Conduct of mechanistic studies on radio frequency radiation (RFR) for the NTP

该项目的目标是为国家毒理学计划（NTP）的危害识别活动提供支持，这些活动旨在预防因环境暴露于化学或物理制剂而引起的疾病或不良影响。毒性测试是公共卫生研究的一个重要方面，因为它有助于确定对人类健康有害的化学品。需要适当进行毒理学研究，以确保所得数据可靠。NTP最近报告了对手机使用的频率和调制的射频辐射的毒性和致癌性研究结果。大鼠的频率为900 MHz，小鼠的频率为1900 MHz。调制方式为GSM和CDMA。每天暴露9小时10分钟，持续18小时20分钟（10分钟开/10分钟关）。这些研究的目的是对射频辐射进行后续的机理研究。这些研究将解决在致癌性研究的实施和报告期间提出的问题，并将机理理解扩展到其他调节/暴露情景。该项目的数据最终将使人们更好地了解大鼠和小鼠的毒性和致癌性研究，并支持国家毒理学计划和其他联邦机构的风险评估工作。 关键词：射频辐射，CDMA，GSM，调制，频率

The goal of this project is to provide support of National Toxicology Program (NTP) hazard identification activities targeted toward the prevention of diseases or adverse effects caused by environmental exposure to chemical or physical agents. Toxicity testing is an important aspect of public health research in that it serves to identify chemicals that are hazardous to human health. Proper conduct of toxicology studies is required to ensure that the resulting data are reliable. The NTP recently reported the results of toxicity and carcinogenicity studies of radio frequency radiation at frequencies and modulations used by cell phones. Frequencies were 900 MHz in rats and 1900 MHz in mice. Modulations were GSM and CDMA. Exposures were 9 hr 10 min over an 18 hr 20 min period each day (10 min on/10 min off). The goal of these studies is to conduct follow on mechanistic studies on radio frequency radiation. These studies will address questions raised during conduct and reporting of the carcinogenicity studies and extend mechanistic understanding to additional modulations/exposure scenarios. Data from this project will ultimately allow a greater understanding of the toxicity and carcinogenicity studies in rats and mice and support the risk assessment efforts of National Toxicology Program and other federal agencies. Keywords: radio frequency radiation, CDMA, GSM, modulation, frequency