Mentoring in Patient Oriented Research on Food Insecurity, HIV and Aging

指导以患者为中心的粮食不安全、艾滋病毒和老龄化研究

基本信息

批准号：
10199923
负责人：
SHERI Dawn WEISER
金额：
$ 18.81万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-14 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10199923
关键词：
AIDS/HIV problem Address Adult Affect Age Aging Area Award Behavioral Censuses Chronic Chronic Disease Cognition Disorders Cognitive Color Data Data Collection Development Development Plans Diet Discipline Disease Outcome Educational process of instructing Effectiveness Emergency department visit Environment Epidemiology Ethnic Origin Exercise Food Funding Future Geriatrics Goals Government Grant HIV Hair Health Hospitalization Hydrocortisone Immunologics Impaired cognition Incidence Individual Infrastructure International Internist Intervention Lead Leadership Learning Link Longitudinal cohort Measurement Measures Mediating Mediator of activation protein Mental Depression Mental Health Mentors Methods Modeling Morbidity - disease rate Neighborhoods Neurocognitive Neurology Nongovernmental Organizations Nutritional Nutritional status Nutritive Value Outcome Pathway interactions Persons Play Policies Population Prevention program Psyche structure Psychology Research Research Personnel Research Project Grants Risk Role Sampling Severities Shapes Smoking Stress Structure Systems Integration Time Training Treatment outcome United States National Institutes of Health Woman Women&apos s Interagency HIV Study Work aging population care delivery career career development cognitive function cost dietary early onset effective intervention experience food insecurity food security frailty health disparity improved innovation interest medical appointment men mortality multidisciplinary multilevel analysis next generation novel nutrition older women patient oriented research perceived stress programs public health relevance recruit research study skills social training opportunity treatment program virology

项目摘要

Project Summary Dr. Weiser is an internist trained in HIV epidemiology whose research program focuses on the intersection between food insecurity (FI) and health outcomes in HIV, and on interventions to reduce FI as a mechanism to improve HIV care delivery. She is a sought-after mentor and won the UCSF Academic Senate Distinction in Mentoring Award. Protected time for mentoring and for an innovative new line of research is instrumental for her to achieve her long-term career goals of becoming an international leader in patient-oriented research (POR) related to FI and HIV health, and of developing a multidisciplinary mentoring program and eventual training hub in this area. This K24 application proposes a comprehensive plan for career development, mentoring, and research, which together work towards the goal of reducing HIV health disparities, including an expansion of her research into a new direction by examining how FI affects aging outcomes in HIV. Her proposed career development plan will provide training in frailty, cognitive disorders of aging, multilevel modeling and geospatial methods, as well as in mentoring and leadership skills. She proposes a structured mentoring program including individual development plans and formal and informal teaching to help mentees reach targeted goals. She will recruit mentees from new disciplines such as geriatrics, neurology and psychology, and more mentees from underrepresented backgrounds as is critical for health disparities research. This mentoring program will help her train the next generation of researchers in FI and HIV. To stimulate innovative POR while providing opportunities for increased, more effective mentoring, she proposes to leverage the platform of the Women's Interagency HIV Study (WIHS) and expand her research into three new domains: 1) determining the impact of FI on aging outcomes including frailty and cognitive impairment; 2) understanding the mechanisms though which FI may mediate these outcomes using a novel conceptual model; and 3) investigating upstream determinants of FI using census tract data. This study is innovative in being: 1) one of the first to determine longitudinal impacts of FI on frailty and cognitive impairment and the first among HIV-infected women; 2) one of the first to assess potential mechanisms for how FI may contribute to frailty and cognitive impairment; and 3) one of the first to evaluate neighborhood-level predictors of FI using a rigorous multi-level modeling approach, and in a large sample of HIV-infected and uninfected women. To accomplish her aims and answer high impact questions at minimal cost, she will leverage data already collected in WIHS, and add measurements of FI and dietary quality for three years. She will also lead a qualitative study to understand the neighborhood- and policy-level contexts of FI and how they shape the lived experiences of health. The proposed research will help Dr. Weiser build a strong interdisciplinary network of early career investigators, provide an opportunity to address her training goals, accelerate progress towards her long- term career goals, and provide preliminary data and training opportunities for her mentees.

项目摘要 Weiser博士是一名受艾滋病毒流行病学培训的内科医生，其研究计划着重于十字路口在艾滋病毒中的粮食不安全（FI）和健康状况之间改善艾滋病毒护理。她是一位受欢迎的导师，并赢得了UCSF学术参议院的区别指导奖。受保护的指导时间和创新的新研究系列对她要实现成为以患者为导向研究的国际领导者的长期职业目标（POR）与FI和HIV健康有关，以及制定多学科指导计划和最终该领域的培训中心。该K24申请提出了一个全面的职业发展计划，指导和研究共同致力于降低艾滋病毒健康差异的目标通过研究FI如何影响艾滋病毒的衰老结果，将她的研究扩展到一个新的方向。她拟议的职业发展计划将为衰老，多层次的认知障碍提供培训建模和地理空间方法以及指导和领导能力。她提出了一个结构化的指导计划，包括个人发展计划以及正式和非正式教学，以帮助受训者达到目标目标。她将从老年医学，神经病学和心理学，以及更多来自代表性不足的背景的受训者，这对于健康差异至关重要研究。该指导计划将帮助她培训FI和HIV中的下一代研究人员。为了刺激创新的POR，同时为增加，更有效的指导提供机会，她建议利用妇女跨机构艾滋病毒研究（WIHS）的平台并扩大她的研究分为三个新领域：1）确定FI对包括脆弱和认知在内的衰老结果的影响损害； 2）了解FI可以使用小说来介导这些结果的机制概念模型； 3）使用人口普查数据研究FI的上游决定因素。这项研究是存在创新性：1）最早确定FI对弱和认知障碍的纵向影响的人之一这是艾滋病毒感染的妇女中的第一个； 2）最早评估FI如何可能的潜在机制的之一有助于脆弱和认知障碍； 3）最早评估邻里级预测变量的人之一使用严格的多层次建模方法，在大量的HIV感染和未感染的样本中女性。为了实现她的目标并以最低的成本回答高影响问题，她将利用数据已经在WIHS中收集，并添加了三年的FI和饮食质量的测量。她也会领导一项定性研究，以了解FI的邻里和政策级别环境及其如何塑造健康的经历。拟议的研究将帮助Weiser博士建立一个强大的跨学科网络早期职业调查人员的机会，提供了解决她的培训目标，加速进步的机会她的长期职业目标，并为受训者提供初步的数据和培训机会。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Food insufficiency and mental health service utilisation in the USA during the COVID-19 pandemic.

DOI：
10.1017/s1368980021003001
发表时间：
2022-01
期刊：
Public health nutrition
影响因子：
3.2
作者：
Nagata JM;Ganson KT;Cattle CJ;Whittle HJ;Tsai AC;Weiser SD
通讯作者：
Weiser SD

Food Insufficiency and Mental Health in the U.S. During the COVID-19 Pandemic.

DOI：
10.1016/j.amepre.2020.12.004
发表时间：
2021-04
期刊：
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
影响因子：
5.5
作者：
Nagata, Jason M.;Ganson, Kyle T.;Whittle, Henry J.;Chu, Jonathan;Harris, Orlando O.;Tsai, Alexander C.;Weiser, Sheri D.
通讯作者：
Weiser, Sheri D.

A systematic review and meta-analysis assessing the impact of droughts, flooding, and climate variability on malnutrition.