Mentoring and Patient-Oriented Research in Mind-Body Exercise

这项职业中期研究者奖（K24）提案将支持格洛丽亚叶博士进行以患者为导向的研究， 在综合医学领域指导受训人员。在过去的16年里，叶博士开发了一种 以生活方式和冥想练习为重点的综合医学研究的成功计划 心血管和肺部疾病的干预措施。叶博士的研究项目是在贝丝 以色列女执事医疗中心在哈佛医学院，在那里她担任主任身心 美国国立卫生研究院国家补充和综合研究中心主任 健康（NIH NCCIH）资助的T32奖学金（哈佛医学院综合研究奖学金） 医学）。叶博士目前的研究计划包括两个NCCIH R 01赠款，她担任一个 主要研究者，以及她作为主要合作者的其他几项研究。K24提案 概述了职业发展计划，以提高她的研究计划和质量/数量 辅导，包括参加领导和辅导培训，额外的课程（高级） 生物统计学、混合方法和研究内容相关的培训），并定期与已建立的 高级教师顾问。该方案的总体目标突出了三个中心主题， 研究和未来扩展的领域：1）进行严格的研究，评估临床疗效， 心血管和肺部疾病及其他慢性疾病的身心治疗机制; （2）采用创新方法，更好地了解个人的贡献，积极组成部分， 多模式行为，身心方法;和3）调查复杂的患者因素， 影响参与和坚持健康的生活方式，特别是锻炼，以及如何针对身心 治疗可以增强/支持这一点。有了K24提供的保护时间，叶博士计划 她在这些领域的研究，并提供了一个多样化的，创造性的和支持性的研究环境，导师 并培训初级研究人员进行综合医学研究。

This Midcareer Investigator Award (K24) proposal will support Dr. Gloria Yeh in patient-oriented research and mentoring of trainees in the field of integrative medicine. Over the past 16 years, Dr. Yeh has developed a successful program of integrative medicine research with focus on lifestyle and meditative exercise interventions for cardiovascular and pulmonary conditions. Dr. Yeh's research program is based at the Beth Israel Deaconess Medical Center at Harvard Medical School, where she serves as Director of Mind-Body Research, Director of the National Institutes of Health National Center for Complementary and Integrative Health (NIH NCCIH) funded T32 fellowship (Harvard Medical School Research Fellowship in Integrative Medicine). Dr. Yeh's current research program includes two NCCIH R01 grants for which she serve as a principal investigator, and several other studies for which she serves as a key collaborator. This K24 proposal outlines career development initiatives for enhancing her research program and the quality/quantity of mentoring including participation in leadership and mentoring training, additional coursework (in advanced biostatistics, mixed methods, and research content-related trainings), and regular meetings with established senior faculty advisors. The overall Program Aims highlight three central themes which represent current research and areas of future expansion:1) To conduct rigorous research evaluating the clinical efficacy and mechanisms of mind-body therapies in cardiovascular and pulmonary disease and other chronic conditions; 2)To apply innovative methodology to better understand the contributions of individual, active components of multimodal behavioral, mind-body approaches; and 3) To investigate the complex array of patient factors that impact engagement and adherence to healthy lifestyle, particularly exercise, and how targeted mind-body therapies can augment/support this. With the protected time afforded by this K24, Dr. Yeh plans to advance her research in these areas and provide a diverse, creative, and supportive research environment to mentor and train junior investigators in integrative medicine.