EXTENDING INDEPENDENCE AND QUALITY OF LIFE FOR PEOPLE WITH ALZHEIMER'S DISEASE OR DEMENTIA THROUGH TELEHEALTH PROGRAM DELIVERY

通过远程医疗计划的实施，提高阿尔茨海默病或痴呆症患者的独立性和生活质量

• 批准号: 10204865
• 负责人: Deborah E. Barnes
• 金额: $ 100.34万
• 依托单位: TOGETHER SENIOR HEALTH, INC.
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10204865
• 关键词: Alzheimer' s Disease; Alzheimer' s disease caregiver; American; Behavior Therapy; Behavioral; California; Caregivers; Caring; Child; Client; Clinical Trials; Cognitive; Communities; Control Groups; Couples; Dementia; Development; Devices; Disease; Dose; Education; Elements; Emotional; Environment; Evidence based program; Feedback; Friends; Geriatrics; Goals; Grant; Growth; Health; Home; Human; Integrative Medicine; Intervention Studies; Logistics; Measures; Memory Loss; Methods; Mission; Modeling; Parents; Participant; Personal Satisfaction; Persons; Pharmaceutical Preparations; Phase; Preparation; Prevalence; Psychology; Public Health; Qualitative Methods; Quality of life; Randomized Controlled Trials; Reporting; Research Personnel; Research Proposals; San Francisco; Small Business Innovation Research Grant; Social Problems; Social isolation; Symptoms; Teacher Professional Development; Technology; Testing; Thinking; Training Programs; Training Support; Transportation; Triad Acrylic Resin; Underserved Population; Universities; Vulnerable Populations; Waiting Lists; base; cohort; commercialization; design; digital; distraction; evidence base; experience; improved; innovation; innovative technologies; instructor; live stream; mild cognitive impairment; novel strategies; online delivery; programs; prototype; remote delivery; response; side effect; social; telehealth; tool; user-friendly; virtual; web portal; web site

Mission Statement: Together Senior Health, Inc. (TOGETHER), is committed to helping people living with Alzheimer’s Disease and Related Disorders (ADRD) and their caregivers maximize quality of life by delivering livestreaming, evidence-based, virtual group programs to them in their homes. Significance: There are currently 5.8 million people in the U.S. living with ADRD and more than 16 million unpaid caregivers. Current ADRD medications help with some symptoms but do not change the disease course and are often stopped due to side effects. In addition, most evidence-based behavioral interventions—such as our in-person Moving Together program—are not widely available to people in their local communities. Innovation: TOGETHER is bridging this gap by using human centered design principles—in which the user is involved with all phases of design and testing—to develop and test an innovative, user-friendly platform for delivering livestreaming virtual group programs to people with ADRD and caregivers in their homes. Investigators: TOGETHER’s CEO and PI of this application has expertise in human centered design and successfully led our Phase I Small Business Innovation Research (SBIR) grant. Coinvestigators and consultants bring expertise in clinical trials, integrative health, behavioral psychology, geriatrics, qualitative methods, technology and education. Approach: Phase I Progress. Our Phase I SBIR enabled us to develop and demonstrate proof-of-concept for our unique approach to livestreaming virtual group program delivery. We have completed or exceeded all of our milestones, which included: 1) creating the platform in partnership with graduates of our in-person program; 2) pilot-testing the platform in a naïve group of users and 3) refining the platform in preparation for Phase II. The response has been exceptional, with participants highlighting many physical, social, emotional, and logistical benefits. Phase II Aims: The primary goals of this SBIR Phase II grant are to: 1) determine whether livestreaming virtual group delivery of the Moving Together program improves quality of life in people with mild ADRD and caregivers, including exploration of potential mechanisms of action; 2) refine the platform for people with mild cognitive impairment to expand our target audience; and 3) develop an instructor training program to meet the needs of a larger client base. Environment: TOGETHER’S corporate office is in San Francisco, which offers a rich environment for developing and testing innovative technology-based solutions to challenging social problems and is enhanced by involvement of investigators at the University of California, San Francisco (UCSF) and San Francisco VA. Commercialization Plan: After completion of Phase II, we will be prepared to commercialize TOGETHER’s telehealth platform, initially using a client pay model, with clear plans for growth and expansion. Summary: TOGETHER’s innovative approach to livestreaming virtual group delivery of evidence-based programs for people with ADRD and caregivers in their homes offers tremendous potential to increase access and improve quality of life in this vulnerable and under-served population.

任务陈述：共同的高级健康公司（一起）（一起）致力于帮助居住的人 阿尔茨海默氏病和相关疾病（ADRD）及其护理人员通过交付来最大化生活质量 在家中为他们提供直播，基于证据的虚拟小组计划。意义：有 目前，美国有580万人居住在ADRD和超过1600万的无薪护理人员。当前的 ADRD药物有助于解决某些症状，但不会改变疾病病程，并且经常停止 由于副作用。此外，大多数基于证据的行为干预措施 - 例如我们的面对面搬家 共同计划 - 当地社区中的人们不广泛使用。创新：在一起 通过使用以人为中心的设计原理来弥合这一差距 设计和测试 - 开发和测试一个创新的，用户友好的平台，用于提供生计虚拟 为ADRD和护理人员在家中的人提供小组计划。调查人员：首席执行官和 该应用程序的PI具有人为以人为本设计的专业知识，并成功领导了我们的I阶段小型企业 创新研究（SBIR）赠款。共同评估者和顾问带来了临床试验中的专业知识，综合 健康，行为心理学，老年医学，定性方法，技术和教育。方法：第一阶段 进步。我们的阶段I SBIR使我们能够开发并展示我们独特方法的概念证明 直播虚拟小组程序交付。我们已经完成或超过了所有里程碑， 包括：1）与我们面对面计划的毕业生合作创建平台； 2）试点测试 在幼稚的用户组中的平台和3）完善平台以准备第二阶段。响应有 非常出色，参与者强调了许多身体，社会，情感和后勤上的好处。阶段 II目标：SBIR II阶段授予的主要目标是：1）确定生命的虚拟群体是否存在 交付搬家计划可以改善轻度ADRD和护理人员的生活质量， 包括探索潜在的作用机制； 2）为温和认知的人完善平台 损害扩大我们的目标受众； 3）制定一项讲师培训计划，以满足 更大的客户群。环境：共同的公司办公室在旧金山，提供富裕 开发和测试基于创新技术的解决方案以挑战社会问题的环境 并通过加利福尼亚大学，旧金山（UCSF）和SAN的调查人员参与来增强 弗朗西斯科弗吉尼亚州。商业化计划：第二阶段完成后，我们将准备商业化 共同使用客户薪酬模型的远程医疗平台，并有明确的增长和扩展计划。 摘要：共同的创新方法来实现虚拟群体提供基于证据的群体交付 为ADRD和护理人员的人提供的计划，他们的家中有巨大的潜力来增加访问权限 并改善这个脆弱和服务不足的人口的生活质量。

项目成果

Adaptation of an In-Person Mind-Body Movement Program for People with Cognitive Impairment or Dementia and Care Partners for Online Delivery: Feasibility, Satisfaction and Participant-Reported Outcomes.

• DOI: 10.1177/27536130231202989
• 发表时间: 2023-01
• 期刊: Global advances in integrative medicine and health
• 作者: Nicosia, Francesca M.;Lee, Jennifer A.;Chesney, Margaret A.;Benjamin, Cynthia;Lee, Amanda N.;Mehling, Wolf;Sudore, Rebecca L.;Barnes, Deborah E.
• 通讯作者: Barnes, Deborah E.