CLINICAL TRIAL: MIND-BODY EXERCISE FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE: PI

临床试验：针对慢性阻塞性肺疾病的身心锻炼：PI

• 批准号: 7718946
• 负责人: GLORIA Y YEH
• 金额: $ 0.13万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7718946
• 关键词: Adherence; Breathing; Caring; Chronic Obstructive Airway Disease; Clinical Trials; Computer Retrieval of Information on Scientific Projects Database; Condition; Consensus; Daily; Dyspnea; Exercise; Funding; Grant; Heart Rate; Institution; Measurement; Moods; Morbidity - disease rate; Operative Surgical Procedures; Outcome; Patients; Personal Satisfaction; Physiological; Population; Pulmonary function tests; Randomized; Research; Research Personnel; Resources; Self Efficacy; Self Perception; Source; Symptoms; Tai Ji; United States National Institutes of Health; Week; body-mind; cost; health related quality of life; mortality; pilot trial; programs; prospective; psychosocial; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Chronic obstructive pulmonary disease (COPD)is a major cause of morbidity and mortality. Despite advances in pharmacologic and surgical therapy, many patients suffer from substantial limitations in daily activities. Although exercise is often cited as an important component of treatment, there is no consensus on optimal type and duration of exercise, and adherence to conventional exercise program is problematic. Tai chi, a meditative gentle mind-body exercise with a focus on self-awareness and efficient, regulated breathing, may offer advantages to this population and may be well suited to poorly conditioned patients with COPD. This prospective, randomized pilot trial of 12 patients will investigate whether a tailored 12-week Tai chi program may be safe and beneficial for patients with COPD as compared to a usual care control. This study will also estimate Tai chi exercise intensity, explore psychosocial and physiological responses to mind-body exercise and provide preliminary estimates of cost. Outcome measurements include exercise capacity, health related quality-of-life, mood, pulmonary function tests, symptoms of dyspnea, COPD self-efficacy, heart rate varialibility and autonomic tone.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 慢性阻塞性肺疾病（COPD）是发病率和死亡率的主要原因。尽管药物和手术治疗取得了进步，但许多患者的日常活动受到严重限制。尽管运动经常被认为是治疗的重要组成部分，但对于运动的最佳类型和持续时间尚未达成共识，并且遵守传统的运动计划也存在问题。太极拳是一种冥想性温和的身心锻炼，注重自我意识和有效、调节呼吸，可能为这一人群带来优势，并且可能非常适合身体状况不佳的慢性阻塞性肺病患者。 这项针对 12 名患者的前瞻性、随机试点试验将调查与常规护理对照相比，定制的 12 周太极拳项目是否对 COPD 患者安全且有益。这项研究还将估计太极拳运动强度，探索身心运动的心理社会和生理反应，并提供成本的初步估计。结果测量包括运动能力、健康相关的生活质量、情绪、肺功能测试、呼吸困难症状、慢性阻塞性肺病自我效能、心率变异性和自主神经张力。