Analysis Core

项目摘要/摘要：分析核心 分析核心的首要目标是优化产生的研究的质量和相关性 通过NERC/RCMAR科学家开展的先导研究。这一核心利用了一支久负盛名的团队- 以丰富的现有数据为基础，用复杂的分析方法为年轻学者做好准备 与中心的主题重点相关，以及与全国姊妹大学网络的协同作用， 补充这一使命。它将确保试点研究有效地利用研究资源、使用方法 这最大限度地提高了有效性，并产生了对更大的目标人群具有明确和有意义的推断的结果。至 为了实现这一目标，分析核心成员将密切参与NERC/RCMAR工作的所有方面。我们的 团队综合了流行病学、生物统计学、医学人类学、卫生经济学、 卫生服务和政策以及卫生成果研究，并通过以下方式增强强大的量化能力 在针对少数群体社区的定性方法方面拥有非凡的经验。因此，具体目标是： 1)与研究教育部门合作实施分析方法，以优化效度， 推论，先导研究和拨款申请的概括性；2)确保研究的可靠性和有效性 测量并将测量误差降至最低；3)应用灵活而全面的数据分析策略 基本的横截面和更复杂的数据结构；4)与NERC/RCMAR科学家合作进行试点研究 和他们的导师最大限度地有效利用中心资源；5)适当时，协助先导研究 NERC/RCMAR科学家将定性和定量方法结合起来，以背景和加强 研究的文化相关性和公共卫生影响；6)提供有组织的支持和正式的、说教的 指导；以及7)继续编制和批判性地评价载有关于以下方面信息的数据集目录 由过去和现在的NERC/RCMAR科学家使用的较老的AI/ANS的健康差异。分析核心 将由公共卫生和公共卫生杰出教授斯佩罗·M·曼森博士(Pembina Chippewa)执导 精神病学，美国印第安人和阿拉斯加土著健康中心公共卫生学院主任， 科罗拉多大学安舒茨医学院(UCD/AMC)。曼森博士以他在MIXED中的工作而闻名 方法，具有40年整合定性和定量调查程序的经验，具有 丰富了对人工智能/AN健康的研究。克莱玛·穆勒，博士，护理学院研究助理教授， WSU原生健康合作伙伴(P4NH)联席主任将共同领导这一核心。流行病学家和 她是一名生物统计学家，近15年前作为导师加入NERC/RCMAR，现在担任 这一努力。这一转变反映了她对另外两个由NIH资助的方法和分析核心的领导 由曼森博士和布赫瓦尔德博士领导的中心。他们和他们的团队将最大限度地提高科学严谨性 适应原住民社区在现实世界研究中出现的后勤和方法挑战。

PROJECT SUMMARY/ABSTRACT: ANALYSIS CORE The overarching goal of the Analysis Core is to optimize the quality and relevance of research produced through the Pilot Studies mounted by NERC/RCMAR Scientists. This Core draws on a well-established, team- based approach to preparing young scholars in sophisticated analytic methods, on a rich array of existing data relevant to the Center's thematic focus, and on synergies with a nation-wide network of sister universities that complement this mission. It will ensure that Pilot Studies make efficient use of study resources, use methods that maximize validity, and yield findings with clear and meaningful inference to the larger target populations. To achieve this, Analysis Core members will be intimately involved in all aspects of the NERC/RCMAR effort. Our team integrates diverse methods from epidemiology, biostatistics, medical anthropology, health economics, health services and policy, and health outcomes research, and augments a robust quantitative capacity with exceptional experience in qualitative methods specific to minority communities. Thus, the specific aims are to: 1) collaborate with the Research Education Component to implement analytic methods to optimize validity, inference, and generalizability of Pilot Studies and grant applications; 2) ensure the reliability and validity of study measures and minimize measurement error; 3) apply a flexible and comprehensive data analytic strategy for basic cross-sectional and more complex data structures; 4) partner with Pilot Study NERC/RCMAR Scientists and their mentors to maximize efficient use of Center resources; 5) as appropriate, assist Pilot Study NERC/RCMAR Scientists in integrating qualitative and quantitative methods to contextualize and enhance the cultural relevance and public health impact of their studies; 6) provide structured support and formal, didactic instruction; and 7) continue to develop and critically evaluate a catalogue of data sets containing information on the health disparities of older AI/ANs for use by past and present NERC/RCMAR Scientists. The Analysis Core will be directed by Spero M. Manson, PhD (Pembina Chippewa), Distinguished Professor of Public Health and Psychiatry, and director, Centers from American Indian and Alaska Native Health, School of Public Health, University of Colorado, Anschutz Medical Campus (UCD/AMC). Dr. Manson is well known for his work in mixed methods, with 40 years of experience integrating qualitative and quantitative investigative procedures that has enriched the study of AI/AN health. Clemma Muller, PhD, Research Assistant Professor, School of Nursing, and co-director of Partners for Native Health (P4NH), WSU, will co-lead this Core. An epidemiologist and biostatistician, she joined NERC/RCMAR nearly 15 years ago as a mentor and now moves into a major role in this effort. This transition reflects her leadership of the Methods and Analysis Core of two other NIH-funded centers led by Drs. Manson and Buchwald. They and their team will maximize scientific rigor while accommodating logistical and methodological challenges that arise in real-world research in Native communities.