Imaging

先进的成像技术在神经肿瘤学研究中起着至关重要的作用。这个成像核心，即核心4，其目标是 提供专业知识和使用本P01各种项目所需的先进成像设备 求婚。核心的目标是组织项目1-4的需求，并将它们与必要的 专有技术和先进技术。我们将实现三个具体目标：具体目标1： 利用非侵入性成像诊断基底膜，评估纵向进展，并对 心理治疗。具体目标2：直接放射标记我们的新靶向疗法并进行长期评估 生物分布和肿瘤靶向。具体目标3：将局部治疗用药想象为 确保我们先进的运送车辆的正确放置和适当的治疗分配。因此， 酷睿4将为本次PPG应用中的所有项目提供不可或缺的服务。它将符合其中一个 通过提供直接的可视化来开发高效的药物输送手段的最重要的要求 恶性病变、药物对这些病变的可及性及其对治疗反应的变化。核心4 与所有项目的集成代表了我们PPG应用程序的相当大的优势。

Advanced imaging plays a vital role in neuro-oncology research. The goal of this Imaging Core, Core 4, is to provide expertise and access to advanced imaging equipment required by the various projects of this P01 proposal. The objective of the Core is to organize the needs of Projects 1-4 and match them with the requisite know-how and advanced technology. We will accomplish our objectives in three specific aims: Specific Aim 1: To utilize non-invasive imaging to diagnose GBM, evaluate longitudinal progression, and response to therapy. Specific Aim 2: To directly radiolabel our novel targeted therapeutics and evaluate long-term biodistribution and tumor targeting. Specific Aim 3: To image loco-regional therapy administration to ensure proper placement of our advanced delivery vehicles and proper therapeutic distribution. Thus, Core 4 will provide indispensable services to all Projects in this PPG application. It will comply with one of the most important requirements in developing efficient drug delivery means by offering direct visualization of malignant lesions, access of drugs to these lesions and changes in their response to therapy. Core 4 integration with all the projects represents a considerable strength of our PPG application.