Maintenance and Enhancement of ISO/IEC 17025 Accreditation and Whole Genome Sequencing for State Food Testing Laboratories (U18 Clinical Trial Not Allowed)

国家食品检测实验室ISO/IEC 17025认证和全基因组测序的维护和加强（不允许U18临床试验）

• 批准号: 9933420
• 负责人: Willis M. Fedio
• 金额: $ 16.5万
• 依托单位: NEW MEXICO STATE UNIVERSITY LAS CRUCES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-05 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9933420
• 关键词: Maintenance; Enhancement; ISO; IEC; 17025

Project Summary From 1999-2014, the Food Safety Laboratory (FSL), Center for Animal Health, and Food Safety at New Mexico State University (NMSU) has worked closely with the Food and Drug Administration (FDA) Office of Field Science on a variety of food safety and defense assignments. Since then we have been working with the FDA as a FERN Laboratory, a FERN MCAP Laboratory and GenomTrackr Laboratory. The NMSU FSL was tasked by the FDA ORA to evaluate, analyze and validate rapid test methods. We have improved many Bacteriological Analytical Manual (BAM) methods and provided validation data for rapid methods that have been implemented by FDA Regional Laboratories. FDA has also distributed improvements in analytical methods to Food Emergency Response Network (FERN) member laboratories. We are directly involved in many of the FERN mission objectives. We provide laboratory outreach with New Mexico State University agricultural programs to growers and food processors. We have demonstrated experience in method development and validation. Through the New Mexico Cooperative Extension Service Programs, we provide training to growers and food processors in food safety and defense. We perform regular proficiency testing and validation with BAM and new rapid test methods. When requested, we participate in surveillance activities. We are a member of the Electronic Laboratory Exchange Network (eLEXNET) Program for electronic communications. In 2014, we joined the FDA Whole Genome Project and obtained an illumina MiSeq benchtop sequencer and supplies for sequencing from CFSAN. The NMSU FSL plans to continue sequencing pathogenic microorganisms for the FDA through the GenomTrakr network and NCBI. As a GenomTrakr lab, we intend to continue to: 1) Sequence 400 isolates/year 2) Participate in proficiency tests and other FERN/FDA activities as requested 3) Participate in GenomTrakr semiannual meetings

项目摘要 1999-2014年间，纽约食品安全实验室(FSL)动物健康和食品安全中心 墨西哥州立大学(NMSU)与食品和药物管理局(FDA)办公室密切合作 田野科学部负责各种食品安全和防御任务。从那时起，我们一直在努力 FDA作为蕨类实验室，蕨类MCAP实验室和GenomTrackr实验室。 NMSU FSL受命于FDA ORA来评估、分析和验证快速测试方法。我们 改进了许多细菌分析手册(BAM)方法，并为 FDA区域实验室已经实施的快速方法。FDA还分发了 粮食应急网络(FERN)成员分析方法的改进 实验室。 我们直接参与了许多费恩任务的目标。我们为您提供实验室外展服务 新墨西哥州立大学为种植者和食品加工商提供农业项目。我们有 在方法开发和验证方面有丰富经验。通过新墨西哥合作社 推广服务计划，我们为种植者和食品加工商提供食品安全和 防守。我们使用BAM和新的快速测试方法进行定期的能力测试和验证。 如有要求，我们会参与监视活动。我们是电子实验室的成员 交换网络(ELEXNET)电子通信计划。2014年，我们加入了FDA 全基因组计划，并获得了一台Illumina MiSeq台式测序仪和 来自CFSAN的测序。 NMSU FSL计划继续为FDA测序致病微生物，通过 GenomTrakr网络和NCBI。 作为GenomTrakr实验室，我们打算继续： 1)400个分离物/年序列 2)按要求参加能力测试和其他FERN/FDA活动 3)参加GenomTrakr半年一次的会议