Pilot and Feasibility Program

试点和可行性计划

• 批准号: 10361548
• 负责人: AMITABH CHAK
• 金额: $ 17.59万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-02-15 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10361548
• 关键词: Advisory Committees; Applications Grants; Area; Award; Categories; Clinic; Collaborations; Development; Digestive System Disorders; Fostering; Foundations; Funding; Goals; Grant; Inflammation; Investigation; Investments; K-Series Research Career Programs; Liver diseases; Metabolism; Midwestern United States; Mission; National Institute of Diabetes and Digestive and Kidney Diseases; Outcome; Peer Review; Peer Review Grants; Privatization; Process; Progress Reports; Qualifying; Research; Research Institute; Research Personnel; Resources; Review Committee; Science; Series; Study Section; Talents; Translating; Trust; United States National Institutes of Health; Universities; Update; Work; base; career development; cost; feasibility research; innovation; interest; large bowel Crohn' s disease; member; minority investigator; programs; research study; skills; success; symposium; tumorigenesis

PILOT AND FEASIBILITY PROGRAM PROJECT SUMMARY The Cleveland DDRCC Pilot and Feasibility (P and F) Program is one of the fundamental pillars for the intellectual vitality and success of our Center. The Program directly supports the Center’s stated mission to foster innovation in the area of digestive disease-related research through the support of collaborative research, collaboration, and career development. The overall goal of the P and F program is to grow the number of investigators successfully performing research in the thematic areas of Digestive Inflammation/Tumorigenesis and Liver Disease/Metabolism at Case Western Reserve University (CWRU) Center and the Cleveland Clinic Foundation’s Lerner Research Institute (CCF LRI) by providing resources to develop new pilot and/or feasibility research studies that will lead to competitive peer-reviewed grant applications. The program, directed by Dr. Amitabh Chak, has a focus using P and F awards to support the development of independent research programs for junior investigators with an interest in digestive diseases research. The program also seeks to attract talented, established investigators in other fields to apply their research skills and expertise to digestive disease-related investigations. A call for applications is held each spring, and the program generally receives 20-30 proposals per year. The P and F Scientific Review Committee oversees peer-review of all qualifying applications, including both an internal review process and external review by members of the Cleveland DDRCC External Advisory Committee. The Center funds up to four $25,000 awards per year with NIDDK funding, as well as up to an additional two awards per year supported by institutional commitments. Awards are for one year, but recipients can apply for a second year of funding when needed. The P and F Program annually tracks the outcomes of all current and prior P and F Award recipients, and provides regular Progress Report updates to the NIDDK. We are particularly proud of the high level of success seen with our P and F Program during the previous funding cycle, with seven of our 15 P and F Awardees from 2015-2018 going on obtain peer-reviewed NIH or foundation grants based on work generated through their P and F project (including four K awards, one R01, one R21 for minority investigators, one P20 sub-project PI, two Crohn’s and Colitis Foundation Senior Research Awards, and one Helmsley Trust Award). P and F awardees have also been active in contributing to the enrichment programs of the Cleveland DDRCC, including founding the Young Investigators Network and its highly popular “Mock Study Section”, presenting their P and F projects at the annual Midwest DDRCC Alliance Research Symposium (hosted by the Cleveland DDRCC Mar 5-6, 2018), and organizing and participating in the Young Investigators Symposium included within the biannual two-day Cleveland IDEAS Symposium.

试点和可行性研究项目摘要 克利夫兰DDRCC试点和可行性（P和F）计划是该计划的基本支柱之一。 我们中心的智力活力和成功。该方案直接支持中心的既定使命， 通过支持合作，促进消化系统疾病相关研究领域的创新 研究、协作和职业发展。P和F计划的总体目标是增加 在消化系统专题领域成功开展研究的研究者人数 炎症/肿瘤发生和肝脏疾病/代谢在凯斯西储大学（CWRU） 中心和克利夫兰临床基金会的勒纳研究所（CCF LRI）通过提供资源， 开展新的试点和/或可行性研究，以获得竞争性同行评审赠款 应用.该计划由Amitabh Chak博士指导，重点是使用P和F奖项来支持 为对消化系统疾病感兴趣的初级研究人员制定独立的研究计划 research.该计划还旨在吸引其他领域有才华的知名调查人员， 消化系统疾病相关调查的研究技能和专业知识。每星期举行一次申请电话会议， 春季，该计划通常每年收到20-30份提案。P & F科学评论 委员会监督所有合格申请的同行评审，包括内部评审过程和 克利夫兰复员方案协调委员会外部咨询委员会成员的外部审查。该中心的资金高达 每年四个25，000美元的奖项，由NIDDK资助，以及每年最多两个奖项 得到机构承诺的支持。奖学金为期一年，但获奖者可以申请第二年的奖学金。 在需要时提供资金。P和F计划每年跟踪所有当前和以前的P和F的结果 获奖者，并定期向NIDDK提供进度报告更新。我们特别自豪的是， 在上一个资助周期中，我们的P和F计划取得了很大的成功，我们的七个项目 2015年至2018年的15名P和F获奖者将根据工作获得同行评审的NIH或基金会赠款 通过他们的P和F项目产生的（包括四个K奖，一个R 01，一个R21少数民族调查员，一个R21少数民族调查员，一个R21少数民族调查员， P20子项目PI，两项克罗恩病和结肠炎基金会高级研究奖，一项赫尔姆斯利信托奖）。 P和F获奖者还积极为克利夫兰DDRCC的浓缩计划做出贡献， 包括建立青年调查员网络及其非常受欢迎的“模拟研究部分”，介绍他们的 年度中西部DDRCC联盟研究研讨会上的P和F项目（由克利夫兰DDRCC主办 2018年3月5日至6日），并组织和参加青年研究者研讨会，包括在 为期两天的克利夫兰IDEAS研讨会。