Excitation and inhibition in visual processing

视觉处理中的兴奋和抑制

• 批准号: 9919554
• 负责人: Nicholas J Priebe
• 金额: $ 50.62万
• 依托单位: UNIVERSITY OF TEXAS AT AUSTIN
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-30 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9919554
• 关键词: Address; Afferent Neurons; Animal Behavior; Architecture; Area; Autopsy; Behavior; Behavioral; Biological Models; Calcium; Callithrix; Cells; Complex; Cues; Electrophysiology (science); Elements; Environment; Esthesia; Eye Movements; Genomics; Goals; Image; Individual; Injections; Knowledge; Label; Location; Measurement; Measures; Membrane Potentials; Modeling; Motion; Nature; Neurons; Neurosciences; Pattern; Physiological; Population; Primates; Process; Property; Role; Sensory; Shapes; Signal Transduction; Stimulus; System; Testing; V1 neuron; Viral; Visual; Visual Cortex; Visual Motion; Visual system structure; Work; area MT; experimental study; extracellular; immunocytochemistry; neural circuit; neurochemistry; novel; object motion; orientation selectivity; relating to nervous system; response; sensory input; sensory integration; sensory mechanism; sensory system; two photon microscopy; visual processing

Project Summary A fundamental goal of systems neuroscience is to describe how sensory inputs are integrated and guide an animal's behavior. To be able to integrate these inputs, early sensory systems have developed selectivities for specific stimulus features that allow them to analyze the inputs using these features as basis. A classic example is the emergence of orientation selectivity within the visual cortex (Hubel and Wiesel, 1962). Successive processing stages in the early visual system perform systematic transformations on the incoming inputs that enable them to be able to identify multiple aspects of the visual scene important for guiding an animal's behavior, including the location, shape, depth and motion of objects. While the unique feature selectivities emerging at different stages in visual processing are known to a certain extent, the nature and mechanisms of these sensory transformations less well-understood. We aim to uncover how disparate motion signals are integrated to produce a global percept of motion, and to understand the conditions in which such integration fails.

项目总结