Mechanistic Effects of Health Coaching to reduce COPD Hospitalizations

健康指导减少慢性阻塞性肺病住院的机制效应

• 批准号: 9922140
• 负责人: Roberto Pablo Benzo
• 金额: $ 12.04万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9922140
• 关键词: Award; Behavior Therapy; Breathing; Chronic Disease; Chronic Obstructive Airway Disease; Chronic lung disease; Clinic; Clinical Investigator; Clinical Sciences; Critical Care; Development; Disease; Effectiveness; Environment; Epidemiology; Equation; Faculty; Fellowship; Funding; Future; Goals; Grant; Health; Health Benefit; Hospitalization; Intervention; K-Series Research Career Programs; Knowledge; Lung; Lung diseases; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Midcareer Investigator Award in Patient-Oriented Research; Modeling; National Heart, Lung, and Blood Institute; Outcome; Patients; Physical activity; Physicians; Publications; Publishing; Pulmonology; Quality of life; Randomized; Reporting; Research; Research Design; Research Institute; Research Personnel; Resources; Risk Assessment; Schools; Science; Small Business Innovation Research Grant; Source; Structure; Students; Testing; Time; Training; Translational Research; United States; United States National Institutes of Health; Universities; Work; base; clinical center; graduate student; health care service utilization; high risk; hospital readmission; interest; intervention effect; mid-career faculty; mindfulness; news; next generation; patient oriented; patient oriented research; persistent symptom; programs

PROJECT SUMMARY/ABSTRACT The overarching goal of the proposed research is to study further aspects of health coaching, an intervention that led to the first randomized evidence that health coaching reduces re-hospitalizations in chronic obstructive lung disease (COPD). The proposed study of the mechanistic effect of this intervention will lead to the creation of a theoretical framework of how the intervention works. We will further test the effect of health coaching on the quality of life and daily physical activity of a patient with severe symptoms of COPD in a small but powered randomized study. General goals: The proposal will provide Roberto Benzo, MD, MSc, with protected time to extend his mentorship of junior future NHLBI researchers and also expand his research program. Specific aims: Dr. Benzo plans to increase his time mentoring investigators from the Pulmonary Medicine and Critical Care Program at Mayo Clinic, students from the Mayo Clinic Graduate School of Biomedical Sciences, and Mayo Center for Clinical and Translational Science scholars. He will also perform the mechanistic analysis of his recent NHLBI-funded randomized study identifying the benefits of health coaching which decreases hospitalizations for COPD and expand the study of the effectiveness of health coaching in another disease group. Qualifications: Dr. Benzo is a tenured Associate Professor at Mayo Clinic, with a strong record of research, publication, and mentoring. His K23 career development award, training in epidemiology at Harvard University, two subsequent R01s, and multiple SBIRs have developed his background as an ideal candidate for this application. He currently leads the Mindful Breathing Lab at Mayo Clinic, an NIH-funded lab devoted to patient-oriented research in lung disease. Environment: The proposed K24 grant will be executed through the Division of Pulmonary and Critical Care at Mayo Clinic, which was ranked #1 in the United States in the last two consecutive years by the U.S. News & World Report. Mentoring program: Dr. Benzo presently mentors junior faculty, pulmonary and critical care fellows, resident physicians, and graduate students. Several mentees are engaged in NHLBI research, including one who was recently awarded a K23 from the NHLBI. Mentees: Dr. Benzo will solidify and expand his mentoring program with the assistance of this grant. The program's resources and reputation will attract an increasing pool of the most qualified and promising future NHLBI researchers. Training: Dr. Benzo will undertake substantive training to plan, execute, and analyze patient- oriented studies. Research: The proposed research will build on Dr. Benzo's previous work, especially the published findings of his recent NHLBI-funded R01 study. Significance: This grant will facilitate the development of the next generation of NHLBI patient-oriented researchers and will support the ongoing research implementing the intervention that focuses on what matters to patients.

项目概要/摘要 拟议研究的总体目标是进一步研究健康指导，一种干预措施 这导致了第一个随机证据表明健康指导可以减少慢性阻塞性肺疾病的再住院率 肺部疾病（慢性阻塞性肺病）。对这种干预的机械效应的拟议研究将导致创造 干预如何发挥作用的理论框架。我们将进一步测试健康辅导的效果 患有严重慢性阻塞性肺病 (COPD) 症状的患者在小型但动力充足的环境中的生活质量和日常体力活动 随机研究。总体目标：该提案将为医学博士、理学硕士 Roberto Benzo 提供受保护的时间 延长他对未来 NHLBI 研究人员的指导，并扩大他的研究计划。具体的 目标：Benzo 博士计划增加指导肺科和重症医学科研究人员的时间 梅奥诊所的护理计划、梅奥诊所生物医学科学研究生院的学生，以及 梅奥临床和转化科学中心的学者。他还将进行机械分析 他最近由 NHLBI 资助的随机研究确定了健康指导的好处，可以减少 因慢性阻塞性肺病住院并扩大健康指导对另一种疾病的有效性的研究 团体。资格： Benzo 博士是梅奥诊所的终身副教授，在以下领域拥有丰富的经验： 研究、出版和指导。他获得 K23 职业发展奖，在哈佛大学接受流行病学培训 大学、随后的两次 R01 和多个 SBIR 已将他的背景发展为理想的候选人 对于这个应用程序。他目前领导梅奥诊所的正念呼吸实验室，这是一个由 NIH 资助的实验室，致力于 以患者为导向的肺部疾病研究。环境：拟议的 K24 拨款将通过 梅奥诊所的肺科和重症监护科，去年在美国排名第一 连续两年被《美国新闻与世界报道》评为。导师计划： Benzo 博士目前担任导师 初级教师、肺科和重症监护研究员、住院医师和研究生。多名学员 从事 NHLBI 研究，其中包括最近获得 NHLBI 颁发的 K23 的一名人员。学员： Benzo 博士将在这笔赠款的帮助下巩固和扩大他的指导计划。该计划的 资源和声誉将吸引越来越多最合格、最有前途的未来 NHLBI 人才 研究人员。培训：Benzo 博士将接受实质性培训，以计划、执行和分析患者- 定向研究。研究：拟议的研究将建立在 Benzo 博士之前的工作基础上，特别是 发表了他最近由 NHLBI 资助的 R01 研究的结果。意义：这笔赠款将有利于 培养下一代 NHLBI 以患者为中心的研究人员，并将支持正在进行的 研究实施干预措施，重点关注对患者重要的事情。