Stanford TRANSFORM I2T Program

斯坦福大学 TRANSFORM I2T 计划

• 批准号: 10663863
• 负责人: GLENN MATTHEW CHERTOW
• 金额: $ 35.1万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10663863
• 关键词: Advisory Committees; Agreement; Area; Award; Basic Science; Biomedical Research; Cancer Education Grant Program; Clinical; Clinical Medicine; Clinical Research; Communicable Diseases; Communities; Cost Sharing; Critical Care; Data; Disabled Persons; Disparity population; Doctor of Medicine; Ensure; Environment; Epidemiology; Exposure to; Faculty; Fellowship; Foundations; Funding; Future; Gastroenterology; Generations; Geography; Goals; Grant; Health; Health Services; Hepatology; Human; Immunology; Infection; Infrastructure; Intellectual Interest; Internal Medicine; Interview; Investments; K-Series Research Career Programs; Leadership; Lung; Medicine; Mentors; Mission; National Institute of Allergy and Infectious Disease; Nephrology; Nursing Faculty; Organ Transplantation; Outcome; Participant; Peer Review; Persons; Physicians; Play; Positioning Attribute; Principal Investigator; Program Development; Public Health; Publications; Qualifying; Records; Research; Research Methodology; Research Personnel; Research Training; Residencies; Resources; Rheumatology; Role; Science; Scientist; Solid; Structure; Training; Training Programs; Translating; Translational Research; Transplantation; Travel; Underrepresented Minority; Universities; Woman; Work; career; clinical care; clinical practice; clinical training; cohort; epidemiology study; experience; experimental study; faculty community; improved; innovation; interest; investigator training; medical schools; meetings; patient oriented; post-doctoral training; pre-doctoral; programs; recruit; success

Project Summary/Abstract The majority of human health advances are made at intersection of clinical medicine and scientific innovation. At this essential intersection, we need a cadre of trained physician-investigators who can ask the right questions, do the right experiments, and move medicine into the future. Despite the urgent need for this cohort, the number of physicians engaged in research is diminishing. The objectives of “TRANSFORM I2T” (Training in Research for New Stanford Faculty Or Residents Motivating Infection, Immunology, and Transplantation) are to provide resident, clinical fellow, and junior clinical faculty physicians with research experiences in the formative years of their careers, in order to engage clinician-scientists to participate in basic, translational, or clinical research in NIAID mission areas. By exposing residents during their early clinical training, we hope to engage them as physician-investigators in Infectious Diseases, Immunology, and Transplantation, so that they may have a significant impact on the health-related research needs of the nation. By exposing clinical fellows and junior clinical faculty to team-science research opportunities, we hope to spark specific interests that will inform and direct careers in these subspecialties, and to train physicians for successful careers as collaborative investigators. We propose to prepare all trainees—irrespective of whether they intend to conduct their research at the bench or from the bedside—to translate their scientific discoveries into clinical practice. To this end, we request support for 5 participants each year, for a research training period of 3 to 11 months. Resident physician candidates will be selected from the exceptional internal medicine training program at Stanford – a program that has consistently attracted some of the most highly qualified graduates from research-intensive Schools of Medicine. We anticipate that the Divisions of Infectious Diseases/Geographic Medicine and Immunology/ Rheumatology will provide the majority of fellow and junior faculty candidates. Fellows and junior faculty from other divisions in which solid organ transplantation plays a major role (e.g., Nephrology, Gastroenterology and Hepatology, and Pulmonary and Critical Care Medicine) will also be invited to participate. Selection into TRANSFORM I2T will be based on exceptional academic record, faculty interviews, and a strong interest in research. Every effort will be made to attract participants from underrepresented minority and other disadvantaged groups (e.g. disabled persons, long “distance traveled”). The program intends to meet a recognized need for clinicians trained in research methods relevant to Infectious Diseases, Immunology, and Transplantation - all recognized strengths of the Department of Medicine at Stanford University School of Medicine. Graduating resident physician participants from this program are expected to transition to research-intensive fellowships; fellow and junior faculty participants will be well prepared to enhance and “transform” public health through the intersection of clinical medicine and research.

项目总结/摘要 大多数人类健康进步都是在临床医学和科学创新的交叉点上取得的。 在这个重要的十字路口，我们需要一支训练有素的医生调查员队伍， 提出问题，做正确的实验，并将医学推向未来。尽管迫切需要这批人， 从事研究的医生人数正在减少。“转变I2 T”的目标（ 研究新的斯坦福大学教师或居民动机感染，免疫学和移植）是 为住院医师、临床研究员和初级临床系医师提供研究经验， 他们的职业生涯的形成年，以从事临床科学家参与基础，转化，或 NIAID使命领域的临床研究。通过在早期临床培训期间暴露居民，我们希望 聘请他们作为传染病，免疫学和移植的医生调查员，以便他们 可能会对国家的健康相关研究需求产生重大影响。通过暴露临床研究员 和初级临床教师团队科学研究的机会，我们希望激发具体的利益，将 告知和指导这些子专业的职业生涯，并培训医生成功的职业生涯， 合作调查员。我们建议为所有受训人员做好准备，无论他们是否打算 他们的研究在板凳上或从床边-把他们的科学发现转化为临床实践。到 为此，我们请求每年支助5名参与者，为期3至11个月的研究培训。 住院医师候选人将从特殊的内科培训计划中选出， 斯坦福大学-一个项目，一直吸引了一些最高素质的毕业生从 研究密集型医学院。我们预计，传染病/地理部门 医学和免疫学/流变学将提供大多数研究员和初级教师候选人。 研究员和初级教师从其他部门，其中实体器官移植发挥了重要作用（例如， 肾脏病学、胃肠病学和肝病学以及肺病和重症监护医学）也将受到邀请 参与其中选择进入转型I2 T将基于卓越的学术成绩，教师 采访，以及对研究的浓厚兴趣。将尽一切努力吸引来自 代表性不足的少数群体和其他弱势群体（如残疾人、长途旅行者）。 该计划旨在满足临床医生在相关研究方法培训的公认需求， 传染病，免疫学和移植-所有公认的优势部门 医学在斯坦福大学医学院。毕业的住院医师参与者从这个 计划预计将过渡到研究密集型奖学金;研究员和初级教师参与者将 做好充分准备，通过临床医学和 research.

项目成果

Genetic association between atopic disease and osteoarthritis.

特应性疾病和骨关节炎之间的遗传关联。

• DOI: 10.1016/j.joca.2023.11.003
• 发表时间: 2024
• 期刊: Osteoarthritis and cartilage
• 影响因子: 7
• 作者: Baker,MatthewC;Robinson,WilliamH;Ostrom,Quinn
• 通讯作者: Ostrom,Quinn

Cohort Study of Maternal Gestational Weight Gain, Gestational Diabetes, and Childhood Asthma.

• DOI: 10.3390/nu14235188
• 发表时间: 2022-12-06
• 期刊: Nutrients
• 影响因子: 5.9

Comparison of Adverse Events Among Home- vs Facility-Administered Biologic Infusions, 2007-2017.

• DOI: 10.1001/jamanetworkopen.2021.10268
• 发表时间: 2021-06-01
• 期刊: JAMA network open
• 影响因子: 13.8
• 作者: Baker MC;Weng Y;Fairchild R;Ahuja N;Rohatgi N
• 通讯作者: Rohatgi N

National Trends and Waitlist Outcomes of Locoregional Therapy Among Liver Transplant Candidates With Hepatocellular Carcinoma in the United States.

• DOI: 10.1016/j.cgh.2021.07.048
• 发表时间: 2022-05
• 期刊: Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Characterization of autonomic symptom burden in long COVID: A global survey of 2,314 adults.

• DOI: 10.3389/fneur.2022.1012668
• 发表时间: 2022
• 期刊: FRONTIERS IN NEUROLOGY
• 影响因子: 3.4
• 作者: Larsen, Nicholas W.;Stiles, Lauren E.;Shaik, Ruba;Schneider, Logan;Muppidi, Srikanth;Tsui, Cheuk To;Geng, Linda N.;Bonilla, Hector;Miglis, Mitchell G.
• 通讯作者: Miglis, Mitchell G.