Stanford TRANSFORM I2T Program

项目摘要/摘要 人类健康的大部分进步是在临床医学和科学创新的交汇处取得的。 在这个关键的十字路口，我们需要一支训练有素的医生和调查员队伍，他们能提出正确的问题 提出问题，做正确的实验，把医学带入未来。尽管迫切需要这支队伍， 从事研究的医生数量正在减少。“改造I2T”的目标(培训 新斯坦福大学教师或住院医生激励感染、免疫学和移植的研究)是 为住院医师、临床研究员和初级临床学院医师提供研究经验 他们职业生涯形成的几年，以便让临床医生-科学家参与基础、翻译或 NIAID任务区的临床研究。通过在住院医师的早期临床培训中暴露他们，我们希望 聘请他们担任传染病、免疫学和移植方面的内科研究员，以便他们 可能会对国家的健康相关研究需求产生重大影响。通过曝光临床研究员 和初级临床教员有合作科研的机会，我们希望激发特定的兴趣，这将 告知和指导这些子专业的职业，并为成功的职业生涯培训医生，如 协作型调查员。我们建议让所有受训人员做好准备，无论他们是否打算进行 他们在长椅上或床边的研究--将他们的科学发现转化为临床实践。至 为此，我们要求每年为5名参与者提供支持，为期3至11个月的研究培训。 住院医师候选人将从特殊内科培训计划中挑选出来，地点为 斯坦福大学-这个项目一直吸引着一些最优秀的毕业生 研究密集型医学院。我们预计传染病/地理科 医学和免疫学/风湿病学将提供大多数同级和初级教员候选人。 来自实体器官移植发挥主要作用的其他科室的研究员和初级教员(例如， 肾脏病、胃肠病和肝病、肺病和重症监护医学)也将被邀请 参与其中。选择进入转型I2T将基于优异的学术成绩，教职员工 面试，以及对研究的浓厚兴趣。将尽一切努力吸引来自 代表不足的少数群体和其他弱势群体(例如，残疾人、“长途旅行”)。 该计划旨在满足临床医生在相关研究方法方面接受培训的公认需求 传染病、免疫学和移植--所有这些都是卫生部公认的优势 斯坦福大学医学院的医学博士。从这里毕业的住院医师学员 该计划预计将过渡到研究密集型奖学金；同事和初级教员参与者将 做好充分准备，通过临床医学和公共卫生的交叉点来加强和改造公共卫生 研究。

Project Summary/Abstract The majority of human health advances are made at intersection of clinical medicine and scientific innovation. At this essential intersection, we need a cadre of trained physician-investigators who can ask the right questions, do the right experiments, and move medicine into the future. Despite the urgent need for this cohort, the number of physicians engaged in research is diminishing. The objectives of “TRANSFORM I2T” (Training in Research for New Stanford Faculty Or Residents Motivating Infection, Immunology, and Transplantation) are to provide resident, clinical fellow, and junior clinical faculty physicians with research experiences in the formative years of their careers, in order to engage clinician-scientists to participate in basic, translational, or clinical research in NIAID mission areas. By exposing residents during their early clinical training, we hope to engage them as physician-investigators in Infectious Diseases, Immunology, and Transplantation, so that they may have a significant impact on the health-related research needs of the nation. By exposing clinical fellows and junior clinical faculty to team-science research opportunities, we hope to spark specific interests that will inform and direct careers in these subspecialties, and to train physicians for successful careers as collaborative investigators. We propose to prepare all trainees—irrespective of whether they intend to conduct their research at the bench or from the bedside—to translate their scientific discoveries into clinical practice. To this end, we request support for 5 participants each year, for a research training period of 3 to 11 months. Resident physician candidates will be selected from the exceptional internal medicine training program at Stanford – a program that has consistently attracted some of the most highly qualified graduates from research-intensive Schools of Medicine. We anticipate that the Divisions of Infectious Diseases/Geographic Medicine and Immunology/ Rheumatology will provide the majority of fellow and junior faculty candidates. Fellows and junior faculty from other divisions in which solid organ transplantation plays a major role (e.g., Nephrology, Gastroenterology and Hepatology, and Pulmonary and Critical Care Medicine) will also be invited to participate. Selection into TRANSFORM I2T will be based on exceptional academic record, faculty interviews, and a strong interest in research. Every effort will be made to attract participants from underrepresented minority and other disadvantaged groups (e.g. disabled persons, long “distance traveled”). The program intends to meet a recognized need for clinicians trained in research methods relevant to Infectious Diseases, Immunology, and Transplantation - all recognized strengths of the Department of Medicine at Stanford University School of Medicine. Graduating resident physician participants from this program are expected to transition to research-intensive fellowships; fellow and junior faculty participants will be well prepared to enhance and “transform” public health through the intersection of clinical medicine and research.