The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial blooms
气候和人为驱动因素对有毒蓝藻水华的协同影响
基本信息
- 批准号:9976540
- 负责人:
- 金额:$ 12.88万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-09-30 至 2023-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAgricultureAlgaeAlgal BloomsBiological AvailabilityBiomassBudgetsCharacteristicsChemicalsClimateCommunitiesCuesCyanobacteriumDataData SetDevelopmentEcologyEnvironmental HealthEventExposure toFresh WaterGoalsGrowthHabitatsHealthHumanMetagenomicsMicrobeMicrocystisMolecular BiologyNatural ResourcesNatureNitratesNitrogenNutrientOrganismPathway interactionsPhysiologyPlayPopulationProductionResearch PriorityResearch Project GrantsRiskRoleSeveritiesShapesSourceStructureSurveysSystemSystems BiologyTechniquesTemperatureTestingToxic effectToxinUreaUrsidae FamilyVariantWaterWater SupplyWorkanthropogenesisclimate changecyanobacterial toxindata managementdata resourcedesignenvironmental chemistryexperimental studyharmful algal bloomshepatotoxinhuman diseaseinterdisciplinary approachmembermetabolomicsmetatranscriptomicsmicrobial communitymicrobiomemicrobiotamicrocystinsuccesstooltranscriptomicstrigger pointwaterborne
项目摘要
Project Summary
Cyanobacterial bloom events are shaped by environmental cues that contribute to harmful algal bloom (cHAB)
composition and toxigenicity. Indeed, in Lake Erie, two distinctly different cyanobacterial genera, Microcystis
and Planktothrix, produce microcystin, a potent hepatotoxin. Whereas both cyanobacteria bloom in waters
affected by nutrients delivered by agricultural runoff, Microcystis typically blooms in offshore waters, and
Planktothrix dominates nearshore embayments. Prior work has suggested a role of climate-change induced
temperature increases in promoting growth of Microcystis, and that Planktothrix persists in waters affected by
prolonged nitrogen depletion. Given the different characteristics of these two organisms, limiting exposure to
microcystin may require different management strategies to protect the water supply. Our overarching aim in
this project is to address the extent to which N availability and temperature play in the development,
toxigenicity and persistence of cHAB taxa in Lake Erie and other bloom-affected freshwaters. Informed
by baseline data from metatranscriptomic surveys, we will design microcosm and chemostat experiments aimed
at understanding competition between the two Lake Erie cHAB genera and factors contributing to bloom toxicity.
Specifically, we will test three hypotheses in this project listed below:
1) Nitrogen availability controls cHAB community structure. Microcosms of mixed Microcystis and
Planktothrix bloom communities will be exposed to different regimes of N availability and temperature to
determine the degree to which each contribute to the dominance of one bloom-former over another.
2) Microcystin production is dependent on temperature and N speciation. Chemostat studies of Microcystis
and Planktothrix cultures at control and warmer temperature will reveal how different chemical forms of
N (nitrate vs. urea) promote growth and toxin production.
3) The proliferation of cHAB species is promoted by the activity of the limnetic microbiome.
Metatransciptomic analysis of bloom communities will provide an assessment of the activities of the entire
microbial consortium in cHAB events in order to determine what organisms and pathways assist in cHAB
development, persistence and decline.
A second aim of this project is to generate a comprehensive Lake Erie environmental `omics data set that can
be shared and utilized by the integrated research projects within the Great Lakes Center for Fresh Waters and
Human Health.
项目摘要
蓝藻水华事件是由有害藻华(cHAB)的环境线索形成的
组成和生物活性。事实上,在伊利湖,两个明显不同的蓝藻属,微囊藻
和浮游发藻,产生微囊藻毒素,一种有效的肝毒素。而这两种蓝藻都在沃茨中大量繁殖
受农业径流输送的营养物质影响,微囊藻通常在近海沃茨大量繁殖,
浮游发藻在近岸海湾中占优势。先前的研究表明,气候变化引起的
温度升高促进微囊藻的生长,而浮游发藻在受温度升高影响的沃茨中持续存在。
长期的氮消耗。鉴于这两种生物的不同特性,
微囊藻毒素可能需要不同的管理策略来保护供水。我们的首要目标是
本项目旨在研究氮素有效性和温度在发展中的作用,
伊利湖和其他受水华影响的淡水中cHAB分类群的产毒性和持久性。知情
通过元转录组学调查的基线数据,我们将设计微观世界和恒化器实验,
了解两个伊利湖cHAB属之间的竞争和导致水华毒性的因素。
具体而言,我们将在本项目中测试以下三个假设:
1)氮的有效性控制cHAB群落结构。混合微囊藻的微宇宙和
浮游发藻水华群落将暴露于不同的氮供应和温度制度,
确定每一种对一种开花形成剂相对于另一种开花形成剂的优势的贡献程度。
2)微囊藻毒素的产生依赖于温度和氮的形态。微囊藻的恒化器研究
在控制温度和更高温度下培养的浮游发藻将揭示不同的化学形式
氮(硝酸盐与尿素)促进生长和毒素的产生。
3)湖沼微生物组的活性促进了cHAB物种的增殖。
Bloom社区的元transsciptomic分析将提供对整个社区活动的评估。
微生物联合体的cHAB事件,以确定什么生物和途径有助于cHAB
发展、持续和衰退。
该项目的第二个目标是生成一个全面的伊利湖环境组学数据集,
由五大湖淡水沃茨中心内的综合研究项目共享和利用,
人体健康
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
George S Bullerjahn其他文献
George S Bullerjahn的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('George S Bullerjahn', 18)}}的其他基金
Lake Erie Center for the Great Lakes and Human Health
伊利湖五大湖与人类健康中心
- 批准号:
10427310 - 财政年份:2018
- 资助金额:
$ 12.88万 - 项目类别:
Lake Erie Center for the Great Lakes and Human Health
伊利湖五大湖与人类健康中心
- 批准号:
9789300 - 财政年份:2018
- 资助金额:
$ 12.88万 - 项目类别:
The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial blooms
气候和人为驱动因素对有毒蓝藻水华的协同影响
- 批准号:
10427315 - 财政年份:2018
- 资助金额:
$ 12.88万 - 项目类别:
Lake Erie Center for the Great Lakes and Human Health
伊利湖五大湖与人类健康中心
- 批准号:
9976529 - 财政年份:2018
- 资助金额:
$ 12.88万 - 项目类别:
The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial blooms
气候和人为驱动因素对有毒蓝藻水华的协同影响
- 批准号:
9789304 - 财政年份:
- 资助金额:
$ 12.88万 - 项目类别:
相似海外基金
RII Track-4:NSF: From the Ground Up to the Air Above Coastal Dunes: How Groundwater and Evaporation Affect the Mechanism of Wind Erosion
RII Track-4:NSF:从地面到沿海沙丘上方的空气:地下水和蒸发如何影响风蚀机制
- 批准号:
2327346 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Standard Grant
BRC-BIO: Establishing Astrangia poculata as a study system to understand how multi-partner symbiotic interactions affect pathogen response in cnidarians
BRC-BIO:建立 Astrangia poculata 作为研究系统,以了解多伙伴共生相互作用如何影响刺胞动物的病原体反应
- 批准号:
2312555 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Standard Grant
How Does Particle Material Properties Insoluble and Partially Soluble Affect Sensory Perception Of Fat based Products
不溶性和部分可溶的颗粒材料特性如何影响脂肪基产品的感官知觉
- 批准号:
BB/Z514391/1 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Training Grant
Graduating in Austerity: Do Welfare Cuts Affect the Career Path of University Students?
紧缩毕业:福利削减会影响大学生的职业道路吗?
- 批准号:
ES/Z502595/1 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Fellowship
感性個人差指標 Affect-X の構築とビスポークAIサービスの基盤確立
建立个人敏感度指数 Affect-X 并为定制人工智能服务奠定基础
- 批准号:
23K24936 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Insecure lives and the policy disconnect: How multiple insecurities affect Levelling Up and what joined-up policy can do to help
不安全的生活和政策脱节:多种不安全因素如何影响升级以及联合政策可以提供哪些帮助
- 批准号:
ES/Z000149/1 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Research Grant
How does metal binding affect the function of proteins targeted by a devastating pathogen of cereal crops?
金属结合如何影响谷类作物毁灭性病原体靶向的蛋白质的功能?
- 批准号:
2901648 - 财政年份:2024
- 资助金额:
$ 12.88万 - 项目类别:
Studentship
ERI: Developing a Trust-supporting Design Framework with Affect for Human-AI Collaboration
ERI:开发一个支持信任的设计框架,影响人类与人工智能的协作
- 批准号:
2301846 - 财政年份:2023
- 资助金额:
$ 12.88万 - 项目类别:
Standard Grant
Investigating how double-negative T cells affect anti-leukemic and GvHD-inducing activities of conventional T cells
研究双阴性 T 细胞如何影响传统 T 细胞的抗白血病和 GvHD 诱导活性
- 批准号:
488039 - 财政年份:2023
- 资助金额:
$ 12.88万 - 项目类别:
Operating Grants
How motor impairments due to neurodegenerative diseases affect masticatory movements
神经退行性疾病引起的运动障碍如何影响咀嚼运动
- 批准号:
23K16076 - 财政年份:2023
- 资助金额:
$ 12.88万 - 项目类别:
Grant-in-Aid for Early-Career Scientists