2020/2022 Auditory System GRC/GRS

项目摘要 听觉GRC和GRS一起提供了独特的功能组合，包括：研究的广度，切割- 边缘强调，混合调查人员从各级和不同的子领域和地区，亲密的大小和 延长讨论时间。其中一些特征来自听力研究领域的独特品质， 其他人则来自戈登会议的既定性质和非常成功的形式。 2020年会议的总主题利用了方法和理论的创新，重点是 对预防听觉系统功能丧失和恢复听觉系统功能的综合理解。这些主题 被广泛地解释为涵盖对造成限制和破坏的基本和病理机制的研究。 正常的听觉功能转化为治疗疾病的努力，以及新的治疗和生物学 干预以恢复功能。2022年会议的总主题尚未确定，但将 使用类似的方法，整合听觉系统各个层次的研究。 Sessions将从听觉系统的基本外围机制到中枢通路， 多感官整合和行为输出。该计划将包括正常的病因和病理 听觉功能，疾病和创伤造成的功能中断，以及预防 听力损失和损失后恢复功能。研究人员将强调不同的模型系统， 技术，临床相关性，以及修复受损听觉系统的潜在翻译工具， 包括干细胞治疗、毛细胞再生、基因治疗和下一代耳蜗植入。 我们将设计一些能够吸引不同背景的科学家的会议。我们 奋进强调从斑马鱼到人类的不同模型系统以及分子和生物技术 遗传到系统和行为。在整个会议期间，我们将包括广泛的会谈，重点是 中央和外周听觉神经科学的研究，并将包括更广泛的主题为2020年 和2022年听觉GRC。我们的目标是在整个会议期间鼓励异常高的出席率，并跨- 跨学科施肥。对于听觉GRS，将从提交的摘要中选择演讲， 并由一位受邀的导师-与会者作主旨发言。此外，辅导是一个积极的组成部分， 的GRS。主旨发言人以及GRC组织者将出席非正式和正式会议。 讨论包括研究资助会议，由NIDCD的代表参加，以及职业会议， 展示了在学术界、工业界、出版界和政策等不同领域工作的个人。

PROJECT SUMMARY Together the Auditory GRC & GRS offer a unique combination of features, including: breadth of research, cutting- edge emphasis, mingling of investigators from all ranks and diverse sub-fields and locales, intimate size and extended discussion time. Some of these features arise from unique qualities of the hearing research field and others from the Gordon Conferences’ established nature and highly successful format. The general theme of the 2020 meeting leverages innovation in approaches and theory, focusing on an integrated understanding of preventing loss and recovering function of the auditory system. These topics are broadly construed to span research on basic and pathological mechanisms that pose limitation and destroy normal auditory function to translational efforts to treating disorders and novel therapeutic and biological interventions to recover function. The general theme of the 2022 meeting has not yet been determined, but it will use a similar approach of integrating research across all levels of the auditory system. Sessions will traverse the auditory system from its fundamental peripheral mechanisms to the central pathways, multi-sensory integration, and behavioral output. The program will include the etiology and pathology of normal auditory function, disruption of function through disease and trauma, and innovative approaches to preventing hearing loss and to recovering function after loss. Investigators will highlight different model systems and technologies, clinical relevance, and potential translational tools for repairing damaged auditory systems, including stem cell therapy, hair cell regeneration, gene therapy, and next generation cochlear implants. We will design sessions that have something that will appeal to scientists with diverse backgrounds. We endeavor to highlight different model systems, from zebrafish to humans, and technologies from molecular & genetic to systems and behavior. Throughout the sessions we will include a broad mix of talks that focus on studies of central and peripheral auditory neuroscience and will include the broader thematic topics for the 2020 and 2022 Auditory GRC. Our goal is to encourage unusually high attendance throughout the meeting and cross- fertilization across disciplines. For the Auditory GRS, talks will be selected from submitted abstracts and anchored by a keynote address by an invited mentor-participant. In addition, mentoring is an active component of the GRS. The keynote speaker, as well as the GRC organizers, will be available for informal and formal discussions including a research funding session, featuring a representative from NIDCD, and a career session, featuring individuals working in diverse fields, such as academia, industry, publishing and policy.