IGF::OT::IGF BIOINFORMATICS SUPPORT FOR THE NIEHS IN DIR & DNTP

IGF::OT::IGF 生物信息学支持 DIR 中的 NIEHS

• 批准号: 9915697
• 负责人: RUCHIR SHAH
• 金额: $ 246.4万
• 依托单位: SCIOME, LLC
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-03-24 至 2020-03-23
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9915697
• 关键词: Artificial Intelligence; Bioinformatics; Biological Assay; ChIP-seq; Chemical Exposure; Chemicals; Contractor; Contracts; DNA Methylation; DNA Sequence; DNA sequencing; Data; Data Analyses; Data Set; Databases; Development; Epigenetic Process; Evaluation; Exons; Gene Expression; Genes; Genomics; Informatics; Intramural Research; Knowledge; Laboratories; Literature; Measures; Mining; National Institute of Environmental Health Sciences; National Toxicology Program; Output; Pathway Analysis; Peer Review; Privatization; Programming Languages; Proteomics; Publications; Research; Research Design; Research Personnel; Resources; Sampling; Scientific Evaluation; Scientist; Series; Software Tools; Specific qualifier value; Technology; Text; Toxicogenomics; Toxicology; analysis pipeline; bioinformatics tool; bisulfite sequencing; cheminformatics; computational intelligence; data integration; data mining; differential expression; high throughput screening; innovation; meetings; metabolomics; method development; next generation sequencing; physical property; programs; screening; technique development; transcriptomics; whole genome

The purpose of this contract is to provide bioinformatic support to researchers in the Divisions of National Toxicology Program (DNTP) and Intramural Research (DIR) at the National Institute of Environmental Health Sciences (NIEHS). NIEHS researchers conduct studies that produce large amounts of data, varying in size and complexity. Fields of scientific study are diverse and include toxicology, genomics, transcriptomics, high throughput screening (HTS) data and data extraction from diverse text resources. The variety and complexity of NIEHS scientific studies dictates the need for innovative analytical techniques and the development of new software tools. Bioinformatic data analyses are required to support accurate and precise interpretation of study results. Specific bioinformatics needs include data analysis, data mining, creating bioinformatics pipelines for gene expression and pathway analysis and computational support for the vast amount of data collected through studies conducted at NIEHS and NIEHS contract laboratories.

该合同的目的是为国家环境健康科学研究所（NIEHS）国家毒理学计划（DNTP）和校内研究（INTRUNK）部门的研究人员提供生物信息学支持。NIEHS的研究人员进行的研究产生了大量的数据，大小和复杂性各不相同。科学研究的领域是多样的，包括毒理学，基因组学，转录组学，高通量筛选（HTS）数据和数据提取从不同的文本资源。NIEHS科学研究的多样性和复杂性决定了对创新分析技术和新软件工具开发的需求。需要生物信息学数据分析来支持对研究结果的准确和精确的解释。具体的生物信息学需求包括数据分析、数据挖掘、为基因表达和途径分析创建生物信息学管道，以及为通过在NIEHS和NIEHS合同实验室进行的研究收集的大量数据提供计算支持。