment area and beyond. Program members establish novel approaches in risk reduction, screening, and early detection. They also conduct research to implement and monitor improved delivery of recommended preventive services, therapies, and survivorship care after cancer diagnosis. The program is organized around 3 scientific aims: (1) Discover strategies and develop and implement behavioral interventions to reduce cancer risk and improve outcomes after cancer diagnosis; (2) Evaluate and facilitate effective cancer screening, surveillance and treatment policies and their impact on practice and the healthcare system; and (3) Discover and characterize genetic and environmental factors linked to cancer. These aims reflect major working groups and initiatives that coalesces program members with other cancer center investigators through inter-programmatic collaborations that have impacted paradigms for patient care, health policy and the larger cancer research community. Extensive use of an array of shared resources, in particular Biostatistics, Cancer Outcomes, Genomics, and Tissue facilitate all aspects of member discoveries. Under the leadership of Gregory Cooper (Co-Leader) and Susan Flocke (Co-Leader) the CPC Program has 38 members including 30 full, 1 associate, and 7 clinical members. Members represent 20 departments, giving rise to a total of $10.8M in grant funding (annual direct costs), of which $8.2M is peer-reviewed and $2.3M is NCI-funded. Between 2012 and 2016, CPC program members published 1,174 publications. Cancer and program related publications included 25% inter-programmatic, 16% intra-programmatic, 6% inter- and intra- programmatic and 11% that involved collaborations with another Cancer Center. This highly effective Program has successfully created synergy among Case CCC CPC members and collaborations with investigators in other research Programs as evidenced by new initiatives in cancer prevention in underserved urban populations, tobacco control, new approaches to colon cancer screening and prevention, palliative care of patients with advanced cancer, and cancer risk in HIV infected individuals.