University of Michigan Training Program in ELSI Research

密歇根大学 ELSI 研究培训计划

• 批准号: 9924618
• 负责人: Scott ROBERTS
• 金额: $ 25.87万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-07 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9924618
• 关键词: Michigan; Research; Training Programs; Universities

ABSTRACT Genetics and genomics research are rapidly generating scientific discoveries, technological advances, and clinical applications, each with important implications for medicine and public health. In order for the promise of the “genomics revolution” to be achieved, however, numerous ethical, legal and social implications (ELSI) will need to be proactively addressed. Since 1990, the National Human Genome Research Institute (NHGRI) has funded an ELSI Research Program focused on areas including ethical dilemmas in genomics research, integration of genetic testing in healthcare settings, and legal, regulatory and public policy challenges. The ELSI Program's recent inclusion in the broader NIH Institutional Training Grants Program (T32) signals a recognition of the need to train the next generation of ELSI researchers to face the growing challenges and opportunities posed by advances in genomics research. The University of Michigan (UM) Training Program in ELSI Research will help meet this need by providing integrated, interdisciplinary instruction for predoctoral and postdoctoral scholars. We propose to support two predoctoral and two postdoctoral fellows per year. Each fellow will participate in an individualized, 2-year course of training that will provide mentoring, knowledge and skills in areas including 1) the current state of genomic science and medicine; 2) core principles and frameworks in bioethics; 3) quantitative and qualitative research methods; 4) grant writing and manuscript preparation; and 5) the implementation of interdisciplinary ELSI research projects. The training program will be based in the UM School of Public Health, in close collaboration with units in the UM Medical School including the Center for Bioethics & Social Sciences in Medicine, and the Department of Human Genetics. The training program will feature a team of 18 faculty mentors with vast experience in ELSI research and/or clinical genetics and a proven track record of NIH- funded projects and research mentoring; these mentors possess expertise across relevant disciplines including bioethics, clinical psychology, genetic counseling, genetic health / risk communication, health education, health law, health services research, medical decision-making, medical genetics, medical sociology, oncology, pediatrics, public policy, science / technology studies, and statistical genetics. The proposed training program will also draw upon the considerable resources of the University of Michigan, including the career development programs of the Michigan Institute for Clinical & Health Research, research methods training opportunities at the Institute for Social Research, and institutional support from the Rackham Graduate School.

抽象的 遗传学和基因组学研究正在迅速产生科学发现、技术进步和 临床应用，每个对医学和公共卫生都有重要影响。为了兑现承诺 然而，要实现的“基因组革命”将带来许多伦理、法律和社会影响（ELSI） 需要积极解决。自 1990 年以来，国家人类基因组研究所 (NHGRI) 资助了 ELSI 研究计划，重点关注基因组学研究中的道德困境等领域， 将基因检测纳入医疗保健环境，以及法律、监管和公共政策挑战。这 ELSI 计划最近被纳入更广泛的 NIH 机构培训资助计划 (T32)，这标志着 认识到需要培训下一代 ELSI 研究人员以应对日益增长的挑战， 基因组学研究的进步带来的机遇。 密歇根大学 (UM) 的 ELSI 研究培训计划将通过提供以下服务来帮助满足这一需求： 为博士前和博士后学者提供综合、跨学科的指导。我们建议支持两个 每年招收博士前研究员和两名博士后研究员。每个研究员将参加一个为期 2 年的个性化项目 培训课程将提供以下领域的指导、知识和技能：1）当前状态 基因组科学和医学； 2）生物伦理学的核心原则和框架； 3）定量和定性 研究方法； 4）资助写作和稿件准备； 5）跨学科的实施 ELSI 研究项目。培训计划将设在密西根大学公共卫生学院， 与密歇根大学医学院的单位合作，包括生物伦理与社会科学中心 医学和人类遗传学系。该培训计划将由 18 名教师组成的团队参加 导师在 ELSI 研究和/或临床遗传学方面拥有丰富的经验，并且在 NIH- 方面拥有良好的记录 资助项目和研究指导；这些导师拥有相关学科的专业知识，包括 生物伦理学、临床心理学、遗传咨询、遗传健康/风险沟通、健康教育、健康 法律、卫生服务研究、医疗决策、医学遗传学、医学社会学、肿瘤学、 儿科、公共政策、科学/技术研究和统计遗传学。拟议的培训计划 还将利用密歇根大学的大量资源，包括职业发展 密歇根临床与健康研究所的项目，研究方法培训机会 社会研究所和拉克姆研究生院的机构支持。