Trace Element Analysis Core
微量元素分析核心
基本信息
- 批准号:9921558
- 负责人:
- 金额:$ 33.54万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:
- 资助国家:美国
- 起止时间:至
- 项目状态:未结题
- 来源:
- 关键词:AblationAddressAnalytical ChemistryAnimal OrganArsenicBiologicalBiological AvailabilityBiological MarkersBirthBloodCellsCohort StudiesCollaborationsComplexContractsCoupledDataData AnalyticsDetectionDevelopmentEarth scienceEducational process of instructingEnsureEnvironmentEnvironmental Risk FactorEpidemiologistExposure toFishesFoodFosteringGas ChromatographyGoalsGrainHairHealthHumanHuman MilkHuman ResourcesImageIndividualInductively Coupled Plasma Mass SpectrometryInfantInterdisciplinary StudyInternationalInvertebratesJuiceLaboratoriesLasersLettersLightLiquid ChromatographyMeconiumMercuryMetalsMethodologyMethodsMethylmercury CompoundsMissionMusNew HampshirePaperPostdoctoral FellowPreparationProceduresProcessProductionProtocols documentationPublicationsQuality ControlResearchResearch PersonnelRiceRiskSamplingSchemeServicesSignal Recognition ParticleSoilSourceStructure of nail of toeSuperfundSurfaceSuspensionsSynchrotronsSystemTechniquesTestingTimeTissuesToxic effectTrace ElementsTrace metalTrainingUrineWateranalytical methodanimal tissuebasebioimagingbiological systemscase-by-case basisearly life exposureexperienceexposed human populationgraduate studentinnovationinstrumentationmethod developmentmid-career facultynovelprogramsquality assuranceresponse
项目摘要
Trace Elements Analysis Core: Abstract
The primary goal of the Trace Element Analysis (TEA) core is to provide low level trace element analysis and
speciation and analytical chemistry expertise to Dartmouth SRP researchers to allow them to successfully
complete the aims of their individual projects. Additionally, the TEA core strives to be at the forefront of
(mission-related) method development that augments the themes of the Dartmouth SRP projects and
advances these projects by providing analytical advances such as lower detection limits, quantification of as
yet unmeasured metal species, and the novel application of an analytical methodology. The TEA core utilizes
state of the art analytical instrumentation based on inductively coupled plasma mass spectrometry (ICP-MS) to
provide low level determinations of trace elements in a variety of biological and environmental matrices. The
TEA core also provides speciation analysis for arsenic and mercury by liquid chromatography and gas
chromatography coupled to ICP-MS, respectively. The core strives to provide accurate, precise and validated
data to support Dartmouth Superfund Projects and employs a quality control program commensurate with that
expected of US EPA contract laboratories. The TEA core participates in national and international proficiency
testing to ensure the accuracy of its analytical procedures and has been subject to both internal and external
review processes to ensure it is providing useful analytical services in a timely manner. The core develops
analytical methods such as 2D elemental imaging of biological samples by laser ablation-ICP-MS or extraction
and determination of arsenic species in foods and juices to support projects 1 and 4. The core serves project 2
by providing new instrumentation and expertise for ultra-low level mercury determination and speciation. The
core also serves project 3 and 4 by the determination of arsenic concentration and speciation in water,
biological tissues and cell suspensions and lysates.
微量元素分析核心:摘要
微量元素分析(TEA)核心的主要目标是提供低水平的微量元素分析,
向达特茅斯SRP研究人员提供物种形成和分析化学专业知识,使他们能够成功地
完成各自项目的目标。此外,TEA核心致力于走在最前沿,
(与任务相关的)方法开发,增强了达特茅斯战略研究计划项目的主题,
通过提供更低的检测限,定量分析,
尚未测量的金属物种,以及分析方法的新应用。TEA核心利用
基于电感耦合等离子体质谱(ICP-MS)的现有技术分析仪器,
提供各种生物和环境基质中微量元素的低水平测定。的
TEA岩心还提供了砷和汞的液相色谱和气相色谱形态分析
分别通过色谱法偶联ICP-MS进行分析。核心致力于提供准确、精确和经过验证的
数据来支持达特茅斯超级基金项目,并采用与之相称的质量控制程序
美国环保署合同实验室的预期。TEA核心参与国家和国际水平
测试,以确保其分析程序的准确性,并已受到内部和外部
审查流程,以确保及时提供有用的分析服务。核心发展
分析方法,例如通过激光烧蚀-ICP-MS或萃取对生物样品进行2D元素成像
以及确定食品和果汁中的砷种类,以支持项目1和4。核心服务于项目2
为超低水平汞测定和形态分析提供新的仪器和专门知识。的
CORE还通过测定水中的砷浓度和形态来服务于项目3和4,
生物组织和细胞悬浮液和裂解物。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Brian P Jackson其他文献
Brian P Jackson的其他文献
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{{ truncateString('Brian P Jackson', 18)}}的其他基金
Laser Ablation-ICPTOF for fast multi-element imaging of biomedical samples
用于生物医学样品快速多元素成像的激光烧蚀-ICPTOF
- 批准号:
10427847 - 财政年份:2022
- 资助金额:
$ 33.54万 - 项目类别:
Biomedical National Elemental Imaging Resource (BNEIR)
生物医学国家元素成像资源 (BNEIR)
- 批准号:
10191567 - 财政年份:2021
- 资助金额:
$ 33.54万 - 项目类别:
Biomedical National Elemental Imaging Resource (BNEIR)
生物医学国家元素成像资源 (BNEIR)
- 批准号:
10614502 - 财政年份:2021
- 资助金额:
$ 33.54万 - 项目类别:
Laying the Groundwork for Web-based Elemental Imaging Software: The MicroAnalysis Toolkit
为基于网络的元素成像软件奠定基础:微观分析工具包
- 批准号:
10609200 - 财政年份:2021
- 资助金额:
$ 33.54万 - 项目类别:
Biomedical National Elemental Imaging Resource (BNEIR)
生物医学国家元素成像资源 (BNEIR)
- 批准号:
10392988 - 财政年份:2021
- 资助金额:
$ 33.54万 - 项目类别:
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