UNC Oncology Clinical/Translational Research Training Program (OCT-RTP)

北卡罗来纳大学肿瘤学临床/转化研究培训计划 (OCT-RTP)

• 批准号: 10199943
• 负责人: WILLIAM Y. KIM
• 金额: $ 71.89万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-17 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10199943
• 关键词: Adult; Advisory Committees; Basic Science; Cancer Hospital; Clinical; Clinical Oncology; Clinical Trials Design; Clinical and Translational Science Awards; Data Analytics; Enrollment; Foundations; Funding; Goals; Grant; Growth; Leadership; Malignant Neoplasms; Medical Oncology; Medicine; Mentors; Mentorship; Monitor; North Carolina; Oncology; Patient Outcomes Assessments; Pediatric Hematology; Program Reviews; Progress Reports; Radiation Oncology; Records; Research; Research Personnel; Resources; Role; SECTM1 gene; Training; Training Programs; Training and Education; Translational Research; UNC Lineberger Comprehensive Cancer Center; Universities; anticancer research; career development; distinguished professor; experience; mid-career faculty; novel; patient oriented; programs; senior faculty

Abstract In this competing renewal, the University of North Carolina at Chapel Hill (UNC) Divisions of Adult and Pediatric Hematology/Oncology, the Department of Radiation Oncology and the UNC Lineberger Comprehensive Cancer Center (UNC LCCC) seek renewed funding for the UNC Calabresi K12, called the Oncology Clinical/Translational Research Training Program (OCT- RTP). All of the components will contribute mentors and resources to the training program, and all components except the LCCC will contribute scholars. The OCT-RTP will admit two scholars per year. The PI, Dr. Norman Sharpless, is the Wellcome Distinguished Professor in Cancer Research and Director of the LCCC. Dr. Sharpless has extensive experience in oncologic translational research. Dr. Hanna Sanoff, Associate Professor of Medicine and Section Chief of GI Medical Oncology, is an experienced mentor who assumed the role of Program Director (PD) in 2016. The program's objectives are to establish a rigorously trained cadre of researchers who will become successful, independent cancer investigators. Training resources available for the OCT-RTP include: the LCCC, the North Carolina Cancer Hospital and the UNC Clinical and Translational Science Award (CTSA) which supports an Education, Training, and Career Development Core. The goals of the OCT-RTP are to increase the quality and quantity of patient- oriented cancer research. The foundation of the proposed training program will be the participation of highly qualified basic science and clinical mentors assigned to each scholar with mentoring activities coordinated by the K12 leadership. An internal advisory committee (IAC) that includes senior faculty from the program components will select and monitor scholar progress, while an external advisory committee reviews the program annually. Since its inception, the OCT- RTP has enrolled sixteen Scholars, including 10 funded in the last grant cycle whose records are detailed in the progress report. Major changes since our last renewal include a new PD (Dr. Sanoff), changes in the composition of the IAC, greater integration with other UNC training programs, and changes in the mentorship roster. In particular, the mentor roster has been pruned from 40 to 34 mentors to enhance research focus, with the addition of new mentors adding a greater diversity of now-relevant expertise, including notable additions in patient-reported outcomes, data analytics and novel clinical trial design. Facilities and resources for the program have evolved to provide even stronger support, including the leveraging of considerable state support from the University Cancer Research Fund (UCRF). We believe these changes and growth have strengthened a successful and important training program.

摘要 在这次竞争性的更新中，北卡罗来纳州查佩尔山大学（北卡罗来纳州）成人教育部 和儿科血液学/肿瘤学，放射肿瘤学和放射治疗科 Lineberger综合癌症中心（Lineberger Comprehensive Cancer Center，简称LCCC）寻求新的资金支持， Calabresi K12，称为肿瘤学临床/转化研究培训计划（OCT- RTP）。所有的组成部分都将为培训计划提供导师和资源， 除LCCC外，所有组件都将提供学者。OCT-RTP将招收两名学者 每一年。PI，Norman Sharpless博士，是Wellcome癌症杰出教授 LCCC的研究和主任。Sharpless医生在肿瘤学方面有丰富的经验， 翻译研究Hanna Sanoff博士，医学副教授兼 GI医学肿瘤学，是一位经验丰富的导师，担任项目总监（PD） 2016年该计划的目标是建立一支训练有素的研究人员队伍， 将成为成功的独立癌症研究者可供联合国系统各机构 OCT-RTP包括：LCCC，北卡罗来纳州癌症医院和临床和 翻译科学奖（CTSA），支持教育，培训和职业 发展核心。OCT-RTP的目标是提高患者的质量和数量- 以癌症研究为导向。拟议培训计划的基础将是 参与高素质的基础科学和临床导师分配给每个学者， 由K12领导层协调的辅导活动。内部咨询委员会（IAC）， 包括来自该计划组成部分的高级教师将选择和监测学者的进展， 而一个外部咨询委员会每年审查该方案。自成立以来，华侨城- RTP已经招收了16名学者，其中包括10名在上一个赠款周期资助的学者，他们的记录是 详细情况见进度报告。自上次更新以来的主要变化包括新的PD（博士）。 Sanoff），IAC组成的变化，与其他培训机构的更大整合 计划，以及导师名册的变化。特别是，导师名册已被精简， 将导师人数由40人增至34人，以加强研究重点， 现在相关的专业知识更加多样化，包括患者报告的显著增加 结果、数据分析和新型临床试验设计。该计划的设施和资源 已经发展到提供更强大的支持，包括利用相当大的国家 大学癌症研究基金（UCRF）的支持。我们相信这些变化， 增长加强了一个成功和重要的培训计划。