ADMINISTRATIVE & BIOSTATICAL CORE

项目摘要 行政核心是我们的计划项目补助金的重要组成部分。大卫哈里森博士，校长 研究者将至少每月一次亲自或通过电话会议与每个项目负责人会面， 个人基础。我们还计划通过电话会议召开所有调查人员的季度小组会议， 研究进展，并计划进一步的研究战略，特别强调在一个领域取得进展的领域， 项目可能导致新的假设的形成，或以其他方式改变研究的进行， 方案领域。我们还计划每年召开PPG研究者和至少两名 外部和内部咨询委员会。 生物统计支持是任何研究计划的关键组成部分。Yu Shyr博士，教授兼主任， 生物统计学系癌症生物统计学部已将本提案的所有组成部分作为一个 顾问和合作者，并将在整个计划期间继续发挥这一作用。支持博士。 因此，Shyr的预算是在这个核心。 本计划的研究者将得到本核心的行政服务的支持，特别是在 准备非竞争性续约、财务管理和组织年度小型网站 咨询委员会的访问。 行政核心将负责协调PPG的办公管理。伯曼女士 范德比尔特临床药理学赠款经理和临床药理学Amy谢尔顿女士 业务经理将监督赠款的所有行政方面，包括进度报告的提交。

PROJECT SUMMARY The administrative core is an essential component of our Program Project Grant. Dr. David Harrison, Principal Investigator, will meet either in person or by conference call with each project leader at least monthly on an individual basis. We also plan quarterly group meetings of all investigators via conference calls to review progress and to plan further research strategies, particularly emphasizing areas in which advances in one project may lead to the formulation of new hypotheses, or otherwise alter the conduct of studies in a different programmatic area. We also plan yearly meetings of the PPG investigators and at least two members of the external and internal advisory committees. Biostatistical support is a critical component of any research program. Dr. Yu Shyr, Professor and Chief, Division of Cancer Biostatistics, Department of Biostatistics, has served all components of this proposal as a consultant and collaborator and will continue this role throughout the duration of the program. Support for Dr. Shyr is therefore budgeted in this core. Investigators in this Program will be supported by the administrative services of this Core, particularly in preparation of non-competing renewals, in financial management, and in organization of the annual mini-site visits of the Advisory Committees. The administrative core will be responsible for coordinating the office management of the PPG. Ms. Berman, the Vanderbilt Grants Manager in Clinical Pharmacology and Ms. Amy Shelton, the Clinical Pharmacology business manager, will oversee all administrative aspects of the grant including progress report submission.