IGF::OT::IGF BIOINFORMATICS SUPPORT FOR THE NIEHS IN DIR & DNTP

该合同的目的是为国家环境健康科学研究所（NIEHS）的国家毒理学计划（DNTP）和校内研究（DIR）部门的研究人员提供生物信息学支持。NIEHS的研究人员进行的研究产生了大量数据，这些数据的大小和复杂性各不相同。科学研究的领域是多种多样的，包括毒理学、基因组学、转录组学、高通量筛选（HTS）数据和从各种文本资源中提取数据。NIEHS科学研究的多样性和复杂性决定了对创新分析技术和新软件工具开发的需求。需要生物信息学数据分析来支持准确和精确的研究结果解释。具体的生物信息学需求包括数据分析、数据挖掘、为基因表达和途径分析创建生物信息学管道，以及为NIEHS和NIEHS合同实验室通过研究收集的大量数据提供计算支持。

The purpose of this contract is to provide bioinformatic support to researchers in the Divisions of National Toxicology Program (DNTP) and Intramural Research (DIR) at the National Institute of Environmental Health Sciences (NIEHS). NIEHS researchers conduct studies that produce large amounts of data, varying in size and complexity. Fields of scientific study are diverse and include toxicology, genomics, transcriptomics, high throughput screening (HTS) data and data extraction from diverse text resources. The variety and complexity of NIEHS scientific studies dictates the need for innovative analytical techniques and the development of new software tools. Bioinformatic data analyses are required to support accurate and precise interpretation of study results. Specific bioinformatics needs include data analysis, data mining, creating bioinformatics pipelines for gene expression and pathway analysis and computational support for the vast amount of data collected through studies conducted at NIEHS and NIEHS contract laboratories.